Doctor and patient: using symptom checklists to sell drugs -

JANUARY 26, 2012, 12:18 PM
Have These Symptoms? Buy This Drug
Are symptom checklists more for marketing than for diagnosis?It began suddenly a little over 10 years ago. With impressive fluency, friends, family members and patients startedasking me about random medications, the odd syncopations of those invented, polysyllabic pharmaceutical brandnames – Viagra, Lipitor — rolling perfectly off their tongues.
The questions they asked about those drugs did not reflect breaking news or the results of scientific studies. Rather,they were a reflection of sound bites, advertisements and the draw of celebrities who endorsed them, all part of carefullyconceived marketing schemes.
There’s no question that Americans like their prescription medications. We spend nearly twice as much per person onpharmaceuticals as patients in other developed countries do, and we account for nearly half of all sales worldwide. Butin 1997, when the Food and Drug Administration loosened its regulations and the United States became one of only fourcountries to allow direct-to-consumer advertising (the others are New Zealand, Bangladesh and South Korea), weentered a new era in pharmaceutical consumerism.
Players in the drug industry began aiming their advertisements at patients, and their goal was to define in the minds ofpatients not only the beneficial effects of the drugs but also the diseases they were designed to treat.
As Vince Parry, a well-known marketing expert, counseled his colleagues, “If you can define a particular condition andits associated symptoms in the minds of physicians and patients, you can also predicate the best treatment for thatcondition.” The phenomenon is sometimes referred to as “disease mongering,” redefining what is normal and abnormal in a waythat widens potential markets for those who sell treatments. And, as detailed in a recent study in the journal SocialScience & Medicine, one marketing strategy has accomplished more in this regard than any other by using what hascome to be the very symbol of quality and reliability for doctors and patients everywhere: the checklist.
Placed on Web sites, on downloadable apps and in pamphlets in doctors’ offices, these checklists of symptoms havebecome a critical part of every major pharmaceutical marketing campaign. What makes them so attractive is that theymake it easy for patients to diagnose their own ailments, to take some control over their own health.
What makes the checklists so powerful is their ability to influence patient preferences.
The makers of Yaz, a birth control pill, for example, used a checklist to help promote the use of their drug as a treatmentfor premenstrual dysphoric disorder, a controversial diagnosis said to affect up to 10 percent of women. Alongside linksto articles on fashion, makeup, hair and celebrity news, Yaz’s Web site offered a “Body Diary” checklist to help patientsdetermine whether they suffer from the disorder.
Taking its cues from the Diagnostic and Statistical Manual of Mental Disorders, or D.S.M., which mental healthprofessionals use to diagnose disease, the checklist offered watered-down and potentially more inclusive descriptions. Asymptom described in the D.S.M. as “persistent and marked anger or irritability or increased interpersonal conflicts”appeared in the Yaz questionnaire as “Felt angry, or irritable.” “Marked change in appetite, overeating, or specific foodcravings” became “Had increased appetite or overate; or had cravings for specific foods.” The printable results thatpatients could then take to their doctors (the site has since been taken down) were on a form emblazoned with the birthcontrol brand.
“The whole point of tools like this one is to confine people’s experiences into these categories in order to make a diagnosis in line with the branded drug,” said the author of the study, Mary Ebeling, an assistant professor of sociologyat Drexel University in Philadelphia who got interested in the use of checklists while doing research at a marketing firm.
“I became really intrigued when I saw a group of marketers sitting around a table in Midtown Manhattan and comingup with symptoms.” Some symptom checklists are clearly branded, so patients and clinicians can easily discern the pharmaceutical interestsinvolved. But many are less obvious or are used as part of advocacy groups’ materials or awareness events. For example,National Depression Screening Day, held annually at college campuses, military sites and community centers across thecountry, uses a symptom checklist called the Patient Health Questionnaire, or PHQ-9. The nine questions are based ona well-known anxiety screening tool, but its copyright is held by Pfizer, maker of the antidepressant Zoloft.
It’s difficult to ascertain whether efforts aimed directly at consumers ultimately translate into real sales. A recentmarketing study found that fewer than 3 percent of patients mentioned a marketed drug by name and less than 1percent asked for a prescription. However, a separate study comparing patients in Canada, where direct-to-consumermarketing is illegal, with those in the United States found that American patients were more than twice as likely torequest advertised medications.
But sales may not be the only measure of success for these campaigns. “The whole point of this marketing and brandingis that the name ends up in the minds of the consumers,” Dr. Ebeling said.
While the Obama administration is looking to force pharmaceutical companies to disclose any payments to doctors thatmight influence their treatment decision, marketing efforts directed at patients are likely to continue to grow. And withthose efforts comes a widening, not shrinking, circle of interests that can influence their care.
“There are pharmaceutical marketers, medical device makers, health insurers and whoever is involved in the healthindustry sitting in the exam room, not just the doctor and patient,” Dr. Ebeling said.
She added, “I find that disturbing, because it’s our health and the quality of our lives that are at stake.” Correction: An earlier version of this article incorrectly listed Pakistan as one of four countries that allow direct-to-consumer advertising of pharmaceuticals. The four countries are the United States, New Zealand, South Korea andBangladesh, not Pakistan. Copyright 2012 The New York Times Company 620 Eighth Avenue New York, NY 10018


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