Material Safety Data Sheet Acyclovir MSDS Section 1: Chemical Product and Company Identification Product Name: Acyclovir Contact Information: Catalog Codes: SLA4732 Sciencelab.com, Inc. 14025 Smith Rd. CAS#: 59277-89-3 RTECS: UP0791400
US Sales: 1-800-901-7247 International Sales: 1-281-441-4400 TSCA: TSCA 8(b) inventory: No products were found. CI#: Not available. CHEMTREC (24HR Emergency Telephone), call: Synonym: Zovirax, Aciclovir; 9-[(2-
International CHEMTREC, call: 1-703-527-3887 Chemical Name: 6H-Purin-6-one, 1,9-dihydro-2-amino-9- ((2-hydroxyethoxy)methyl)- For non-emergency assistance, call: 1-281-441-4400 Chemical Formula: C8-H11-N5-O3 Section 2: Composition and Information on Ingredients Composition: % by Weight Toxicological Data on Ingredients: Acyclovir: ORAL (LD50): Acute: >20000 mg/kg [Rat]. >10000 mg/kg [Mouse]. Section 3: Hazards Identification Potential Acute Health Effects: Hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. Potential Chronic Health Effects: CARCINOGENIC EFFECTS: 3 (Not classifiable for human.) by IARC. MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. TERATOGENIC EFFECTS: Not available. DEVELOPMENTAL TOXICITY: Not available. Repeated or prolonged exposure is not known to aggravate medical condition. Section 4: First Aid Measures Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Cold water may be used. WARM water MUST be used. Get medical attention. Skin Contact: In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention. Serious Skin Contact: Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek medical attention. Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention. Serious Inhalation: Not available. Ingestion: Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms appear. Serious Ingestion: Not available. Section 5: Fire and Explosion Data Flammability of the Product: May be combustible at high temperature. Auto-Ignition Temperature: Not available. Flash Points: Not available. Flammable Limits: Not available. Products of Combustion: These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2.). Fire Hazards in Presence of Various Substances: Slightly flammable to flammable in presence of heat. Non-flammable in presence of shocks. Explosion Hazards in Presence of Various Substances: Risks of explosion of the product in presence of mechanical impact: Not available. Slightly explosive in presence of open flames and sparks. Fire Fighting Media and Instructions: SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. Do not use water jet. Special Remarks on Fire Hazards: Not available. Special Remarks on Explosion Hazards: Fine dust dispersed in air in sufficient concentrations, and in the presences of an ignition source is a potential dust explosion hazard. Section 6: Accidental Release Measures Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements. Large Spill: Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system. Section 7: Handling and Storage Precautions:
Keep locked up. Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporatethe residue under a fume hood. Ground all equipment containing material. Do not ingest. Do not breathe dust. Wear suitableprotective clothing. In case of insufficient ventilation, wear suitable respiratory equipment. If ingested, seek medical adviceimmediately and show the container or the label. Avoid contact with skin and eyes. Storage: Keep container tightly closed. Keep container in a cool, well-ventilated area. Section 8: Exposure Controls/Personal Protection Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. Personal Protection: Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves. Personal Protection in Case of a Large Spill: Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product. Exposure Limits: Not available. Section 9: Physical and Chemical Properties Physical state and appearance: Solid. (crystalline powder.) Odor: Not available. Taste: Not available. Molecular Weight: 225.2 g/mole Color: White. Off-white. pH (1% soln/water): Not available. Boiling Point: Not available. Melting Point: 257°C (494.6°F) Critical Temperature: Not available. Specific Gravity: Not available. Vapor Pressure: Not applicable. Vapor Density: Not available. Volatility: Not available. Odor Threshold: Not available. Water/Oil Dist. Coeff.: Not available. Ionicity (in Water): Not available. Dispersion Properties: Not available. Solubility: Very slightly soluble in cold water, methanol. Solubility in Water: 1.3mg/ml Solubility in Methanol: 0.2mg/ml Section 10: Stability and Reactivity Data Stability: The product is stable. Instability Temperature: Not available. Conditions of Instability: Excess heat, excess dust