Dbtindia.gov.in

Annexure - VII
PUBLICATIONS / PATENTS OF DBT AUTONOMOUS INSTITUTES
DURING 2004-2005
NATIONAL INSTITUTE OF IMMUNOLOGY, NEW DELHI
Impact
factor
Enzymic activation and transfer of fatty acids as acyl-adenylates in mycobacteria.
Trivedi OA, Arora P, Sridharan V, Tickoo R,Mohanty D and Gokhale RS, (2004).
Inducible nitric oxide synthase in T cells regulates T cell death and immune memory.
Vig M, Srivastava S, Kandpal U, Sade H,Lewis V, Sarin A, George A, Bal V,Durdik JM, Rath S, (2004).
polyketide synthase reveals the structural basis for generating diverse metabolites.
Sankaranarayanan R, Saxena P, Marathe UB,Gokhale RS, Shanmugam VM, Rukmini R.A, (2004).
Vi polysaccharide of Salmonella typhi targets the prohibitin family of molecules in intestinal epithelial cells and suppresses early inflammatoryresponses.
Sharma A, Qadri A, (2004).
Pleiotropic consequences of Bruton tyrosine kinase deficiency in myeloid lineages lead topoor inflammatory responses.
Mangla A, Khare A, Vineeth V, Panday NN,Mukhopadhyay A, Ravindran B, Bal V, George A,Rath S, (2004).
Complex phenotypes in an Indian family with homozygous SCA2 mutations.
Ragothaman M, Sarangmath N, Chaudhary S, Khare V,Mittal U, Sharma S, Komatireddy S, Chakrabarti S,Mukerji M, Juyal RC, Thelma BK, Muthane UB, (2004).
The pathway for MHCII-mediated presentation of endogenous proteins involves peptide transport to theendo-lysosomal compartment.
Dani A, Chaudhry A, Mukherjee P, Rajagopal D,Bhatia S, George A, Bal V, Rath S, Mayor S, (2004).
Plasticity within the antigen-combining site may manifest as molecular mimicry in the humoral immune response.
Goel M, Krishnan L, Kaur S, Kaur KJ, Salunke DM,(2004).
Analysis of mutational lineage trees from sites of primary and secondary Ig gene diversification in rabbits and Annexures
Impact
factor
chickens.
Mehr R, Edelman H, Sehgal D, Mage R, (2004).
NRPS-PKS: a knowledge-based resource for analysis Ansari MZ, Yadav G, Gokhale RS, Mohanty D, (2004).
pH and cation induced thermodynamic stability of human hyaluronan binding protein 1 regulates its hyaluronan affinity.
Jha BK, Mitra M, Rana R, Surolia A, Salunke DMand Datta K, (2004).
PfPKB, a novel protein kinase B like enzyme from Plasmodium falciparum:I. Identification,characterization and possible role in parasite development.
Kumar A, Vaid A, Syin C and Sharma P, (2004).
Apoptotic death in Leishmania donovani promastigotes in response to respiratory chain inhibition: complex IIinhibition results in increased pentamidine cytotoxicityMehta A and Shaha C, (2004).
Linkage of interactions in sickle hemoglobin fiber assembly: Inhibitory effect emanating frommutations in the AB region of the a-chain isannulled by a mutation at its EF corner.
Sudha R, Anantharaman L, Sivaram MV, Mirsamadi N,Choudhury D, Lohiya NK, Gupta RB and Roy RP, (2004).
Parathyroid hormone gene polymorphism and sporadic idiopathic hypoparathyroidism.
Goswami R, Mohapatra T, Gupta N, Rani R, TomarN, Dikshit A, Sharma RK, (2004).
Degeneration of stroma reduces retention of homed Stem Cells Dev 13:173-82.
cells in bone marrow of lethally irradiated mice.
Madhusadan T, Mazumdar S and Mukhopadhyay A,(2004).
Novel label-free DNA sensors based on poly (3,4-ethylenedioxythiophene).
Krishnamoorthy K, Gokhale RS, Contractor AQ andKumar A, (2004).
An additional copy of the homologous region (hr1) sequence in the Autographa californica multinucleocapsid polyhedrosis virus genomepromotes hyperexpression of foreign genes.
Venkaiah B, Viswanathan P, Habib S, Hasnain SE,(2004).
Oral tolerance in T cells is accompanied by induction of effector function in lymphoid organs after systemicimmunization.
Parameswaran N, Samuvel DJ, Kumar R, Thatai S,Bal V, Rath S, George A, (2004).
DBT Annual Report 2004 - 2005
Impact
factor
Oral immunization of mice with Japanese encephalitis virus envelope protein synthesized in Escherichiacoli induces anti-viral antibodies.
Rauthan M, Kaur R, Appaiahgari MB, Vrati S, (2004).
Demonstration that mast cells, T cells, and B cells bearing the activating kit mutation D816V occur in clusters within the marrow of patients with mastocytosis.
Taylor ML, Sehgal D, Raffeld M, Obiakor H, Akin C,Mage RG, Metcalfe DD. (2004) Rescue of TNFalpha-inhibited neuronal cells by IGF-1 involves Akt and c-Jun N-terminal kinases.
Kenchappa P, Yadav A, Singh G, Nandana S,Banerjee K, (2004).
Immunogenicity and protective efficacy in mice of a formaldehyde-inactivated Indian strain of Japanese encephalitis virus grown in Vero cells.
