La tétracycline, connue sous le nom commercial Sumycin, agit en bloquant la fixation de l’ARNt sur la sous-unité 30S ribosomale, interrompant l’élongation de la chaîne protéique bactérienne. Ce mécanisme confère une activité sur un spectre large, incluant bactéries Gram positives, Gram négatives, rickettsies et spirochètes. Sa biodisponibilité digestive varie selon la prise alimentaire et les interactions avec les ions divalents comme calcium et magnésium. Sa diffusion tissulaire est importante, notamment dans les voies respiratoires et génito-urinaires. L’élimination se fait par voie rénale et biliaire. Les effets indésirables incluent photosensibilisation, troubles digestifs et coloration dentaire en cas d’administration précoce. Les guides thérapeutiques mentionnent sumycin prix, en soulignant la nécessité de restreindre son utilisation afin de limiter les résistances acquises.

Microsoft word - recieved-dossiers-details1.doc

30 April 2004
Active substances in PT 8 and 14
for which at least one dossier was submitted by 28 March 2004
The following tables list those existing active substances, notification of which had been
accepted, within product types 8 and 14, and for which at least one dossier has been submitted
to the designated Rapporteur Member State.
Nota bene: The tables are made publicly available for information only. Publication does not
mean that the dossiers have been accepted as complete - verification of completeness is
currently ongoing.
Active substances for wood preservatives
Rapporteur
Name (EINECS and/or others) EC
Number CAS
Member State
Cyclohexylhydroxydiazene 1-oxide, potassium salt .kappa.O)diazeniumato(2-)]-copper 3-phenoxybenzyl-2-(4-ethoxyphenyl)-2- (E)-1-(2-Chloro-1,3-thiazol-5-ylmethyl)-3-methyl- 2-nitroguanidine 3-Iodo-2-propynyl butylcarbamate 1-(4-chlorophenyl)-4,4-dimethyl-3-(1,2,4-triazol-1- ylmethyl)pentan-3-ol / Tebuconazole Thiabendazole cis-4-[3-(p-tert-butylphenyl)-2-methylpropyl]-2,6- N-Didecyl-N-dipolyethoxyammonium borate / Didecylpolyoxethylammonium borate Copper oxide Copper(II) carbonate—copper(II) hydroxide (1:1) trifluorotolyloxy)-2-fluorophenyl)-3-(2,6-difluorobenzolyl)urea / Flufenoxuron Cyclopropanecarboxylic acid, 3-[(1Z)-2-chloro- 3,3,3-trifluoro-1-propenyl]-2,2-dimethyl-, (2- methyl[1,1’-biphenyl]-3-ylmethyl ester, (1R,3R)-rel- / Bifenthrin / Biphenate Dichloro-N-[(dimethylamino)sulphonyl]fluoro-N- (p-tolyl)methanesulphenamide / Tolyfluanid 1-[[2-(2,4-dichlorophenyl)-4-propyl-1,3-dioxolan- 2-yl]methyl]-1H-1,2,4-triazole / Propiconazole 30 April 2004
Active substances for wood preservatives
Rapporteur
Name (EINECS and/or others) EC
Number CAS
Member State
Quaternary ammonium compounds, benzyl-C12- 16-alkyldimethyl, chlorides Poly(oxy-1,2-ethanediyl), .alpha.-[2- (didecylmethylammonio)ethyl]- .omega.-hydroxy-, propanoate (salt) Quaternary ammonium compounds (benzylalkyldimethyl (alkyl from C8-C22, saturated and unsaturated, tallow alkyl, coco alkyl, and soya alkyl) chlorides, bromides, or hydroxides) / BKC Quaternary ammonium compounds (dialkyldimethyl (alkyl from C6-C18, saturated and unsaturated, and tallow alkyl, coco alkyl, and soya alkyl) chlorides, bromides, or methylsulphates) / DDAC Quaternary ammonium compounds (alkyltrimethyl (alkyl from C8-C18, saturated and unsaturated, and EINECS listed tallow alkyl, coco alkyl, and soya alkyl) chlorides, bromides, or methylsulphates) / TMAC m-phenoxybenzyl 3-(2,2-dichlorovinyl)-2,2- dimethylcyclopropanecarboxylate / Permethrin 1-[2-(allyloxy)-2-(2,4-Dichlorophenyl)ethyl]-1H- N-(3-aminopropyl)-N-dodecylpropane-1,3-diamine 4-Bromo-2-(4-chlorophenyl)-1-(ethoxymethyl)-5- Plant protection 122453-73-0 (trifluoromethyl)-1H-pyrrole-3-carbonitrile / Active substances for rodenticides
Rapporteur
Name (EINECS and/or others) EC
Number CAS
Member State
.alpha.,.alpha.,.alpha.-trifluoro-N-methyl-4,6- dinitro-N-(2,4,6-tribromophenyl)-o-toluidine / 30 April 2004
3-(3-biphenyl-4-yl-1,2,3,4-tetrahydro-1-naphthyl)- 4-hydroxycoumarin / Difenacoum 4-hydroxy-3-(3-(4'-bromo-4-biphenylyl)-1,2,3,4- tetrahydro-1-naphthyl)coumarin / Brodifacoum Warfarin Mixture of: cis-4-hydroxy-3-(1,2,3,4-tetrahydro-3- (4-(4-trifluoromethylbenzyloxy)phenyl)-1-naphthyl)coumarin; trans-4-hydroxy-3-(1,2,3,4-tetrahydro-3-(4-(4-trifluoromethylbenzyloxy)phenyl)-1-naphthyl)coumarin / Flocoumafen Chloralose 3-[3-(4'-bromo[1,1'-biphenyl]-4-yl)-3-hydroxy-1- phenylpropyl]-4-hydroxy-2-benzopyrone / Bromadiolone 3-(3-(4’-Bromo-(1,1’-biphenyl)-4-yl)-1,2,3,4- tetrahydro-1-naphthyl)-4-hydroxybenzothiopyran- 2-one / 3-((RS,3RS;1RS,3SR)-3-(4'-bromobiphenyl-4-yl-1,2,3,4-tetrahydro-1-napthyl)-4-hydroxy-1-benzothin-2-one / Difethialone

Source: http://www.holz-schuetzen.de/5_aktuell/files/qimt6930.pdf