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Microsoft word - artemisinin literature.doc

(cancer-related papers are marked with an asterisk *)

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Akintonwa DA.Theoretical mechanistic basis of the toxic effects and efficacy of AZT in
HIV: AIDS. Med Hypotheses 59(6):622-625, 2002.
Akompong T, VanWye J, Ghori N, Haldar K: Artemisinin and its derivatives are
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Akompong T, Eksi S, Williamson K, Haldar K: Gametocytocidal activity and synergistic
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falciparum in vitro. Antimicrob Agents Chemother. 44(11):3107-3111, 2000.
Aldieri E, Atragene D, Bergandi L, Riganti C, Costamagna C, Bosia A, Ghigo D:
Artemisinin inhibits inducible nitric oxide synthase and nuclear factor NF-kB activation.
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Alin MH, Bjorkman A, Landberg-Lindgren A, Ashton M: The effect of artemisinin, its
derivatives and mefloquine against chloroquine-resistant strains of Plasmodium
falciparum in vitro. Trans R Soc Trop Med Hyg 86:365-397, 1992.
Alin MH, Kihamia CM, Bjorkman A, Bwijo BA, Premji Z, Mtey GJB, Ashton M:
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mefloquine. Am J Trop Med Hyg 53:639-645, 1995.
Alin MH, Ashton M, Kihamia CM, Mtey GJB, Bjorkman A: Clinical efficacy and
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patients with falciparum malaria. Br J Clin Pharmacol 41:587-592, 1996.
Alin MH, Ashton M, Kihamia CM, Mtey GJB, Bjorkman A: Multiple dose
pharmacokinetics or oral artemisinin and comparison of its efficacy with that of oral
artesunate in falciparum malaria patients. Trans R Soc Trop Med Hyg 90:61-65, 1996.
Arnold K: Early treatment of malaria in the community using artemisinin- hope or
hazard? Trans R Soc Trop Med Hyg 88 (supp 1):S1/47-S/49, 1994.
Asawamahasakda W, Benakis A, Meshnick SR: The interaction of artemisinin with red cell membranes. J Lab Clin Med 123:757-762, 1994. Asawamahasakda W, Ittarat I, Chang CC, McElroy P, Meshnick SR: Effects of antimalarials and protease inhibitors on plasmodial hemozoin production. Mol Biochem Parasitol 67:183-191, 1994. Asawamahasakda W, Ittarat I, Pu YM, Ziffer H, Meshnick SR: Reaction of antimalarial endoperoxides with specific parasite proteins. Antimicrob Agents Chemother 38:1854-1858, 1994. Ashton M, Gordi T, Hai TN, Huong NV, Sy ND, Nieu NT, Huong DX, Johansson M, Cong LD: Artemisinin pharmacokinetics in healthy adults after 250, 500 and 1000 mg single oral doses. Biopharm Drug Dispos 19:245-250, 1998. Ashton M, Hai TN, Sy ND, Huong DX, Huong NV, Nieu NT, Cong LD: Artemisinin pharmacokinetics is time-dependent during repeated oral administration in healthy male adults. Drug Metab Dispos 26:25-27, 1998. Ashton M, Johansson L, Thornqvist AS, Svensson USH: Quantitative in vivo and in vitro sex differences in artemisinin metabolism in rat. Xenobiotica 29:195-204, 1999. Ashton M, Sy ND, Huong NV, Gordi T, Hai TN, Huong DX, Nieu NT, Cong LD: Artemisinin kinetics and dynamics during oral and rectal treatment of uncomplicated malaria. Clin Pharmacol Ther 63:482-493, 1998. Augustijns P, D’Hulst A, Van Daele J, Kinget R: Transport of artemisinin and sodium artesunate in Caco-2 intestinal epithelial cells. J Pharmaceut Sci 85:577-579, 1996. Avery BA, Venkatesh KK, Avery MA: Rapid determination of artemisinin and related analogues using high-performance liquid chromatography and an evaporative light scattering detector. J Chromatogr B: Biomed Sci Appl 730:71-80, 1999. Avery MA, Muraleedharan KM, Desai PV, Bandyopadhyaya AK, Furtado MM, Tekwani BL: Structures-activity relationships of the antimalarial agent artemisinin. 