Appaiahgari MB, Vrati S, (2004).
Immunogenicity in mice of a cationic microparticle- adsorbed plasmid DNA encoding Japanese encephalitisvirus envelope protein.
Kaur R, Rauthan M, Vrati S, (2004).
Prevalence of calcium sensing receptor autoantibodies in patients with sporadic idiopathic hypoparathyroidism.
Goswami R, Brown EM, Kochupillai N, Gupta N,Rani R, Kifor O, Chattopadhyay N, (2004).
Characterization and evaluation of chitosan matrix for in vitro growth of MCF-7 breast cancer cell lines.
Dhiman HK, Ray AK and Panda AK, (2004).
Isolation and characterization of a haploid germ cell specific sperm associated antigen 9 (SPAG9) fromthe baboon.
Shankar S, Mohapatra B, Verma S, Selvi R,Jagadish N, Suri A, (2004).
Update on zona pellucida glycoproteins based Gupta SK, Srivastava N, Choudhury S, Rath A,Sivapurapu N, Gahlay GK, Batra D, (2004).
A facile and novel route to the antigenic branched phosphoglycan of the protozoan Leishmania major parasite.
Ruhela D and Vishwakarma RA, (2004).
Porphyrin binding to jacalin is facilitated by the inherent plasticity of the carbohydrate binding site: Crystallogr. 60:281-288.
novel mode of lectin-ligand interaction.
Goel M, Anuradha P, Kaur KJ, Maiya BG,Swamy MJ and Salunke DM, (2004).
Annexures
Impact
factor
Purification, identification and preliminary crystallographic characterization of a novel seed Chanana V, Kaur KJ, Salunke DM, (2004).
Crystallization and preliminary x-ray crystallographic investigations of an unusual type III polyketide synthase PKS18 from Mycobacterium tuberculosis.
Rukmini R, Sanmugam VM, Saxena P, Gokhale RSand Sankaranarayanan R, (2004).
Molecular cloning, expression of testicular transcript abundant in germ cells and immunobiological effects of the recombinant protein.
Verma S, Mohapatra B, Jagadish N, Selvi R, Roy P,Rana R, Lakshmi K, Suri A, (2004).
Japanese encephalitis virus (JEV) is an important cause of encephalitis among children in Cuddaloredistrict,TamilNadu,India.
Kabilan L, Vrati S, Ramesh S, Srinivasan S,Appaiahgari MB, Arunachalam N, Thenmozhi V,Kumaravel SM, Samuel PP, Rajendran R, (2004).
Fibroin silk proteins from the nonmulberry silkworm Philosamia ricini are biochemically andimmunochemically distinct from those of the mulberrysilkworm Bombyx mori.
Ahmad R, Kamra A, Hasnain SE, (2004).
Expression of protooncogene c-kit receptor in rat testis and uniqueness of extracellular domain acrossthe species with potential in molecular phylogeny.
Prasanth SG, Chattopadhyay M, Bhat KV, Ali S,(2004).
Organizational variation of DYZ1 repeat sequences on the human Y chromosome and its diagnosticpotentials.
Rahman MM, Bashamboo A, Prasad A, Pathak D,Ali S, (2004).
Molecular basis of predisposition to develop type 1 Purification, refolding, and characterization of Raina K, Panda AK, Ali MM, Talwar GP. (2004).
Studies on the immunogenic potential of plant- expressed cholera toxin B subunit.
Jani D, Singh NK, Bhattacharya S, Meena LS,Singh Y, Upadhyay SN, Sharma AK, Tyagi AK.
(2004) Sebaceous gland adenoma in a rhesus monkey DBT Annual Report 2004 - 2005
Impact
factor
Mahesh Kumar MJ, Nagarajan P, Venkatesan R,Sakthivelan SM, Majumdar SS, (2004).
A 1.3 kb satellite DNA from Bubalus bubalis not conserved evolutionarily is transcribed.
Bhatnagar S, Bashamboo A, Chattopadhyay M,Gangadharan S, Ali S. (2004) Diversity & overlap in the mechanisms of processing protein antigens for presentation to T cells.
Rajagopal D, Bal V, George A, Rath S, (2004).
In vitro selected RNA-cleaving DNA enzymes from Chakraborti S, Sriram B, Banerjea AC, (2004).
Cytotoxicity of in vitro produced Podophylotoxin from P.hexandrum cell culture on human cancer cell line.
Chatopadhyay S, Srivastava AK, Panda AK andBisaria VS, (2004).
Sequence specific cleavage activities of DNA- enzymes targeted against HIV-1 Gag and Nef regions.
Macaca radiata females by bromocriptine under laboratory conditions.
Nagarajan P, Venkatesan R, Mahesh Kumar MJand Majumdar SS (2004) X RNA in cis and trans by novel monotarget and multitarget hammerhead motif-containingribozymes.
Goila R, Banerjea AC, (2004).
Hematopoietic stem cells: clinical requirements and Mukhopadhyay A, Madhusudhan T, Kumar R, (2004).
Sperm specific proteins-potential candidate molecules Dissecting the Mechanism and Assembly of a Complex Virulence Mycobacterial Lipid.
Trivedi OA, Arora P, Vats A, Ansari MZ, Tickoo R,Sridharan V, Mohanty D, Gokhale RS, (2005).
Hemoglobin Receptor in Leishmania Is a Hexokinase Krishnamurthy G, Vikram R, Singh SB, Patel N,Agarwal S, Mukhopadhyay G, Basu SK,Mukhopadhyay A, (2005).
