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Climacteric. 2007 Jun;10(3):264; author reply 264-5. Applied relaxation and oral estradiol treatment of vasomotor symptoms in postmenopausal women.
Effects of acupuncture, applied relaxation, estrogens and placebo on hot flushes in
postmenopausal women: an analysis of two prospective, parallel, randomized

A comparison of acupuncture and oral estradiol treatment of studies.
Vasomotor symptoms decrease in women with breast cancer Zaborowska E, Brynhildsen J, Damberg S, Fredriksson M, Lindh-Astrand L,
randomized to treatment with applied relaxation or electro- Nedstrand E, Wyon Y, Hammar M.
Division of Obstetrics and Gynecology, Department of Molecular and Clinical Medicine, Faculty Review Phytoestrogens for vasomotor menopausal of Health Sciences, University Hospital, Linköping, Sweden. OBJECTIVE: To assess if transdermal or oral estrogens, acupuncture and applied Review [Few alternatives to estrogen replacement therapy relaxation decrease the number of menopausal hot flushes/24 h and improve climacteric symptoms, as assessed by the Kupperman index, more than transdermal placebo treatment. SETTING: An outpatient clinic at a Swedish university hospital. METHODS: A total of 102 postmenopausal women were recruited to two studies performed in parallel. In Study I, the women were randomized between transdermal Patient Drug Information
placebo or estrogen treatment and, in Study II, between oral estrogens, Estrogen (Cenestin® , Enjuvia® , Estrace® , .) Estrogen acupuncture or applied relaxation for 12 weeks. Climacteric symptoms were is used to treat hot flushes ('hot flashes'; sudden strong measured with daily logbooks on hot flushes. Women completed the assessment feelings of heat and sweating) in women who are questionnaire for the Kupperman index at baseline and after 12 weeks. RESULTS: experiencing menopause ('change of life', the end of The number of flushes/24 h decreased significantly after 4 and 12 weeks in all monthly menstrual periods). Some brands of estrogen. groups except the placebo group. Both at 4 and 12 weeks, acupuncture decreased the number of flushes more (p<0.05; p<0.01, respectively) than placebo. At 12 weeks, applied relaxation decreased the number of flushes more (p<0.05) than placebo. The Kupperman index score decreased in all groups except the placebo group. The decrease in score was significantly greater in all treatment groups than Recent Activity
in the placebo group (p<0.01). CONCLUSION: Acupuncture and applied relaxation both reduced the number of hot flushes significantly better than placebo and should be further evaluated as alternatives to hormone therapy in women with menopausal vasomotor complaints. Effects of acupuncture, applied relaxation, estrogens and placebo on hot flushes in postme. PMID: 17364603 [PubMed - indexed for MEDLINE] Effects of acupuncture and estrogens on hot flushes. Acupuncture in managing menopausal symptoms: hope or mirage? A randomized, controlled pilot study of acupuncture treatment for menopausal hot flashes. Study Protocol: effects of acupuncture on hot flushes in perimenopausal and postmenopausal. Department of Health & Human Services Privacy Statement | Freedom of Information Act | Disclaimer http://www.ncbi.nlm.nih.gov/pubmed/17364603?ordinalpos=21&itool=EntrezSystem. 12/02/2009

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