Msds en azelaic acid (june 2011 new)

1.1. Product identifier
1.2. Relevant identified uses of the substance or mixture and uses advised against
For industrial use (in the production of lacquers, polymers, pharmaceuticals, resins, polyamides etc.) 1.3. Details of the supplier of the safety data sheet
Mussenberg 1 (6049 GZ Herten-Roermond, The Netherlands)Phone +31 (0) 475 468646 Fax +31 (0) 475 468249 e-mail info@lineatrovata.nlVAT no. NL 815250733B01 (Chamber of Commerce: Limburg-Noord no. 12060481) 1.4. Emergency telephone number
0844 892 0111
24 hours per day: Only available for medical professionals
Poison information Service UK
01 809 2566
24 hours per day: Only available for medical professionals
National Poisons Information Centre Ireland
24 hours per dayAmerican Association of Poison Control Centers 2. HAZARDS IDENTIFICATION
2.1. Classification of the substance
2.1. Classification of the substance in accordance with EC/1272/2008 (CLP)
2.1. Classification of the substance in accordance with 67/548/EG (dangerous substance directive)
Xi; R36 (Irritating for the eyes), R38 (Irritating for the skin) 2.2. Label elements
H315: Causes skin irritation.
H319: Causes serious eye irritation.

P260 Do not breathe dust/ vapours. P280 Wear protective gloves & eye protection. P362 Take offcontaminated clothing and wash before reuse. P302 + P352 IF ON SKIN: Wash with plenty of soap andwater. P332 + P313 If skin irritation occurs: Get medical advice/ attention. P305 + P351 + P338 IF IN EYES:Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do.
Continue rinsing. P337 + P313 If eye irritation persists: Get medical advice/ attention.
2.3. Other hazards
Slightly flammable to flammable in presence of heat 3. COMPOSITION/INFORMATION ON INGREDIENTS
3.1. Substances
4.1. Description of first aid measures
Move the exposed person to fresh air. Keep the exposed person warm and calm. Keep theairways free. Unfasten tight clothes. If the patient isn't breathing or breathing irregular,administer artificial respiration or oxygen. Get medical attention immediately.
Flush the mouth with water. In case of dentures remove them. Move the affected person tofresh air. Keep the affected person warm and calm. Keep the airways free. Unfasten tightclothes. Seek medical advice immediately.
Skin contact
Wash the affected area with water. Remove affected clothing and shoes. Clean clothesbefore using them Eye contact
Rinse the eyes immediately for at least 15 minutes with large amounts of water, whilelifting the upper- and lower eyelids from time to time. Check for contact lenses and removethem. Burns made by chemicals should be treated by a medic immediately.
Protection of
Do not take any action if there is a chance of personal injury or in case of insufficient First aid
training. Wash out dirty clothes with water before taking them off or use gloves.
No specific treatment. Treat symptomatic. for medical