Estrogen-induced Spermatogenic Cell Apoptosis Annexures
Impact
factor
Role of Superoxide and Nitric OxideMishra DP, Shaha C, (2005).
glycosylphosphatidylinositols of parasitic protozoa and [4-deoxy-Man-III]-GPI analogues.
Ali A, Gowda DC, Vishwakarma RA, (2005).
Vishwakarma RA, Menon AK, (2005). Flip-flop of glycosylphosphatidylinositols (GPI’s) across the ER.
Crystal Structures of PNA-Porphyrin Complex in the Presence and Absence of Lactose: Mapping theConformational Changes on Lactose Binding,Interacting Surfaces and Supramolecular Aggregations.
Goel M, Damai RS, Sethi DK, Kaur KJ, Maiya BG,Swamy, MJ, Salunke DM (2005) Fate of SRY, PABY, DYS1, DYZ3 and DYZ1 loci in Indian patients harbouring sex chromosomal anomalies.
Bashamboo A, Rahman MM, Prasad A, Chandy SP,Ahmad J, Ali S, (2005).
Three-dimensional chitosan scaffold-based MCF-7 cell culture for the determination of the cytotoxicity of tamoxifen.
Dhiman HK, Ray AR, Panda AK, (2005).
Efficacy of antibodies against a chimeric synthetic peptide encompassing epitopes of bonnet monkey (Macaca radiata) zona pellucida-1 and zonapellucida-3 glycoproteins to inhibit in vitro humansperm-egg binding.
Sivapurapu N, Hasegawa A, Gahlay GK, Koyama K,Gupta SK, (2005).
Upregulation of Glut-4 and PPARgamma by an isoflavone from Pterocarpus marsupium on L6 myotubes: a possible mechanism of action.
Anandharajan R, Pathmanathan K, ShankernarayananNP, Vishwakarma RA, Balakrishnan A, (2005).
1-Oxabicyclic b-lactams as new inhibitors of elongating MPT–a key enzyme responsible for assembly of cell-surface phosphoglycans of Leishmania parasite.
Ruhela D, Chatterjee P, Vishwakarma RA, (2005).
New fluorescent probes reveal that flippase-mediated flip-flop of Phosphatidylinositol across the ER membrane does not depend on the stereochemistry of the lipid.
Vishwakarma RA, Vehring S, Mehta A, Sinha A,Pomorski T, Herrmann A, Menon AK, (2005).
DBT Annual Report 2004 - 2005
NATIONAL CENTRE FOR CELL SCIENCE, PUNE
Impact
factor
Reciprocal CD40 Signals through P38MAPK and ERK- 1/2 induce counteracting immune reponses.
Mathur R.K.; Awasthi A.; Washone P.; Ramanamurthy B.; Stem and progenitor like cells contribute to the aggressive behaviour of human epithelial ovarian Kurrey N. K., Amit K and Bapat S. A.
Displacement of SATB1-bound HDAC1 corepressor by HIV-1 transactivator induces expression of Interleukin-2 Pavan Kumar P., Prabhat Kumar Purbey, Dyavar S. Ravi, Debashis Mitra and Sanjeev Galande. (2005) HIV-1 Tat directly binds to NFkB enhancer sequence: role in viral and cellular gene expression.
Dandekar D.H.; Ganesh K.N.; Mitra D. (2004) SMAR1 and Cux/CDP modulate chromatin and act as negative regulators of the TCRb enhancer (Eb).
Kaul-Ghanekar R.; Jalota A.; Pavithra L.; Chattopadhyay Osteopontin Induces AP-1-mediated Secretion of Urokinase-type Plasminogen Activator through c-Src- dependent Epidermal Growth Factor ReceptorTransactivation in Breast Cancer Cells Riku Das.; Mahabeleshwar G.H.; Kundu G.C. (2004) Tyrosine Kinase, p56lck-induced Cell Motility, and Urokinase-type Plasminogen Activator Secretion Involve Activation of Epidermal Growth Factor Receptor/Extracellular Signal Regulated Kinase Pathways Mahabeleshwar G.H.; Das R.; Kundu G.C. (2004) Regulation of murine cytochrome c oxidase Vb gene expression during myogenesis: YY1 and a CArG bindingprotein reciprocally regulate the transcription activity byphysical interaction with BERF-1/ZBP-89 factor.
Ettickan B.; Lenka N.; Prabu S.K.; Fang J.K.; Wilkinson F.; Atchison M.; Giallongo A.; Avadhani N.G. (2004) Nuclear factor inducing kinase plays crucial role in osteopontin induced MAPK/IKK dependent nuclear factor kB-mediated promatrix metalloproteinase-9activation.
Annexures
Impact
factor
Interleukin-3 and granulocyte-macrophage colony- stimulating factor inhibits tumor necrosis factor- -induced (In press).
osteoclast differentiation by down-regulation of TNFR1and TNFR2 expression.
S. D. Yogesha, Shruti M. Khapli, and Mohan R. Wani Tumor suppressor SMAR1 activates and stabilizes p53 through its arginine-serine (RS) rich motif.
Archana Jalota, Kamini Singh, L Pavithra, Ruchika Kaul, Shahid Jameel, and Samit Chattopadhyay (2005) Abnormal V(D)J recombination of T cell receptor ? locus J. Biol. Chem, May, 10. 1074.
