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Personal Details
married with Dr. Sibylle Greiner, 3 children Education
06/1984 Final Examination (Abitur), Goethe-Gymnasium, Neu-Isenburg Medical state exam, Georg-August-Universität Göttingen Doctoral Thesis
07/1994 “Neuroplastic reorganisation of somatosensory afferences in the cortex of the neonatal enucleated rat” Prof. Dr. med. Dr. h.c. mult. J.R. Wolff (Klinische Anatomie und Neurosurgical Experiences
Department of Neurosurgery, University of Münster (Head: Univ.-Prof. Dr. med. H. Wassmann) Department of Neurosurgery, Central Military Hospital Koblenz (Head: FLA Dr. med. P. Klawki) Department of Neurosurgery, University of Münster Experimental works on brain slices, Institut of Neurophysiology, University of Münster (Head: Univ.-Prof. Dr. med. E.-J. Speckmann) Department of Neurosurgery, University of Münster 24.04.1999
Examination
Neurosurgery
Attending neurosurgeon at the Department of Neurosurgery, University of Münster Department of Neurosurgery, Graduate School of Medicine, University of Kyoto, Japan (Dir.: Professor N. Hashimoto MD, PhD) 20.04.2004
Privatdozent (comparable with PhD), Subject: Bioelectrical changes in isolated human brain slices after induction of mild and moderate hypothermia. Head of the Department of Neurosurgery and Spine Surgery, Niels-Stensen-Kliniken, Marienhospital Osnabrück. Medical Vice-Director, Marienhospital Osnabrück Acknowledgement as “LEVEL 1 Trauma Centre” Clinical Specialisation
Clinical Studies
Participation as „Clinical Investigator“,Phase III- Participation as „Clinical Investigator“ Multicenterstudy: IHAST II (Mild Intraoperative Hypothermia during Surgery for Participation as “Clinical Investigator”, Phase III- Mulicenterstudy: SyNAPSE, (Progesterone and sTBI) PUBLISHED MANUSCRIPTS IN REFEREED JOURNALS
GREINER C.
Decompressive craniectomy in traumatic brain injury and malignant brain infarction.
AINS 2008; 43:682-690.
GREINER C.
Decompressive craniectomy in traumatic brain injury and malignant brain infarction.
AINS 2008; Quiz 691.
GREINER C, WASSMANN H., PALKOVIC S., GAUSS C.
Revascularization procedures in internal carotid artery pseudo-occlusion.
Acta Neurochir. 2004; 146:237-243.

GREINER C, RICKERT CH, MÖLLMANN FT, RIEGER B, SEMIK M, HEINDEL W,
WASSMANN H.
Plasma cell granuloma involving the brain and the lung.
Acta Neurochir. 2003; 145:1127-1131.

GREINER C, HÜLSMANN S,WASSMANN H, MOSKOPP D, SCHMIDINGER A, WÖLFER J,
KÖHLING R, LÜCKE A, SPECKMANN EJ.
Neuroprotection of mild hypothermia: differential effects.
Brain Res. 1998; 786:267-269.
GREINER C, RÖHL JE, GORGJI A, WASSMANN H, SPECKMANN EJ.
Different actions of γ-hydroxybutyrate – a critical outlook.
Neurol. Res. 2003; 25:759-763.
GREINER C, SCHMIDINGER A, HÜLSMANN S, MOSKOPP D, WÖLFER J, KÖHLING R,
SPECKMANN EJ, WASSMANN H.
Acute protective effect of nimodipine and dimethyl sulfoxide against hypoxic and ischemic
damage in brain slices.
Brain Res. 2000; 887:316-322.

GREINER C, WÖLFER J, HÜLSMANN S, VANHATALO S, KÖHLING R, PANNEK HW,
SPECKMANN EJ, WASSMANN H.
Bioelectrical behaviour of hypoxic human neocortical tissue under the influence of nimodipine
and dimethyl sulfoxide
Brain Res. 2003; 959:199-205.

GREINER C, WÖLFER J, WASSMANN H, KÖHLING R, SPECKMANN EJ.
Effects of methohexital on bioelectrical reactions in guinea pig hippocampal slices during
hypoxia.
Neurosci. Lett. 2002; 329:227-231
GRIMMELT AC, EITZEN S, BALAKHADZE I, FISCHER B, WÖLFER J, SCHIFFBAUER H,
GORJI A, GREINER C.
Closed traumatic brain injury model in sheep mimicking high-velocity, closed head trauma in
humans
Cen Eur Neurosurg. 2011; 72(3):120-126

FISCHER BR, SPECKMANN EJ, GREINER C, GORJI A, WÖLFER J, WASSMANN H.
Hyperbaric oxygen in neurosurgery.
Acta Neurochir. 2009; 151:415-8; Epub ahead of print

HASSELBLATT M, JUNDT G, GREINER C, RAMA B, SCMMÄL F, IGLESIAS-ROZAS JR,
VAN DEN NEES JA, PAULUS W
Psammomatoid ossifying fibroma on the neurocranium
J. Neurosurg. 2005; 102:1152-1154

HÜLSMANN S, KÖHLING R, GREINER C, MOSKOPP D, LÜCKE A, WASSMANN,
SPECKMANN EJ:
Neuroprotection by 21-aminosteroids: insights from latencies of anoxic terminal negativity in
hippocampus slices of guinea pig.
Neurol. Res. 1999; 21: 305-308.
HÜLSMANN S, GREINER C, KÖHLING R, WÖLFER J, MOSKOPP D, RIEMANN B, LÜCKE
A, WASSMANN, SPECKMANN E-J
Dimethyl sulfoxide increases latency of anoxic terminal negativity in hippocampal slices of
guinea pig in vitro
Neurosci. Lett. 1999; 261:1-4.

