La tétracycline, connue sous le nom commercial Sumycin, agit en bloquant la fixation de l’ARNt sur la sous-unité 30S ribosomale, interrompant l’élongation de la chaîne protéique bactérienne. Ce mécanisme confère une activité sur un spectre large, incluant bactéries Gram positives, Gram négatives, rickettsies et spirochètes. Sa biodisponibilité digestive varie selon la prise alimentaire et les interactions avec les ions divalents comme calcium et magnésium. Sa diffusion tissulaire est importante, notamment dans les voies respiratoires et génito-urinaires. L’élimination se fait par voie rénale et biliaire. Les effets indésirables incluent photosensibilisation, troubles digestifs et coloration dentaire en cas d’administration précoce. Les guides thérapeutiques mentionnent sumycin prix, en soulignant la nécessité de restreindre son utilisation afin de limiter les résistances acquises.
Formulary_dc
ampicillin, amoxicillin, cloxacillin, dicloxacillin,
ORAL------------------------------------------------------------------
amoxicllin w/ potassium clavulanate, penicillin
multiple generic options (ex. Apri, etc.)
Cephalosporins. . . . . . . . . . . . . . . . . . . . . . . . . . . . . Miscellaneous Antiinfectives. . . . . . . . . . . . . . . . . . . .
cefaclor, cefadroxil, cefdinir, cefradine,
clindamycin, metronidazole, nitrofurantoin
Dapsone, NebuPent, TOBI, Vancocin, Zyvox
Necon 10/11, Ogestrel,Ortho Tri-Cyclen Lo,
DRUGS FOR CANCER Macrolides . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . OTHER CONTRACEPTIVES----------------------------------
azithromycin, clarithromycin, erythromycin ethyl
cyclophosphamide, etoposide, exemestane,
2013 FOCUS Drug Formulary PROGESTIN ONLY------------------------------------------------ and Pharmacy Benefit Guidelines
leucovorin, leuprolide acetate, tretinoin,
Tetracyclines. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
The Scriptsense Focus Drug Formulary defines DRUGS FOR DIABETES
the copayment tier status of the medicines most
INSULINS -------------------------------------------------------- Quinolones . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
commonly prescribed for Scriptsense members. It
may not include all drugs covered by your
Nilandron, Sprycel, Sutent, Tabloid, Tarceva, Temodar, Tasigna, Teslac,
prescription drug benefit. For benefit coverage or restrictions please check your benefit plan Aminoglycosides. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . document(s). This listing is revised from time to Sulfonamides. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . IMMUNOMODULATORS
sulfisoxazole w erythromycin ethylsuccinate
sulfamethoxazole w trimethoprim (SMX-TMP)
Drugs for Tuberculosis. . . . . . . . . . . . . . . . . . . . . . . . .
The coverage tier for each medication has been
indicated. Members pay a Tier 1 copay for most
ORAL ------------------------------------------------------------
generic drugs and selected OTC medicines.
acarbose, glimepiride, glipizide, glipizide XL,
Members pay a Tier 2 copay for higher cost
Revlimid(PA), Simponi(PA), Thalomid(PA),
Drugs for Fungal Infections. . . . . . . . . . . . . . . . . . . . .
generic drugs and formulary (“preferred”) brand
glyburide w/ metformin, glipizide w/ metformin
name drugs. Members pay a Tier 3 copay for non-
HORMONES
formulary and highest cost brand name drugs.
GLUCOCORTICOIDS ---------------------------------------------
dexamethasone, methylprednisolone, prednisolone, prednisone
It is recommended that you have this list of
Drugs For Viral Infections - Influenza & RSV. . . . . .
medications available when you are with your
ANDROGENS---------------------------------------------------
physician and a prescription drug is going to be
part of the treatment for a clinical condition.
Drugs For Viral Infections - Herpes. . . . . . . . . . . . . . . ESTROGENS --------------------------------------------------- Key to Notations: Drugs For Viral Infections - Hepatitis. . . . . . . . . . . . .