Kaul-Ghanekar, R., Majumdar, S., Jalota., A., Gulati, N., Dubey, N., Saha B. and Chattopadhyay, S. (2005) Kinetic analysis of the interactions between vaccinia virus complement control protein and human complement Bernet J.; Mullick J.; Panse Y.; Parab P.B.; Sahu A. (2004) Identification of functional domains in daposica, the complement control protein homolog of kaposi’s sarcoma- (In Press).
associated herpesvirus (human herpesvirus-8).
Mullick J, Singh A. K, Panse Y, Yadav V, Bernet J and Salunke D.B; Hazra B.J.; Pore V.S.; Bhat M.K.; Nahar Slow-tight binding inhibition of enoyl-acyl carrier protein reductase from Plasmodium falciparum by triclosan.
Kapoor M.; Reddy C.C.; Krishnasastry M.V.; Surolia N.; Analysis of morphological and functional maturation of neoislets generated in vitro form pancreatic ductal cellsand their suitability for islet banking and transplantation.
Katdare M.R.; Bhonde R.R.; Parab P.B. (2004) Characterization of the interaction of Complement receptor 2 with its Ligands and EBV glycoprotein gp350/ Sarrias M.R.; Sahu A.; Lambris J.D. (2004) Insulin-secretagogue activity and cytoprotective role of the traditional antidiabetic plant Scoparia dulcis (Sweet Muniappan L; Pari L.; Sitasawad S.;Bhonde R.R. (2004).
DBT Annual Report 2004 - 2005
Impact
factor
Carboplatin induces apoptotic cell death through downregulation of constitutive activity of nuclear factor- kB in human HPV-18 E6 positive HEp-2 cells.
Synthesis, structural characterization and evaluation of insulin-mimetic potential of bis (quercetinato) Shukla R.; Barve V.; Padhye S.; Bhonde R.R. (2004).
Molecular mechanisms behind the dose dependent differential activation of MAPK pathways induced by Matrix B-mediated activation and?metalloproteinase-2: mechanism and regulation of NF- its role in cell motility The Selenophosphatase gene from Leishmania major.
Jaykumar P.C.; Musande V.; Shouche Y.S.; Patole M.S.
Comparison of 16S rRNA gene sequences of genus Dighe A.S.; Jangid K.; Gonzalez J.M.; Pidiyar V.J.; Patole M.S.; Ranade D.R.; Shouche Y.S.; (2004) Studies on cultured and uncultured microbiota of wild Culex quinquefasciatus mosquito midgut based on 16S Pidiyar V.J.; Jangid K.; Patole M.S.; Shouche Y.S.
Methanobrevibacter: Is it a potential pathogen.
Current Science 86: 1475-1476.
Jangid K.; Rastogi G.; Patole M.S.; Shouche Y.S. (2004) The cag pathogenicity island (cag-PAI) of Helicobacter pylori is disrupted in majority of patient isolates from Kauser F.; Khan A.A.; Hussain M.A.; Carroll I.M.; Ahmad N.; Tiwari S.; Shouche Y.S.; Das B.;Jyothirmayee C.S.; Alam M.; Ali M.; Habibullah S.;Sierra C.M.; Megraud F.; Sechi L.A.; Ahmed N. (2004) Capillaria hepatica infection in bandicoot rat (Bandicota Raut C.G.; Gengaje B.B.; Nipunage S.V.; Rajarshi M.P.; Vaidya S.R.; Rane, S.R.; Pol S.S.; Kohale K.N. (2003) Annexures
Impact
factor
Species determination and authentication of meat samples by mitochondrial 12S rRNA gene sequence analysis andconformation sensitive gel electrophoresis.
Rastogi G.; Bharde A.; Dharne M.; Pandav V.S.; Ghumatkar S.V.; Shinde B.M.; Patole M.S.; Shouche Y.S.
(2004) HIV-1 integration sites are flanked by potential MARs that Biochemical Biophysical Kulkarni A.; Pavithra L.; Rampalli, S.; Mogare D.; Babu K.; Shiekh G.; Ghosh, S.; Chattopadhyay S.; (2004) Modulation of Cytokine Profiles by Malaria Pigment- Hemozoin and Role of IL-10 in Suppression ofProliferative Responses of Mitogen Stimulated HumanPBMC.
Caveolin-1 binding motif of alpha-hemolysin: its role in Pany S.; Vijayvargia R.; Krishnasastry M. V. (2004) Doxycycline Potentiates Antitumor Effect of Chhipa R.R.; Singh S.; Surve S.V.; Vijayakumar M.V.; Widespread Occurrence Of The Plasmodium Falciparum Chloroquine Resistance Transporter (Pfcrt) Gene Haplotype Svmnt In P. Falciparum Malaria In India Vathsala P.G.; Pramanik A.; Dhanasekaran S.; Usha Devi C.; Pillai C.T.;Subbarao S.K.; Ghosh S.K.; Tiwari S.N.;Sathyanarayan T.S.; Deshpande P.R.; Mishra G.C.; RanjitM.R.; Dash A.P.; Rangarajan P.N.; Padmanaban G. (2004) Assembly of á-hemolysin on A431 cells leads to clustering Vijayvargia R, Kaur S, Sangha N, Sahastrabuddhe A, Surolia A, Shouche Y and Krishnasastry M. V. (2004).
Functional form of caveolin-1 is necessary for the Vijayvargia R, Suresh G. C and Krishnasastry M. V.