4.2. Most important symptoms and effects, both acute and delayed
Irritation of the respiratory system, coughing.
Nausea, vomiting, and diarrhea are the most likely manifestations of toxicity after ingestion Skin contact
Eye contact
4.3. Indication of any immediate medical attention and special treatment needed
5.1. Extinguishing media
SMALL FIRE: Use DRY chemical powder.
LARGE FIRE: Use water spray, fog or foam. In case of fire, keep containers cool with water spray. If a spill or leak has not ignited, use water spray to disperse the vapours. Water spray may be used to flush spillsaway from fire. 5.2. Special hazards arising from the substance or mixture
It heated, decomposition products could be one of the following: Carbon Dioxide or Carbon Monoxide.
5.3. Advice for firefighters
Fire fighters should wear proper clothing and self-contained breathing apparatus that covers the whole faceand works with a pressure mode.
6.1. Personal precautions, protective equipment and emergency procedures
No action may be taken if a chance of personal injury exists or in case of insufficient training. Put on theappropriate personal protective equipment (see section 8). Make sure unprotected and unnecessarypersonnel doesn't enter. Clean up spilled material as soon as possible according to the below mentionedprocedure. Don't inhale any of the material and avoid skin and eye contact. Make sure there's enoughventilation. 6.2. Environmental precautions
Take appropriate action to prevent spilling to the environment.
6.3. Methods and material for containment and cleaning up
Pick up spilled material and containerise for recovery or disposal. Avoid dust formation. Vacuum area withappropriate vacuum cleaner or flush with water to remove residues. 7. Handling and storage
7.1. Precautions for safe handling
Put on the appropriate personal protective equipment and take notice of hygienic measures (see section 8).
Make sure the product does not come in contact with eyes, skin or clothing. Do not inhale the dust. Do notingest any of it. Only use in well ventilated rooms/areas. Make sure eyewash stations and safety showersare as close as possible to the workplace. Avoid dust formation accumulation. Keep away from heat. 7.2. Conditions for safe storage, including any incompatibilities
Store in accordance with the local regulations in a separate, approved area. Store in original packaging,protected against direct sunlight, in a cool, well ventilated area. Keep away from heat and sources ofignition. Keep away from substances mentioned in par. 10.5. Keep the package closed and sealed until it isused. Opened packages have to be carefully closed again and kept upright to prevent leakage. Do not storein a package without label. SAFETY DATASHEET
8. Exposure controls/personal protection
8.1. Control parameters
There is no specific occupational exposure limit for Azelaic acid in the UK, IR or US.
For dust (non specific/ particulates not otherwise regulated) however there are general exposure limits:UK (COSHH): Total inhalable dust: 10 mg/m3, respirable fraction: 4 mg/m3.
IR: COP2010: Total inhalable dust: 10 mg/m3, respirable fraction: 4 mg/m3US: OSHA table Z1: Total dust: 15 mg/m3, respirable fraction: 5 mg/m3. 8.2. Exposure controls
When by the action of the user dust, smoke, gas, fume or haze arises, use a closed installation, local ventilation or other technical measures of control to keep the professional exposure below all recommended or by law required limits.
Food, drinking and smoking should be prohibited in the room where this material isprocessed. After handling chemical products wash your hands, forearms and facethorough before eating, drinking, smoking or going to the toilet and at the end of yourwork day. Wash contaminated clothes before using them again. Use dust mask (minimum P2 filter) if handling causes dust.
Wear impermeable (rubber) gloves which are resistant against chemicals and which Wear safety glasses with side shields.
9.1. Information on basic physical and chemical properties
Not flammable (the substance is combustible) SAFETY DATASHEET
10.1. Reactivity
10.2. Chemical stability
10.3. Possibility of hazardous reactions
Within normal storage circumstances and upon normal usage no dangerous reactions will occur.
10.4. Conditions to avoid
Avoid inhalation, contact with eyes or skin. Avoid dust forming. Keep away from heat, ignition sources andincompatible materials.
10.5. Incompatible materials
Avoid contact with strong acids, strong bases, oxidising and reducing substances.
10.6. Hazardous decomposition products
Within normal storage circumstances and upon normal usage no dangerous waste will be formed. It heated, thermal decomposition products could be Carbon Dioxide or Carbon Monoxide.
11.1. Information on toxicological effects
Possible acute effects on health
Acute toxicity: LD50 Oral (rat) >5000 mg/kg SAFETY DATASHEET
Possible chronic effects on health
No indication of carcinogenicity (not listed/ classified in ACGIH, IARC, NTP, OSHA,EEC).
No indication of toxicity for reproduction 12. ECOLOGICAL INFORMATION
12.1. Toxicity
LC50/ EC50 (96) > 100 mg/l (fresh water fish/ green algea): low toxicity for water organisms 12.2. Persistence and degradability
Straight chain carboxylic acids are expected to readily biodegrade 12.3. Bioaccumulative potential
The potential for bioconcentration in aquatic organisms is low (BCF < 10) 12.4. Mobility in soil
12.5. Results of PBT and vPvB assessment
12.6. Other adverse effects
13.1. Waste treatment methods
Avoid waste production, reclaim where possible. Al recovered material should be packaged, labelled,transported, and disposed or reclaimed in conformance with applicable laws and regulations and inconformance with good engineering practices. Regarding the European list of waste, (unused or undiluted)azelaic acid is to be considered as hazardous waste because of its classification as irritating. SAFETY DATASHEET
Shipping name
Class/ packing group
Not classified as dangerous for transport.
Not classified as dangerous for transport.
Not classified as dangerous for transport.
Not classified as dangerous for transport.
Not classified as dangerous for transport.
15.1. Safety, health and environmental regulations/legislation specific for the substance or mixture
National or local environmental provisions can be applicable regarding emissions to air, water or soil.
Contact the competent authority for details.
This product and/or all of its components are either included on or exempt from the US TSCA Inventory ofChemical Substances. TSCA 12(b) Components: None SARA 311/312 Hazard Categories: None SARA 313 Toxic Chemicals: None SARA 302 Extremely Hazardous Substances: None CERCLA Hazardous Chemicals: US, EPA, CERCLA Hazardous Substances (40 CFR 302) Adipic Acid CAS124-04-9 California Proposition 65: No California Proposition 65 listed chemicals are known to be present.
Al information, recommendations, and suggestions appearing herein concerning our product are basedupon tests and data believed to be reliable. However, it is the user s responsibility to determine the safety,toxicity, and suitability for his own use of the product described herein. Since the actual use by others is beyond our control, no guarantee, express or implied, is being made as to the effects of such use, theresults obtained, or the safety and toxicity of the product nor is their any assumed liability arising out of use,by others, of the product referred to herein. The information herein is not to be construed as absolutelycomplete since additional information may be necessary or desirable when particular or exceptionalconditions or cirumstances exist or because of applicable laws or government regulations.


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