Cenestin, Climara, Divigel, Enjuvia, Evamist, Premarin, Vivelle
PA: Prior authorization to ensure clinical
Incivek(PA), Pegasys, Peg-Intron, ribavirin,
appropriateness of this or previous therapy with
DIABETES RELATED DRUGS & SUPPLIES--------------
other similar medications may be needed before
claims for one of these medications will be
Drugs For Viral Infections – HIV/AIDS. . . . . . . . . . . . . ESTROGEN COMBINATIONS------------------------------
ethinyl estradiol & norethindrone acetate
ST: A step therapy protocol is in place for this
esterified estrogens & methyltestosterone
Basic, One Touch II, One Touch Profile, One
medication. If prior medication history does not
Touch Ultra,One, Touch Ultra System, One
ganciclovir, Hivid, Intelence, Invirase,
meet clinical guidelines, authorization may be
Touch UltraMini, One Touch Verio,and Verio
Isentress, Kaletra, lamivudine, lamivudine w/
zidovudine. Lexiva, Prezista, Rescriptor,
PROGESTINS -----------------------------------------------
Accu-Chek Meter, Accu-Chek Miscellaneous.,
QL: Quantity limitations (maximum number of
tablets/capsules, etc. per month or year) are in
MISCELLANEOUS OB/GYN DRUGS-----------------------
Minimed, Surestep Meter, NovoFine Insulin
Drugs for Malaria. . . . . . . . . . . . . . . . . . . . . . . . . .
Bravelle (PA), Follistim(PA), Menopur(PA)
GROWTH HORMONES --------------------------------------- Tier 2 DRUGS FOR INFECTIONS Drugs for Parasites. . . . . . . . . . . . . . . . . . . . . . . . . . ANTIBIOTICS------------------------------------------------- CONTRACEPTIVES THYROID AND ANTITHYROID AGENTS Penicillins . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
This document is in effect January 1, 2013. Formulary consultation and administrative support to provided by:
Engineering Efficient + Effective Drug Therapy ™
THYROID ---------------------------------------------------------
acetazolamide ER, amiloride, bumetanide,
Antileukotrienes. . . . . . . . . . . . . . . . . . . . . . . . . . . . . PSYCHOTHERAPEUTIC AGENTS ----------------------- Antidepressants . . . . . . . . . . . . . . . . . . . . . . . . . . .
amitriptyline, bupropion, SR, XL, citalopram,
DRUGS FOR OSTEOPOROSIS Theophyllines…. . . . . . . . . . . . . . . . . . . . . . . .
doxepin, escitalopram, fluoxetine, imipramine,
ANTILIPEMICS ----------------------------------------------
alendronate sodium (generic for Fosamax)
paroxetine CR, protriptyline, trazodone,
GASTROINTESTINAL ANTIULCER -----------------------------------------------------
Actonel, Actonel-D, Atelvia, Boniva, Evista,
Advicor, Altoprev, Antara, Lescol, Lescol XL,
Livalo, Lovaza, Niaspan, Tricor, TriLipix,
Antipsychotic Agents . . . . . . . . . . . . . . . . . . . . . . . MISCELLANEOUS ENDOCRINE
chlorpromazine, haloperidol, olanzapine,
MISCELLANEOUS CARDIOVASCULAR DRUGS---------
Aciphex, Dexilant, PrevPac, Pylera, Zegerid
ANTICOAGULANTS/ANTITHROMBOTICS-------------
Abilify, clozapine, Latuda, risperidone ODT,
ANTIEMETIC/ANTIVERTIGO ----------------------------- CARDIOVASCULAR DRUGS
dipyridamole, pentoxifylline, ticlopidine,
Fanapt, Fazaclo, Geodon, Invega, Saphris,
CARDIOTONICS ---------------------------------------------- ANXIOLYTICS, SEDATIVES, AND HYPNOTICS---- ANTI-ANGINA ----------------------------------------------
Aggrenox, Arixtra(PA), Brilinta, Effient,
isosorbide dinitrate, isosorbide mononitrate
temazepam, triazolam, zaleplon, zolpidem
DIGESTANTS --------------------------------------------------- DRUGS FOR MISCELLANEOUS BLOOD DISORDERS-- BETA-ADRENERGIC BLOCKERS----------------------
Creon, Pancreaze DR, Ultrase, Ultrase MT,
Ultrase MT12, Ultrase MT18, Ultrase MT20,
CEREBRAL STIMULANTS / ADD-ADHD------------
metoprolol XL, propranolol, propranololLA
OTHER GI PRODUCTS ----------------------------------- CALCIUM CHANNEL BLOCKERS ----------------------- RESPIRATORY / ASTHMA
balsalazide, lactulose, mesalamine rectal
amlodipine, diltiazemCD, diltiazemSR 24,
DRUGS FOR ALLERGY ------------------------------- Oral Antihistamines and Combinations. . . . . . . .
