Monument MJ, Hart DA, Befus AD, Salo PT, Zhang M, Hildebrand KA: The mast cell stabilizer, ketotifen significantly reduces joint capsule α-smooth muscle actin and TGF-β1 expression and collagen hyperplasia in a rabbit model of posttraumatic joint contractures. Journal of Orthopaedic Research, submitted. Miller D, Salo P, Hart D, Leonard C, Bray RC: Denervation exacerbates vascular dysfunction in the ACL- deficient model of osteoarthritis. Journal of Orthopaedic Research, Submitted. Monument MJ, Hart DA, Zhang M, Salo PT, Befus AD, Hildebrand KA: The mast cell stabilizer, ketotifen fumarate lessens contracture severity and myofibroblast hyperplasia in a rabbit model of posttraumatic joint contractures, Journal of Bone and Joint Surgery, accepted. AlEissa S, Reed J, Kortbeek JB, Salo P: Airway compromise secondary to upper cervical spine injury. The Journal of Trauma, Injury, Infection and Critical Care, in press. Bring DK-I, Reno C, Renstrom P, Salo P, Hart D, Ackermann P: Prolonged immobilization compromises up- regulation of repair genes after tendon rupture in a rat model. Scandinavian Journal of Medicine & Science in Sports, in press. Ackermann PW, Salo PT, Hart DA: Neuronal pathways in tendon healing. Frontiers in Bioscience. Vol 14: 5165-5187, 2009. Liang LS, Salo PT, Hart DA, Burt HM: Intra-articular treatment of inflammatory arthritis with microsphere formulations of methotrexate: pharmacokinetics and efficacy determination in antigen induced arthritic rabbits. Inflammation Research, Vol 58(8):445-456, 2009. Bring DK-I, Reno C, Renstrom P, Salo P, Hart DA, Ackermann PW: Joint immobilization reduces the expression of sensory neuropeptide receptors and impairs healing after tendon rupture in a rat model. Journal of Orthopaedic Research, Vol 27(2): 274-280, 2009. Hildebrand KA, Zhang M, Salo PT, Hart DA: Joint capsule mast cells and neuropeptides are increased within four weeks of injury and remain elevated in chronic stages of post traumatic contractures. Journal of Orthopaedic Research, 26(10):1313-19, 2008. Salo PT, Beye JA, Seerattan RA, Leonard CA, Ivie TJ, Bray RC: Plasticity of peptidergic innervation in healing rabbit medial collateral ligament. Canadian Journal of Surgery, Vol 51(3), pgs 167-172, 2008. Beye JA, Hart DA, Bray RC, Seerattan RA, Leonard CA, Reno CR, Salo PT. Injury induced changes in mRNA levels differ widely between ACL and MCL. American Journal of Sport Medicine, Jul;36(7):1337-46 2008. Mammoto T, Seerattan RA, Paulson KD, Leonard CA, Bray RC, Salo PT: Nerve growth factor improves ligament healing. Journal of Orthopaedic Research, Jul;26(7):957-64, 2008. Salo PT, Bray RC, Seerattan RA, Reno C, McDougall JJ, Hart DA: Neuropeptides regulate expression of matrix molecule, growth factor and inflammatory mediator mRNA in explants of normal and healing medial collateral ligament. Regulatory Peptides, Volume 142:1-2, pgs 1-6, 2007.
Miller D, Forrester K, Leonard C, Hart DA, Salo P, Bray RC: Endothelial dysfunction and decreased vascular responsiveness in the anterior cruciate ligament deficient model of osteoarthritis. Journal of Applied Physiology, 102:1161-1169, 2007. Beye J, Hart DA, Bray RC, Seerattan RA, McDougall JJ, Leonard CA, Reno CR, Salo PT: Denervation alters mRNA levels of repair-associated genes in a rabbit medial collateral ligament injury model. Journal of Orthopaedic Research, 24 (9):1842-1853, 2006. Miller D, Forrester K, Leonard C, Salo P, Bray RC. ACL deficiency impairs the vasoconstrictive efficacy of neuropeptide Y and phenylephrine in articular tissues: A laser speckle perfusion imaging study. Journal of Applied Physiology, 98(1): 329-33, 2005. Ford-Hutchinson AF, Ali Z, Seerattan RA, Cooper DML, Hallgrimsson B, Salo PT, Jirik FR: Degenerative knee joint disease in mice lacking phosphoadenosine-phosphosulfate synthase 2 (Papss2) activity: a putative model of human PAPSS2 deficiency-associated arthrosis. Osteoarthritis and Cartilage, May, 13(5): 418-25, 2005. Bray RC, Salo PT, Lo IKY, Ackermann P, Rattner JB and Hart DA: Normal ligament structure, physiology and function. Sports Medicine and Arthroscopy Review, 13(3): 127-135, 2005. Bray RC, Leonard C, Forrester K, Salo P: Animal models of ligament repair. In: Encyclopedia of Biomaterials and Biomedical Engineering 1 (1), Dekker, 2005.