Staphylococcal á-HL induced dephosphorylation of EGF receptor of A431 cells is carried out by receptor like Vijayvargia R, Kaur S and Krishnasastry M. V . (2004).
‘Reversal of experimental diabetes by multiple bone Banerjee M., Kumar A. and Bhonde RR.
DBT Annual Report 2004 - 2005
Impact
factor
GST fusion vector with caspase-6 cleavage site for removal of fusion tag during column purification.
(2005).
Prabhat Kumar Purbey, P. Cyril Jayakumar, P. D.
Deepalakshmi, MilindS. Patole and Sanjeev Galande Snail and Slug are major determinants of ovarian cancer invasiveness at the transcription level. (2005).
Kurrey N. K., Amit K and Bapat S. A.
Studies on recombinant single chain jacalin lectin reveal loss of affinity for saccharides despite normal folding likenative Jacalin.
Sahstrabuddhe A, Gaikwad S. M, Krishnasastry M. V and A combination of catalase and trehalose as additives in the conventional freezing medium results in improvedcryoprotection of human hematopoietic cells withreference to in vitro migration and adhesion properties.
Lalita M. Sasnoor, Vaijayanti P. Kale and Lalita S.
Doxycycline potentiates antitumor effect of Chippa R. R, Singh S, Surve S. V, Vijaykumar M. V and ‘Islet ontogeny determines glucose responsiveness’.
HIV-1 Tat Modulates T-bet Expression and Induces Th1 Kulkarni, A. Ravi D. S., Singh K, Rampalli S., Parekh V., PATENTS GRANTED
Wani M. R, Parab. P. B., Chatterji A. (2003) Pharmaceutical composition useful for inhibition ofosteoclast formation and a process for the extraction ofmussel hydrolysate from Indian green mussel (PemaViridis). US patent # 09/944, 497, Joint Patent, NationalCentre for Cell Science, Pune and National Institute ofOceanography, Goa.
K. V. S. Rao, Mohan R. Wani, V. Manivel, P. S.
Parmeswaran, V. K. Singh, R. V. Anand, E.Desa, G. C.
Mishra, A. Chatterji. Novel molecules to develop drugfor the treatment of osteoporosis. US Patent # 10/747,671.
Annexures
PATENTS SUBMITTED / FILED
One US patent filed jointly with NCL “ Bile acid derived steroidal dimmers with amphiphilic topology havingantiproliferative activity” Parab P. B. and Chatterji A. (2002).Radioprotective activity from an extract from Indian green mussel (Pernaviridis) Patent submitted (2002) Joint patent – National Centre for Cell Science, Pune and National Institute of Oceanography, Goa.
Process for the identification of insulin producing ??cells proliferating factor from the perivitelline fluid of fertilizedeggs of the Indian horseshoe crab. Patent submitted (2002) Joint patent – National Centre for Cell Science, Pune and National Institute of Oceanography, Goa.
Monoclonal antibody against costimulatory molecule (m150) and the process for preparation.
Patent submitted (2003) Provisional patent registration No. 30,480 dated 14.08.2003. National Centre for CellScience, Pune D.V.R. Prasad, P. B. Parab and G. C. Mishra (2003) Cardiac development promoting activity in perivitelline fluid of embryos of Indian horseshoe crab. Patentapplication under preparation (2004) Ghaskadbi S.M., Parab P. B., Chatterji A., Patwardhan V.
Methods to create a composition in vitro, capable of acting as an artificial bone marrow like environment (ABME),which can be used to stimulate blood cell formation Metalloantidiabetics: An Oral Vanadium Conjugate , # A composition for promoting growth of pancreatic cells.
Dr. R. R. Bhonde & Dr. S. A. Galande An improved expression system.
Galande S. A., Purbey P., Jayakumar C., Patole M. S.
DBT Annual Report 2004 - 2005
CENTRE FOR DNA FINGERPRINTING AND DIAGNOSTICS, HYDERABAD
Impact
factor
Leptospirosis: An epidemiologic, genomic and evolutionary Lancet Infectious Diseases MICdb - Database of Prokaryotic Microsatellites.
Sreenu, V.B., Ranjitkumar, G., Swaminathan, S., Priya, S., Published in online Bose, B., Narendra Pavan, M., Nagaraju, J., Nagarajaram, database issue.
Predictregulon: A webserver for the prediction of the Nucleic Acids Research32: regulatory protein binding sites and operons in prokaryote W318-320.
Yellaboina S., Seshadri J., Senthil Kumar M. and Ranjan A.
Beta-D-glucoside suppresses TNF-induced activation of Journal of Biological nuclear transcription factor kappaB but potentiates apoptosis. Chemistry 279(32), Sarkar, A., Sreenivasan, Y., Ramesh, G. T., and Manna, S. 33768-33781 May 25 Array-based comparaative genomic hybridization identifies Neoplasia 00:000-000 localized DNA ampilfications and homozygous deletions in (In press).
pancreatic cancer. Bashyam, M.D, Ryan Bair, Young H Kim,Pei Wang, Tina Hernandez-Boussard, Trobert Tibshirani,Anirban Maitra, Jonathan R. Pollack.
Mycobacterium tuberculosis GroEL homologues unusually J. Mol. Biol. (2004) exist as lower oligomers and retain the ability to suppress v.342, 605-617.