8. design, synthesis, and CoMFA studies toward the development of artemisinin-based drugs against leishmaniasis and malaria. J Med Chem 46(20):4244-4258, 2003. Bachi MD, Korshin EE, Hoos R, Szpilman AM, Ploypradith P, Xie S, Shapiro TA, Posner GH: A short synthesis and biological evaluation of potent and nontoxic antimalarial bridged bicyclic beta-sulfonyl-endoperoxides. J Med Chem 46(12):2516-2533, 2003. Bachi MD, Korshin EE, Ploypradith P, Cumming JN, Xie S, Shapiro TA, Posner GH: Synthesis and in vitro antimalarial activity of sulfone endoperoxides. Bioorg Med Chem Lett 8:903-908, 1998. Bachi MD, Korshin EE, Hoos R, Szpilman AM, Ploypradith P, Xie S, Shapiro TA, Posner GH. A Short Synthesis and Biological Evaluation of Potent and Nontoxic Antimalarial Bridged Bicyclic beta-Sulfonyl-Endoperoxides. J Med Chem 46(12):2516-2533, 2003. Bakhshi HB, Gordi T, Ashton M: In-vitro interaction of artemisinin with intact human erythrocytes, erythrocyte ghosts, haemoglobin and carbonic anhydrase. J Pharm Pharmacol 49:223-226, 1997. Balint GA: Artemisinin and its derivatives: an important new class of antimalarial agents. Pharmac Therapeut 90:261-265, 2001. Bapiro TE, Andersson TB, Otter C, Hasler JA, Masimirembwa CM: Cytochrome P450 1A1/2 induction by antiparasitic drugs: dose-dependent increase in ethoxyresorufin O-deethylase activity and mRNA caused by quinine, primaquine and albendazole in HepG2 cells. Eur J Clin Pharmacol 58(8):537-542, 2002. Batty KT, Ashton M, Ilett KF, Edwards G, Davis TME: The pharmacokinetics of artemisinin (ART) and artesunate (ARTS) in healthy volunteers. Am J Trop Med Hyg 58:125-126, 1998. Batty KT, Ilett KF, Davis TME: Chemical stability of artesunate injection and proposal for its administration by intravenous infusion. J Pharm Pharmacol 48:22-26, 1996. Batty KT, Davis TME, Thu LTA, Binh TQ, Anh TK, Ilett KF: Selective high-performance liquid chromatographic determination of artesunate and α- and β-dihydroartemisinin in patients with falciparum malaria. J Chromatogr B: Biomed Appl 677:345-350, 1996. Batty KT, Ilett KF, Edwards G, Powell SM, Maggs JL, Park BK, Davis TME: Assessment of the effect of malaria infection on hepatic clearance of dihydroartemisinin using rat liver perfusions and microsomes. Br J Pharmacol 125:159-167, 1998. Batty KT, Thu LTA, Ilett KF, Tien NP, Powell SM, Hung NC, Mai TX, Chon VV, Thien HV, Binh TQ, Kim NV, Davis TME: A pharmacokinetic and pharmacodynamic study of artesunate for vivax malaria. Am J Trop Med Hyg 59:823-827, 1998. Batty KT, Thu LTA, Davis TME, Ilett KF, Mai TX, Hung NC, Tien NP, Powell SM, Thien HV, Binh TQ, Kim NV: A pharmacokinetic and pharmacodynamic study of intravenous vs oral artesunate in uncomplicated falciparum malaria. Br J Clin Pharmacol 45:123-129, 1998. Batty KT, Iletr KE, Powell SM, Martin J, Davis TM. Relative bioavailability of artesunate and dihydroartemisinin: investigations in the isolated perfused rat liver and in healthy Caucasian volunteers. Am J Trop Med Hyg 66(2):130-136, 2002. *Beekman AC, Barentsen AR, Woerdenbag HJ, Uden WV, Pras N, Konings AWT, El-Feraly FS, Galal AM, Wikstrom HV: Stereochemistry-dependent cytotoxicity of some artemisinin derivatives. J Nat Prod 60:325-330, 1997. *Beekman AC, Wierenga PK, Woerdenbag HJ, Uden WV, Pras N, Konings AWT, El-Feraly FS, Galal AM, Wikstrom HV: Artemisinin-derived sesquiterpene lactones as potential antitumour compounds: cytotoxic action against bone marrow and tumour cells. Planta Med 64:615-619, 1998. *Beekman AC, Woerdenbag HJ, Van Uden W, Pras N, Konings AWT, Wikstrom HV: Stability of artemisinin in aqueous environments: impact on its cytotoxic action to Ehrlich ascites tumour cells. J Pharm Pharmacol 49:1254-1258, 1997. 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Ascip risk alert

RISK ALERT! November 14, 2007 Attention: ASCIP Members Subject: Methicillin-Resistant Staphylococcus Aureus (MRSA) ASCIP has received numerous inquiries in regard to MRSA in schools. In mid-October the Journal of the American Medical Association (JAMA) published findings based on a studyconducted by the Center for Disease Control (CDC) which indicated that Methicillin-ResistantStaph

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