Amitiza(PA), Apriso, Asacol, budesonide EC
Alavert, Claritin, loratadine, cetirizine,
Nuvigil, Provigil (PA) , Ritalin-LA, Strattera,
levocetirizine, montelukast, Zyrtec, Zyrtec-D
ANTIARRHYTHMICS ----------------------------------------
Cimzia(PA), Dipentum, Fosrenol, Lotronex,
DRUGS FOR ALZHEIMER’S DISEASE-----------------------
Metozolv ODT, Pentasa, Relistor, Renagel,
mexiletine, propafenone, quinidine, sotalol
Aricept-23, galantamine, galantamine ER,
NASAL MEDICATIONS ------------------------------------- GENITO-URINARY ACE INHIBITORS ---------------------------------------------
benazepril, captopril, enalapril, fosinopril,
ANTI-INFECTIVES------------------------------------------ MISCELLANEOUS DRUGS FOR CNS----------------------
lisinopril, moexipril, perindopril, quinapril,
Astapro, azelastine nasal spray, Nasonex,
INCONTINENCE AGENTS------------------------------- ANGIOTENSIN II ANTAGONISTS------------------------- DRUGS FOR ASTHMA / COPD -------------------------------
Detrol, Detrol LA, Gelnique, Oxytrol Patch,
Corticosteroids. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ANALGESICS, NARCOTIC--------------------------------------- DIRECT RENIN INHIBITOR---------------------------------- VAGINAL ANTIINFECTIVES -------------------------------
morphine IR, oxycodone IR, fentanyl patch,
clindamycin cream, nystatin, metronidazole,
ANTI-ADRENERGIC BLOCKERS–CENTRAL------ Sympathomimetics. . . . . . . . . . . . . . . . . . . . . . . . COMBINATION ANTIHYPERTENSIVES--------------
AVC Cream, Cleocin Vaginal Tab, Gynazole
Arcapta, Foradil, levalbuterol for inhalation,
DRUGS FOR BPH-------------------------------------------
alfuzosin, doxazosin, tamsulosin, terazosin,
ANALGESICS, NSAIDs ----------------------------------------
diclofenac, diflunisal, etodolac, ibuprofen,
Combination Drugs and Others. . . . . . . . . . . . . . . . . MISCELLANEOUS UROLOGICALS-----------------------
Arthrotec, Celebrex (ST)(QL) Flector Patch,
Caverject, Cialis(ST)(QL), Levitra (QL)(ST),
Diovan HCT, Edarbyclor, Exforge, Exforge
Advair, Atrovent HFA, Combivent, Daliresp,
DIURETICS ------------------------------------------------------ MIGRAINE AGENTS------------------------------------------- CENTRAL NERVOUS SYSTEM
This document is in effect January 1, 2013. Formulary consultation and administrative support to provided by:
Engineering Efficient + Effective Drug Therapy ™
SPECIALTY DRUGS
Relpax (QL), sumatriptan(QL) nasal spray
and injection, Zomig (QL), Zomig ZMT (QL),
Coverage for “Specialty Drugs” varies from ANTI-INFECTIVE AND ANTI-INFLAMMATORY plan to plan. Your prescription benefit may COMBINATIONS ------------------------------------------------ not cover some or all of these items. Please
multiple medicines w/ generics, ofloxacin
check your pharmacy benefit information if ANALGESICS, MISCELLANEOUS ---------------------------- you have questions.