R. Qamra, V. Srinivas and S. C. Mande (2004) A conserved Zinc binding site in the largest subunit of DNA- J. Mol. Biol., 342(4): dependent RNA polymerase modulates intrinsic transcription 1143-54.
termination and antitermination but does not stabilize theelongation complex.
King, R.A., Markov, D., Sen, R., Severinov, K. and Weisberg, AmpliBASE MTTM: A Mycobacterium tuberculosis Bioinformatics Published Majeed, A.A., Ahmed, N., Rao, K.R., Ghousunnissa, S., (In press).
Kausar, F., Bose, B., Nagarajaram, H.A., Katoch, V.M.,Cousins, D.V., Sechi, L.A., Gilman, R.H. and Hasnain, S.E.
(2004) AmpliBASE MTTM: A Mycobacterium tuberculosis Bioinformatics Published Majeed, A.A., Ahmed, N., Rao, K.R., Ghousunnissa, S., (In press).
Kausar, F., Bose, B., Nagarajaram, H.A., Katoch, V.M.,Cousins, D.V., Sechi, L.A., Gilman, R.H. and Hasnain, S.E.
(2004) Annexures
Impact
factor
Survey and analysis of microsatellites in the silkworm, Bombyx mori: Frequency, Distribution, Mutations, Markerpotential and their Conservation in heterologous species M. Dharma Prasad, M. Muthulakshmi, M. Madhu, Sunil 1,2,4-thiadiazolidine derivative inhibits Nuclear Transcription Factor-kappaB and its dependent genes Manna, P., Narang, K. K., and Manna, S. K. (2004) Crystal structure of the 65kDa heat shock protein, Chaperonin 60.2 of Mycobacterium tuberculosis.
Molecular genotyping of Helicobacter pylori isolates from different human populations using genomic fingerprinting of ERIC regions: Implications in strain identification andgeographic evolution.
Abid Hussain M, Kauser F, Khan A A, Tiwari S, Habibullah J. Clin. Microbiol. (In press).
Molecular genotyping of a large, multi-centric collection of tubercle bacilli indicates geographical partitioning of strain variation: Implications in global epidemiology of M.
Ahmed N, Alam M, Rajender Rao K, Kauser F, Ashok Kumar N, Qazi N N, Sangal V, Sharma VD, Das R, KatochVM, Murthy KJR, Suneetha S, Sharma S K, Sechi LA,Gilman RH and Hasnain SE (2004).
The cag pathogenicity island (cag-PAI) of Helicobacter pylori is disrupted in majority of patient isolates from Kauser F, Khan AA, Hussain MA, Carroll IM, Ahmad N, Tiwari S, Shouche Y, Das B, Jyohtirmayee CS, Alam M, Ali SM, Habibullah CM, Sierra R, Megraud F, Sechi LAand Ahmed N (2004).
Formation of an oxo-radical of peroxovanadate during reduction of diperoxovanadate with vanadyl sulfate or T. Ramasarma and H. N. Ravishankar (2004) Design, Synthesis, and Evaluation of Mixed Imine-Amine Pyrrolobenzodiazepine Dimers with Efficient DNA-Binding Affinity and Potent Cytotoxicity.
Ahmed Kamal, G. Ramesh, O. Srinivas, P. Ramulu, N.
Laxman ,Tasneem Rehana, M.Deepak, M.S. Achary andH. A. Nagarajaram (2004).
Activation of activator protein-1 DNA binding activity due to low level of manganese exposure in pheochromocytoma DBT Annual Report 2004 - 2005
Impact
factor
Wise K., Manna S., Barr J., Gunasekar P., and Ramesh G.
Microevolution between paired antral and paired antral and Journal of Human Genetics, corpus Helicobacter pylori isolates recovered from individual 49:408-413.
Carroll I M, Ahmed N, Beesley S M, Khan A A, Ghousunnissa Altered Cytoki ne Expression in Tissues of Mice Subjected Mole cular and Cellular Felix, K., Wise, K., Manna, S., Yamauchi, K., Wilson, B. L., T homas, R., Kulkarni, A., Pellis, N. R., and Ramesh, G. T.
(2004): Molecular genetic analyses of b-thalassemia in South India Journal of Human Genetics, reveals rare mutations in the b-globin gene.
Murali Dharan Bashyam, Leena Bashyam, Gorinabele R Savithri, Munimanda Gopikrishna, Vartul Sangal, AkelaRadha Rama Devi. (2004) Molecular phylogeny of the nasuta subgroup of Drosophila Genes and Genetic systems based on 12S rRNA, 16S rRNA and CoI mitochondrial genes, 79: 293-299.
RAPD and ISSR polymorphismsNagaraja, J. Nagaraju andH. A. Ranganath (2004) Spider silks: A possible key to evolution of spidersNagaraju. Heredity 93: 520-521.
Pat translocation and XX sex reversal in a phenotypic boy Genetic Counseling with cryptorchidism and delayed development.
Prabhakara K, Angelena M, Ramadevi AR (2004) Familial Premature centromere division versus C-anaphases in American Journal of Medical cultures: Need for consensus and guidelines.
Recurrent proximal 18p monosomy and 18q trisomy in a Ann Genet (Accepted).
family with a maternal pericentric inversion of chromosome18.
Prabhakara K, Wyandt HE, Huang XL, Prasad KS, Ramadevi Phylogenetic relationships of three new microsporidian Journal of Invertebrate isolates from the silkworm, Bombyx mori.