generation. Incompatibility with various substances: Not available. Corrosivity: Not available. Special Remarks on Reactivity: Not available. Special Remarks on Corrosivity: Not available. Polymerization: Will not occur. Section 11: Toxicological Information Routes of Entry: Inhalation. Ingestion. Toxicity to Animals: Acute oral toxicity (LD50): >10000 mg/kg [Mouse]. Chronic Effects on Humans: CARCINOGENIC EFFECTS: 3 (Not classifiable for human.) by IARC. MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. Other Toxic Effects on Humans: Hazardous in case of skin contact (irritant), of ingestion, of inhalation. Special Remarks on Toxicity to Animals: Not available. Special Remarks on Chronic Effects on Humans: May cause adverse reproductive effects and birth defects (teratogenic) Special Remarks on other Toxic Effects on Humans: Acute Potential Health Effects: Skin: May cause skin irritation. Eyes: May cause eye irritation. Inhalation: May cause respiratory tract irritation. Ingestion: May cause gastrointestinal tract irritation with abdominal pain, nausea, vomiting, diarrhea or decreased motility or constipation. May affect behavior/central nervous system(hallucinations, convulsions, muscle contraction or spasticity, somnolence, dizziness, vertigo, headache, lethargy, tremors, confusion, seizures, delirium, jitters, lightheadedness, obtundation, fatigue, insomnia, irritability, mental depression, antipsychotic, coma), brain, respiratory system (sputum), blood (agranulocytosis, thrombocytopenia, leukopenia, thromocytosis, lymphopenia), urinary system (kidney failure, acute tubular necrosis). Other symptoms may include sore throat, thirst, muscle cramps, perspiration, fever, lymphadenopathy, substernal burning sensation, leg pain, hematuria, hypotension, heart palpitation, bone marrow hypoplasia. May cause allergic dermatits with urticaria or rash, acne Chronic Potential Health Effects: Ingestion: Prolonged or repeated ingestion may affect the urinary system, and metabolism (anorexia). Section 12: Ecological Information Ecotoxicity: Not available. BOD5 and COD: Not available. Products of Biodegradation: Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise. Toxicity of the Products of Biodegradation: The product itself and its products of degradation are not toxic. Special Remarks on the Products of Biodegradation: Not available. Section 13: Disposal Considerations Waste Disposal: Waste must be disposed of in accordance with federal, state and local environmental control regulations. Section 14: Transport Information DOT Classification: Not a DOT controlled material (United States). Identification: Not applicable. Special Provisions for Transport: Not applicable. Section 15: Other Regulatory Information Federal and State Regulations: No products were found. Other Regulations: EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances. Other Classifications: WHMIS (Canada): Not controlled under WHMIS (Canada). DSCL (EEC): R36/38- Irritating to eyes and skin. R40- Possible risks of irreversible effects. S2- Keep out of the reach of children. S36/37- Wear suitable protective clothing and gloves. S46- If swallowed, seek medical advice immediately and show this container or label. HMIS (U.S.A.): Health Hazard: 2 Fire Hazard: 1 Reactivity: 0 Personal Protection: E National Fire Protection Association (U.S.A.): Health: 2 Flammability: 1 Reactivity: 0 Specific hazard: Protective Equipment: Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Splash goggles. Section 16: Other Information References: Not available. Other Special Considerations: Not available. Created: 10/09/2005 03:37 PM Last Updated: 11/01/2010 12:00 PM The information above is believed to be accurate and represents the best information currently available to us. However, wemake no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assumeno liability resulting from its use. Users should make their own investigations to determine the suitability of the information fortheir particular purposes. In no event shall ScienceLab.com be liable for any claims, losses, or damages of any third party or forlost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if ScienceLab.comhas been advised of the possibility of such damages.
Dust Mite Lure Although there are many methods of house dust mite control, they are not without their limitations. Synthetic chemical acaricides found in commercially available products, can be used to control house dust mites by applying them to house dust mite habitats (carpets, mattresses, soft furnishings). Permethrin can be impregnated on to mattress-liners, and a clinical trial de
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