Chevalier JF, Casha S, Bouchard J, Cho RK, Salo P, DuPlessis SJ, Hurlbert RJ: Vertebral artery ectasia and posterior C1/2 transarticular screw fixation: Real or perceived limitations? Canadian Journal of Neurological Sciences 47:13, 2004. Assiri I, du Plessis S, Hurlbert J, Hu R, Salo P, Whittaker T: A prospective randomized clinical study comparing instrumented lumbar fusion rates of recombinant human bone morphogenic protein-2 (rhBMP-2) with autogenous iliac crest bone graft in patients with symptomatic degenerative disc disease. Canadian Journal of Surgery, Vol. 47:7, 2004. Bray RC, Leonard CA, Salo PT: Correlation of healing capacity with vascular response in the anterior cruciate and medial collateral ligaments of the rabbit. JOR, 21(6): 1118-23, 2003. Bray RC, Leonard CA, Salo PT: Vascular adaptation of intact joint stabilizing structures in the posterior cruciate ligament deficient rabbit knee. JOR, 21:787-791, 2003. Salo PT, Seeratten RA, Erwin WM, Bray RC: Aging, joint innervation and osteoarthritis: Evidence for a neuropathic contribution to the development of spontaneous knee osteoarthritis in a mouse model. Acta Orthopaedica Scandinavica, 73(1): 77-84, 2002. Ivie TJ, Bray RC, Salo PT: Denervation impairs healing of the rabbit medial collateral ligament. Journal of Orthopaedic Research, 20: 990-995, 2002. Bray RC, Leonard CA, Salo PT: Vascular physiology and long-term healing of partial ligament tears. Journal of Orthopaedic Research, 20: 984-989, 2002. Salo PT, Hogervorst T, Seerattan RA, Rucker D, Bray RC: Selective joint denervation promotes knee osteoarthritis in the aging rat. Journal of Orthopaedic Research, 20(6): 1256-1264, 2002. Bray RC, Smith JA, Eng MK, Leonard CA, Sutherland CA, Salo P: Vascular response of the meniscus to injury: effects of immobilization. Journal of Orthopaedic Research, 19: 384-390, 2001.
Lieberman IH, Salo PT, Orr RD, Kraetschmer B: Prone position endoscopic transthoracic release with simultaneous posterior instrumentation for spinal deformity: A description of the technique. Spine 2000: 25:2251-2257. Lieberman IH, Willsher PC, Litwin DEM, Salo PT, Kraetschmer BG, Herkowitz HN. Transperitoneal laparoscopic exposure for lumbar interbody fusion. Spine 2000: 25:509-515. Catre MG, Salo PT: Quantitative assessment of the sympathetic innervation of the rat knee. Journal of Anatomy 1999: 194: pp 233-239. Salo, PT. The role of joint innervation in the pathogenesis of arthritis. Canadian Journal of Surgery 1999:42: pp 91 - 100. Orr RD, Salo PT: Atlanto-axial instability complicating radiation therapy for recurrent nasopharyneal carcinoma: A case report. Spine 1998: 23: pp 1280-1282. Salo PT, Theriault E: Number, distribution and neuropeptide content of rat knee joint afferents. Journal of Anatomy 1997: 190: pp 515-522. Salo PT, Theriault E, Wiley RG: Selective ablation of rat knee joint innervation with injected immunotoxin:
A potential new model for the study of neuropathic arthritis. Journal of Orthopaedic Research 1997:15:
pp 622-628. Tatton WG, Ansari K, Ju W, Salo PT, Yu PH: Selegiline induces 'trophic-like' rescue of dying neurons without MA0-B inhibition. Advances In Experimental Biology 1995: 363: pp Is- 16. Khazim R, Salo PT: Talar neck fracture with talar head dislocation and intact ankle and subtalar joints: A case report. Foot and Ankle 1995: 16, No. 1: pp 44-48. Salo PT, Tatton WG: Age-related loss of knee joint afferents in mice. Journal of Neuroscience Research1993:35: pp 664-677. Salo PT, Tatton WG: Deprenyl reduces the death of motor neurons caused by axotomy. Journal of Neuroscience Research 1992: 3 1: pp 394-400. Tatton WG, Greenwood CE, Seniuk NA, Salo PT: Interactions between MPTP-induced and age-related neuronal death in a murine model of Parkinson's disease. Canadian Journal of Neurological Science 1992: 19(1): pp 124-133. Skubic JW, Kostuik JP, Suh PB, Salo PT: The use of Cotrel-Dubousset instrumentation in the treatment of adult idiopathic scoliosis. Iowa Orthopaedics Journal 1991: 11: pp 137-148. Tatton WG, Greenwood CE, Salo PT, Seniuk NA: Transmitter synthesis increases in substantia nigra neurons of the aged mouse. Neuroscience Letters 1991: 13 1: pp 179-182. Salo PT, Frank CB, Marchuk L: Synovial fluid does not inhibit collagen synthesis: Bovine cruciate ligament studied in vitro. Acta Orthopaedica Scandinavica 1990: 61(6): pp 567-569.
Was ist Viagra und wann wird es angewendet?Viagra ist der erste Vertreter einer neuen Medikamentengruppe mit der Bezeichnung Phosphodiesterase-Typ 5-Inhibitoren. Es wirkt, indem es bei sexuel er Erregung die Entspannung der Blutgefässe in Ihrem Penis unterstuetzt. Dadurch kann Blut leichter in den Penis fliessen und Sie erreichen auf natuerliche Weise eine Erektion. Sie sol en Viagra nicht einn
Cátedra de Farmacología Aplicada CATEDRA DE FARMACOLOGIA APLICADA PROGRAMA ANALITICO 1. BASES PARA LA SELECCIÓN DE MEDICAMENTOS Y SU APLICACIÓN A LOS PROBLEMAS DE SALUD 1.1. Aspectos Generales 1.1.1. Uso racional de los medicamentos: concepto y propósitos. Medicamentos esenciales. Medicamentos genéricos. Formulario terapéutico. Monofármacos y asociaciones. 1