S. N. Rao, M. Muthulakshmi, S. Kanginakudru, and J.
PCR based analysis of the cag-PAI of Helicobacter pylori Gasteroenterol. Hepatol. from saliva: An approach for rapid molecular genotyping in (In press) Tiwari SK, Khan AA, Khan SA, Ali SM, Habeeb A, Kauser F, Hussain MA, Ahmed N and Habibullah CM. (2004).
Annexures
Impact
factor
Genetic analysis of Casuarinas using ISSR and FISSR Yashodha R, Kathirvel M, Sumathi R, Gurumurthi K, Mycobacterium tuberculosis isolate with a distinct genomic identity overexpresses a TAP like efflux pump.
Siddiqi N, Das R, Pathak N, Banerjee S, Ahmed N, Katoch Genomics of Mycobacterium tuberculosis:Old threats and Synthesis, anti-fungal, antitumor and anti-inflammatory activities of some new 5-substitutedarylimino-2-N-p- tolylsulphonyl-3-oxo-1,2,4-thiadiazolidines.
Manna, P, Singh, R., Narang, K. K., and Manna, S. K.
Prediction of DtxR regulon: Identification of binding sites and operons controlled by Diphtheria toxin repressor inCorynebacterium diphtheriae.
Yellaboina S., Ranjan S., Chakhaiyar P., Hasnain SE, and Comparative proteomics of the M. leprae binding protein Infection Genet Evol 4: 21-28.
myelin P0: its implication in leprosy and otherneurodegenerative diseases.
Vardhini D, Suneetha S, Joshi DSM, Karuna S, Magee X, Vijayalakshmi DSR, Sridhar V, Karunakar KV, Ahmed N,Archelos JJ, Suneetha LM (2004).
Genetic characterization of the Indian cattle breeds, Ongole and Deoni (Bos indicus), using microsatellite markers - a Metta M, Kanginakudru S, Gudiseva N, Nagaraju J. (2004) Genetic diversity and relationships in mulberry (genus Morus) as revealed by RAPD and ISSR marker assays.
Awasthi AK, Nagaraja G, Naik G, Kanginakudru S, Revisiting the pestilence of Helicobacter pylori: insights Infection Genet Evol. (In press).
into geographical genomics and pathogen evolution.
Carroll I M, Khan AA and Ahmed N (2004).
NBSdb: New Born Screening Database (2004) Buddhaditta Bose, Gyan Rajkumar, M. Narendar Pavan, The extracytoplasmic function sigma factors: role in DBT Annual Report 2004 - 2005
NATIONAL BRAIN RESEARCH CENTRE, MANESAR
Impact
factor
Altered proteasomal function due to the expression of Nature Medicine 10, 148-154, polyglutamine-expanded N-terminal huntingtin induces 2004*apoptosis by caspase activation through mitochondrialcytochrome c release.
Search efficiency but not response interference affects visual Neuron 30, 583-591(2001) .
Polyglutamine length-dependent interaction of Hsp40 and Human Molecular Genetics, Hsp70 family chaperones with truncated N-terminal 10, 1049-1059, 2001*huntingtin: Their role in suppression of aggregation andcellular toxicity.
Bilateral effects of spinal overhemisections on the Human Molecular Genetics, development of the somatosensory system in rats.
Functional analysis of the rod photoreceptor cGMP Hum. Mol. Genetics phosphodiesterase alpha -subunit gene promoter: Nrl and 12(4) : 365-73, (2003)Crx are required for full transcriptional activity Growth-associated protein-43 is required for commissural J Neurosci. 22(1), 239-47 axon guidance in the developing vertebrate nervous system. (2002) . * Thioltransferase (glutaredoxin) mediates recovery of motor J Neurosci. 2002 Oct 1;22(19): neurons from excitotoxic mitochondrial injury.
Estrogen and neuroprotection: higher constitutive FASEB J. 2004 Jul; expression of glutaredoxin in female mice offers protection 18(10):1102-4.
against MPTP-mediated neurodegeneration.
Glutaredoxin is essential for maintenance of brain FASEB J. 2003 Apr;17(6): mitochondrial complex I: studies with MPTP.
A frameshift mutation and alternate splicing in human brain J Biol Chem. 2004 generate a functional form of the pseudogene cytochrome Jun 25;279(26):27383-9 P4502D7 that demethylates codeine to morphine.
Barrier-to-autointegration factor (Baf) interacts with the J Biol Chem. 279(19): cone-rod homeobox (Crx) and represses its transactivation 19800-7 . * Increased expression of p62 in expanded polyglutamine- Journal of Biological Chemistry expressing cells and its association with polyglutamine , 279, 11690-11695, 2004. Neurocomputational model and algorithm for phase J Biol Chem. 2002 Sep 4 Differential metabolism of alprazolam by liver and brain Pharmacogenomics J. 2002; cytochrome (P4503A) to pharmacologically active 2(4):243-58 Constitutive expression and localization of the major drug Mol Brain Res. 2002 metabolizing enzyme, cytochrome P4502D in human brain Jun 30;103(1-2):49-61 Detection and localization of protein-acetaldehyde adducts Alcohol Clin Exp Res. 2002 in rat brain after chronic ethanol treatment.
Toxicological consequences of differential regulation of Arch Biochem Biophys. 2002 cytochrome p450 isoforms in rat brain regions by Mar 1;399(1):56-65. Annexures
Impact
Factor
Mitochondrial dysfunction in excitotoxicity mediated by L- Neurochem Int. 2002 May; Protein thiol oxidation by haloperidol results in inhibition Neurochem Int. 2001 of mitochondrial complex I in brain regions: comparison with Apr;38(5):425-35 Human brain thioltransferase: constitutive expression and Mol Brain Res. 2000 localization by fluorescence in situ hybridization.