Specialty Drugs are “bioengineered” oral or injectable
Cuprimine, Cymbalta, Nucynta, Nucynta ER
DERMATOLOGICALS
medicines that target and treat complex medical
ACNE -------------------------------------------------------------
conditions including: blood disorders, cancers,
ANTICONVULSANTS ---------------------------------------
infertility, hormone or enzyme deficiencies, multiple
sulfacetamide sodium external suspension
sclerosis, rheumatoid arthritis, and a growing list of
sulfacetamide w sulfur external emulsion
Specialty drugs are complex compounds and some
have unique “handling” requirements. The FDA in
selected situations has required dispensing from a
Carbatrol, Diastat, Felbatol, Gabitril, Sabril
Epiduo, Finacea, Metrogel, Retin-A Micro
single pharmacy or a limited set of “approved”
DRUGS FOR DEPENDENCY -------------------------------
pharmacies. Some “specialty” drugs are oral tablets
ANTIBIOTICS ---------------------------------------------------
or capsules while others require injection. The result
Campral, Chantix(QL), Suboxone, Subutex
erythromycin, clindamycin, metronidazole,
is that many drugs can be distributed directly to
DRUGS FOR PARKINSONS DISEASE ----------------------
patients, while others will be sent to physicians or
Altabax, Bactroban Nasal Ointment, Noritate
home health companies or other professional settings
carbidopa/levodopa, pramipexole, ropinirole,
ANTIVIRALS ----------------------------------------------------
Azilect, carbidopa/entacapone/levodopa,
Most plan sponsors will apply “step edits” or prior
authorization criteria prior to the dispensing or
FUNGICIDES ----------------------------------------------------
administration of a specialty drug. These
requirements ensure appropriate use of a specialty
SKELETAL MUSCLE RELAXANTS -------------------------
baclofen, carisoprodol, cyclobenzaprine
dantrolene, methocarbamol, tizanidine, etc.
Exelderm, Mentax, Naftin, Oxistat, Xolegel
TOPICAL ANTI-INFLAMMATORY AGENTS--------- OPHTHALMIC ANTI-ALLERGIC & RELATED AGENTS--------------------- Tier 1 TOPICAL SCABICIDES/PEDICULICIDES ------------------- Tier 1
lindane lotion or shampoo, malathion lotion,
OTHER DERMATOLOGICALS ---------------------------- Tier 1
calcipotriene, Condylox, Elidel, imiquimod,
ANTI-GLAUCOMA AGENTS -----------------------------
brimonidine, dipivefrin, betaxolol, carteolol
Anamantle HC, Anamantle HC Forte, Anusol
latanoprost, levobunolol, metipranolol, timolol,
HC, Atopiclair, Dovonex, Fluoroplex, Ovace,
Pramosone, Protopic, Solaraze, Soriatane,
MISCELLANEOUS ANTI-INFECTIVE AGENTS-------------------------------- ANTI-INFLAMMATORY AGENTS--------------------------- ANTI-INFECTIVE AND ANTI-INFLAMMATORY COMBINATIONS --------------------------------------------- NSAIDS-----------------------------------------------------------
This document is in effect January 1, 2013. Formulary consultation and administrative support to provided by:
Engineering Efficient + Effective Drug Therapy ™
THIS CIRCULAR IS IMPORTANT AND REQUIRES YOUR IMMEDIATE ATTENTION XINHUA FINANCE LIMITED (Incorporated in the Cayman Islands with limited liability) NOTICE OF ANNUAL GENERAL MEETING A notice convening the Annual General Meeting of the Company to be held at Orchard Room, 2nd floorof Annex of Hotel Okura (2-10-4 Toranomon, Minato-ku, Tokyo) on Thursday, April 20, 2006 at 1:30 pm(Tokyo ti