KÖHLING R, GREINER C, WÖLFER J, WASSMANN H, SPECKMANN EJ.
Optical monitoring of pO2 changes and simultaneous recording of bioelectric activity in
human and animal brain slices.
J. Neurosci. Methods 1998; 85:181-186.

KÖHLING R, SCHMIDINGER A, HÜLSMANN S, VANHATALO S, LÜCKE A, STRAUB H,
SPECKMANN EJ, TUXHORN I, WOLF P, LAHL R, PANNEK H, OPPEL F, GREINER C,
MOSKOPP D, WASSMANN H.
Anoxic terminal negative DC-shift in human neocortical slices in vitro
Brain Res. 1996; 741:174-179.
KURRE W, GREINER C, NIEDERSTADT T.
Der besondere Fall: Spinales Subduralhämatom.
Radiologie up2date. 2003; 3:181-183.

LINK TM, GREINER C, PETERS PE.
Mediastinalverbreiterung bei Hirntumor.
Radiologe 1992; 32:619-620.
MOELLER M, FREUND M, GREINER C, SCHWINDT W, GAUS C, HEINDEL W.
Real time fMRI – a tool for the routine presurgical localization of the motor cortex.
Eur. J. Radiol. 2005; 15:292-295.

RICKERT CH, GREINER C, RELLENSMANN G, KEHL HG, SCHELD HH, PAULUS W,
FECHNER G.
Mycotic cerebral vasculitis in a paediatric cardiac transplant patient excludes misadventure.
Int. J. Legal Med. 2002; 116:233-237.

SCHMIDINGER A, GREINER C, REINKER S, KÖHLING R, LÜCKE A, STRAUB H,
SPECKMANN EJ, MOSKOPP D, WASSMANN H, LAHL R, PANNEK H, OPPEL F.
Flat and steep terminal negativity in the DC-potential after deprivation of oxygen and glucose
in human neocortical slices.
Brain Res. 1998; 794:28-34
SCHRÖDER J, GREINER C, LILJENQVIST U, WASSMANN H.
Complications of halo treatment for cervical spine injuries in patients with ankylosing
spondylitis – report of three cases.
Arch. Orthop. Trauma Surg. 2003; 123:112-114.
SCHULZE K, GREINER C, BUTTERWEGE M
Acute intracranial hemorrhage during delivery – A Case Report
Z. Geburtsh. Neonatol. 2010, 214: 123-125.

STUBBE HD, GREINER C, VAN AKEN H, WESTPHAL M, RICKERT C, WASSMANN H,
AKCOKUK A, DAUDEL F, ERREN M, HINDER F.
Cerebral vascular and metabolic response to sustained systemic inflammation in ovine
traumatic brain injury.
J. Cereb. Blood Flow Metab. 2004; 24:1400-8.
STUBBE HD, GREINER C, WESTPHAL M, RICKERT C, VAN AKEN H, EICHEL V,
WASSMANN H, DAUDEL F, HINDER F.
Cerebral response to norepinephrine compared to fluid resuscitation in ovine traumatic brain
injury and systemic inflammation.
Crit. Care Med. 2006; 34:2651-7.

TODD MM, HINDMAN BJ, CLARKE WR, TORNER JC for the intraoperative Hypothermia for
Aneurysm Surgery Trial (IHAST) Investigators*.
* […,C. GREINER,.]
N. Engl. J. Med. 2005; 352:135-145.

WASSMANN H, FISCHER B, SPECKMANN EJ, GREINER C, WÖLFER J.
HBO in cerebral hypoxic lesions caused by cerebrovascular obstructions: Experimental and
clinical investigations.
Bulg. Neurosurg. 2004; 9:6-9.

WASSMANN H, GREINER C, HÜLSMANN S, MOSKOPP D.
Zerebroprotektion durch Barbiturate bei zerebrovaskulären Eingriffen in der Neurochirurgie.
Medizin im Dialog 1996; 1:20-23.

WASSMANN H, GREINER C, HÜLSMANN S, MOSKOPP D, SPECKMANN EJ,
MEYER J, VAN AKEN H.
Hypothermia as cerebroprotective measure. Experimental hypoxic exposure of brain slices
and clinical application in critically reduced cerebral perfusion pressure.
Neurol. Res. 1998 20, Suppl 1, S61-S65
WASSMANN H, MOSKOPP D, WOESLER B, LÜCKE A, SPECKMANN EJ, KÖHLING R,
STRAUB H, HÜLSMANN S, GREINER C.
Repetetive hypoxic exposure of brain slices and electrophysiological reponses as an
experimental model for investigation of cerebroprotective measurements.
Neurol. Res. 1996; 18:367-369

WÖLFER J, BANTEL C, KÖHLING R, SPECKMANN E-J, WASSMANN H, GREINER C.
Electrophysiology in ischemic neocortical brain slices: species differences vs. influences of
anaesthesia and preparation.
Eur. J. Neurosci. 2006; 23:1795-800.
.

WÖLFER J, MOSKOPP D, SPECKMANN E-J, WASSMANN H, GREINER C.
Influences of pCO2 and bicarbonate concentration on bioelectric phenomena in ischemic
hippocampal ex-vivo tissue.
Neuroscience 2008; 158:617-622.

Wölfer J, Speckmann EJ, Wassmann H, Gorji A, Greiner C
Remote switching of temperature, gaseous, and aqueous phase in a low-volume interface
chamber for brain slices.
Neurosci Methods 2010; 193 (1):77-81. Epub 2010 Aug 26

Source: http://www.thebrainproject.org/advisoryBoard/Christoph_Greiner/CV.pdf