Reversal of MPTP induced complex I inhibition in brain Neurosci. Lett. 289: regions by disulfide reductant, dithiothreitol Multiple forms of cytochrome P450 and associated Biochem Pharmacol. 2000 monooxygenase activities in human brain mitochondria.
Cytochrome P4502E (CYP2E) in brain: constitutive Arch Biochem Biophys. expression, induction by ethanol and localization by 2000 Jan 1;373(1):23-34 Dexamethasone induces total P450 levels but not P4503A Neurochemistry International Estrogen receptor antagonist down regulates glutaredoxin J. NeuroChem and renders female mice susceptible to excitatory amino acid (In Press) Constitutive expression and localization of cytochrome Mol. Brain Res. p4501a1 in rat and human brain: presence of splice variant (In Press). Dynamic dissociation of visual selection from saccade J. Neurophysiology IETE Journal of Research:2003. Institution of Electronicsand TelecommunicationEngineers 49 (2): 135-143, 2003 Parallel programming of double step saccade sequences: Vision Research44: Failure to express GAP- 43 during neurogenesis affects cell Mol. Cell Neurosci. 2001 cycle regulation and differentiation of neural precursors and Jan; 17(1) : 54-66 . * Targeted disruption of GAP-43 in P19 embryonal carcinoma Brain Res. 853 : 384-395.
cells inhibits neuronal differentiation as well as acquisition (2000). . * Failure to express GAP-43 leads to disruption of a Mol Cell Neurosci. 2004 multipotent precursor and inhibits astrocyte differentiation A control theoretic analysis of neuronal information IEEE Transactions on processing: A study from electrophysiological data Evolutionary Computing 5(3):292-305, 2002*.
Cognitive processing and activation: An analysis using Lecture Notes on Artificial Stochastic Transition and Stochastic Resonance Intelligence 2275, 98-110,2002*.
Stochastic Resonance Imaging and Therapy: Preliminary Journal of Institution of Findings on Considering the Brain as a Stochastic Processor Electronics and Tele- communication Engineers,49(2), 1-12, 2003.
DBT Annual Report 2004 - 2005
Impact
Factor
Stochastic Resonance as an Emerging Technique for Lecture Notes on Computer Neuromodulation : Using Nonlinear Dynamics to Analyze Science, 2004 [in press].
EEG and pharmacologically-induced Language Transition Pro-apoptotic protein kinase C??in associated with Journal of Quantitative intranuclear inclusions in a transgenic model of Huntington’s Linguistics, 11, 2004 [in press].
Recent advances in understanding the pathogenesis of J. Neurochem: 87, 395-406. polyglutamine diseases: involvement of molecular 2003* chaperones and ubiquitin-proteasome pathway Inhibition of proteasomal function by curcumin induces J. Chem. Neuroanat 26: Trehalose alleviates polyglutamine-mediated pathology in J. Neurochem: In Press (2004)* transgenic mouse model of Huntington’s disease.
Patterned activity via dorsal quadrant inputs is necessary J. Comparative Neurology.
for the formation of organized somatosensory maps NATIONAL CENTRE FOR PLANT GENOME RESEARCH, NEW DELHI
Light mediated regulation defines a minimal promoter region of TOP2. Hettiarachchi, G. H. C. M., Yadav, V., Reddy, M. K., Chattopadhyay, S and Sopory S. K., (2003).
Long term transcript accumulation during the development of dehydration adaptation in Cicer arietinum L.Boominathan P., Rakesh Shukla , Arun Kumar , Dipak Manna , Divya Negi,Praveen K. Verma , Debasis Chattopadhyay (2004).
Terpenoid indole alkaloid biosynthetic pathway gene expression corresponds to accumulation of related alkaloids in Catharanthus roseus (L.) Dutta A, Batra J, Pandey-Rai S,Singh D, Kumar S and Sen J. 2004.
Isolation and characterization of sequence-tagged microsatellite sites markers in chickpea (Cicer arietinum L.).
Salt tolerant mutants in GLYCOPHYTIC SALINITY RESPONSE (GSR) genes in Catharanthus roseous. Panday Rai S, Luthra R and Kumar S (2003) Growth and terpenoid indole alkaloid production in Catharanthus roseus hairy root clones in relation to left-and right-termini-linked Ri T-DNA gene integration.
Batra J, Dutta A, Singh D, Kumar S, Sen J. 2004.
Use of a herbicide or lysine and threonine for non-antibiotic selection of transgenic chickpea. Tewrai-Singh N, Sen J, Kiesecker H, Reddy VS, Jacobsen HJ andGuha-Mukherjee (2004) Regulation of unipinnate character in the distal tendrilled domain of compound leaf-blade by the gene MULTIFOLIATE PINNA (MFP) in pea Kumar S, Rai SK,Pandey-Rai S, Srivastava S, Singh D (2004) High yields of artemisinin by multiharvest of Artemisia annua crops. Kumar S, Gupta SK, Singh P, Bajpai P, Gupta MM, Singh D, Gupta AK and Sharma S (2004) Annexures

Source: http://www.dbtindia.gov.in/annualreports/2004-05/Extras/annex-07.pdf