YEAST CULTURE DAIRY RESEARCH REPORT 1992-1 PRODUCTION RESPONSE OF DAIRY COWS TO SUPPLEMENTAL YEAST CULTURE DURING EARLY LACTATION
Table 1. Nutrient analysis of experimental diets and
Effects of supplemental Yeast Culture on yield and
composition of milk during early lactation were evaluated
with six primiparous and 12 multiparous Holstein cows.
Total mixed rations fed behind Calan gates contained
41.7% corn silage and 58.3% concentrate (DM basis)
----------------------- % DM ----------------------
without (Control) or with Yeast Culture substituted for .7% CP
of DM. A preliminary period during the first 2 wk ADF
postpartum was followed by an 11 wk experimental NDF
period. Cows were milked twice daily and milk samples Lignin
were taken on two consecutive days at the end of the wk Ca
of the preliminary period and wk 3, 6, 9, and 11 of the P
experimental period. Addition of yeast culture to the diet Mg
tended to increase yields of milk and 3.5% Fat Corrected
Milk but reduced percentages of milk lactose and Solids NEC,
Non-Fat. Efficiency of production was increased from
1.30 to 1.42 lb milk/lb dry matter intake and income over UIPC,
feed cost was $.55/cow/day higher when Yeast Culture
A Diamond V Yeast Culture, Diamond V Mills, Inc.,
Materials and methods
B Composition of concentrate (% DM basis): ground
corn 33.27, wheat middlings 20.39, soybean meal
Six primiparous and 12 multiparous Holstein cows were
(48%) 2.42, cottonseed meal (41%) 30.96, meat &
assigned to one of two treatments at parturition based on
bone meal 7.10, limestone 2.43, magnesium oxide
parity and previous treatment in a randomized block
.83, sodium bicarbonate 1.21, Dynamate 1.07, salt
design. The control diet composed of 41.7% corn silage
.09, premix .23. (Premix: 1.5% Fe, 2.7% Zn, 1.5%
and 58.3% (DM basis) concentrate (Table 1) and was fed
Mn, 4,000 ppm Cu, 115 ppm Co, 300 ppm I, 265 ppm
as a total mixed ration (TMR) twice daily behind Calan
Se, 2,000,000 IU/kg Vitamin A, 900,000 IU/kg Vitamin
gates (American Calan Inc., Norwood, NH) for ad libitum C Calculated using values from NRC.
consumption. After a 2 wk preliminary period, Yeast
Culture (Diamond V Mills, Inc., Cedar Rapids, IA) was
substituted for .7% of control TMR DM. Data and Milk yield was recorded at each milking and averaged for
samples were collected for the following 11 weeks of each wk. Milk samples were collected from each of the
last four consecutive milkings of wk 2 of the preliminary
period and wk 3, 6 and 9 of the experimental period.
Samples of corn silage, concentrate and refusal were Samples were composited by cow each wk and shipped
taken daily and dried at 60°C for 48 hr in a forced air oven to Virginia DHIA for analysis of milk fat, protein, lactose
for determination of DM concentrations. Daily samples and SNF concentrations.
were ground using a Wiley mill (Arthur H. Thomas,
Philadelphia, PA) to pass through a 1 mm screen and Data were analyzed as a split plot design using general
analyzed for CP, NDF, ADF, 72% sulfuric acid lignin, Ca, linear model procedures of SAS. The statistical model
P, K, and Mg. Concentrations of undegraded intake used for the analysis of covariance was:
protein and NE were calculated using NRC values. Table 2. Intake and production response of cows fed TMR with or without supplemental Yeast Culture. DMI, lb/d
C(T) = effect of cow nested within treatment i,
Milk, lb/d Fat, lb/d 3.5% FCM, lb/d Protein, %
Preliminary DMI (for DMI analysis) and FCM (for production Protein, lb/d
analysis) were used as covariates. Cow nested within Lactose, %
treatment was used as the error term for testing treatment Lactose, lb/d
effects. All other independent variables were tested SNF, % SNF, lb/d Results and discussion
lb FCM/lb DMI for control and Yeast Culture, respectively.
Based on chemical analysis of diet ingredients and TMR Increased milk yield has been reported for cows fed Yeast
(Table 2), diets provided adequate amounts of nutrients to Culture during early lactation and for high producing
support milk yield observed throughout the trial. Dry groups, but not for cows in mid- lactation or in low
matter intake was not different (P=.56) among cows fed producing groups. In contrast to results of the current
control or Yeast Culture supplemented diets. This is in trial, increased percent milk fat and milk protein and/or
agreement with observations of other researchers.
decreased milk protein have been reported when Yeast
Although not significantly different, yield of milk and 3.5%
FCM were 12.1% (P=.24) and 9.6% (P= .20) higher for Differences in nutrient intake cannot explain the observed
cows fed diets with Yeast Culture. These numeric trends in milk and 3.5% FCM yield as cows consumed
differences in milk yield were evident at wk 2 of the equal amounts of DM and nutrients based on chemical
experimental period and continued throughout the analysis of TMR. Supplemental Yeast Culture apparently
remainder of the trial as illustrated in Figure 1. Milk increased utilization of nutrients, possibly through altering
composition was not different among cows due to ruminal fermentation as discussed previously.
treatment although percent milk lactose and SNF tended
to be lower (P = .13 and .21, respectively) for cows fed Conclusions
Yeast Culture. Efficiency of milk production was not
different between treatments and averaged 1.30 and 1.44 Dry matter intake, milk yield and milk composition were
not significantly different among cows consuming TMR
Figure 1. Effect of Yeast Culture on milk yield.
diets with or without Yeast Culture during early lactation
although milk yield of cows fed the Yeast Culture tended
to be higher throughout the trial. Based on increased
feed cost of $.07 per cow due to Yeast Culture, income
over feed cost was increased $.55 per cow per day by
supplemental Yeast Culture when 3.5% fat milk was
priced at $10 per cwt. Additional research is needed to
determine the effect of Yeast Culture on nutrient utilization
Research source
J.K. Bernard and F.M. Kelly, 1992, Department of Animal
Science, Agricultural Experiment Station, The University
Figure 1. Effect of Yeast Culture on milk yield.
This is an illustrative guide to the cytochrome P450 contribution to drug interactions likely for medication pairs that are substrates, inhibitors or inducers of the same enzyme. More than one-half of patients also carry genetic variations in CYP 1A2, 2C9, 2C19, and 2D6 genes that can dramatically alter patient drug exposures, and for which DNA testing can be ordered. The GeneMedRx drug int
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