La tétracycline, connue sous le nom commercial Sumycin, agit en bloquant la fixation de l’ARNt sur la sous-unité 30S ribosomale, interrompant l’élongation de la chaîne protéique bactérienne. Ce mécanisme confère une activité sur un spectre large, incluant bactéries Gram positives, Gram négatives, rickettsies et spirochètes. Sa biodisponibilité digestive varie selon la prise alimentaire et les interactions avec les ions divalents comme calcium et magnésium. Sa diffusion tissulaire est importante, notamment dans les voies respiratoires et génito-urinaires. L’élimination se fait par voie rénale et biliaire. Les effets indésirables incluent photosensibilisation, troubles digestifs et coloration dentaire en cas d’administration précoce. Les guides thérapeutiques mentionnent sumycin prix, en soulignant la nécessité de restreindre son utilisation afin de limiter les résistances acquises.

Microsoft word - new= nilkanth pharmalist1.doc

MANUFACTURERS OF: ORGANIC CHEMICALS & PHARMA INTERMEDIATES
REGD OFF: 13/14, MOHINI VILLA, M.G.ROAD, KANDIVALI (W), MUMBAI-400067.INDIA.
TEL: 0091-22-28016437/65092080/64185353/ Fax: 0091-22-28016437/23438411
Fact: Phase-II, GIDC, Vatva, Ahemdabad-382445.
Web : www.nilkanthorganics.com Email :nilkanthorganics@gmail.com
_________________________________________________________________________________________
PHARMA INTERMEDIATES
METHYL- 2-IODOBENZOATE
2. 4-(FLUORO BENZOYL) BUTYRIC A
3. PARA ANISIDINE 4. BOURDEX GP BASE
2-MERCAPTO 5- MBI
2- MERCAPTO BENZIMADZOLE
PIPERAZINE DARIVEVATES
IODINE DARIVITES
PIPERADINE DARIVEVATES
BROMINE BASE COMPOUND
PYRADINE DARIVEVATES
PHTHALIC BASE INT.
1- CHLORO METH
14 N-METHYL-1NAPHTHYLMETHYLA HCL
PARA CHLORO META CRESOL
PARA CHLORO META XYLENOL
INDOLE DARIVEVATES
BENZOIC ACID BASE INT.
NN BIS 2- CL ETHYLAMINE HCL
CIS - BROMOBENZOATE
1 H 1,2,4 TRIAZOLE 22.
SODIUM METHOXIDE SOL.
4-FLUORO NITRI BENZENE
5-ETHYL-2-PYRODYL ETHAN
3,4 DIHYDRO PYRAN
1,3 CHLORO PHENYL PIPERAZINE
METHYL NICOTINATE
2,3 DICHLORO BENZOYL CHLORIDE
29. 2,3 DI CHLORO. BENZOYL CYANIDE
SCHIFF BASE

Under our special strength in R & D and project we can provide a customized service to clients having special
needs concerning intellectual property, confidentiality and the environment.


SPECIALIZED INTERMEDIATES

1) ETHAMSYLATE BP (24) MICONAZOLE NITRATE
2) ECONAZOLE NITRATE (25) FLUNARIZINE DI HCL
3) TIMOLOL MALEATE (26) BENZYL FORMETROL
4) 2-4 (DICHLORO PHENYL) 2 (1- IMIDAZOLE) ETHANOL (MICONAZOLE INTERMEDIATE)
5) 1- (4-BENZYLOXY PHENYL)-2-(1-METHYL –2- PHENOXY ETHYLAMINO) – PROPANONE –1-HCL.
( NAK HCL) ( Used in ISOXSUPRINE )
6) NONYL AMINE (27) CINNAMYL BROMIDE
7) 2-METHYL GLUYARIC ACID
(28) CINNAMYL TRIPHRNYL PHOSPHONIUM BROMIDE

8) 5,6-DIMETHOXY –1- INDANONE (29) PHENYL CHLORO THIONOFORMATE
9) 3-AMINO –2- CYCLOHEXENE –1- ONE (30) 1,6 –DIPHENYL –1,3,5- HEXATRINE
10) 4 (-2 AMINO ETHYL) BENZOIC ACID
(31) NONYL BENZIMIDAZOLE

11) DECYL IMIDAZOLE
(32) PROTOCATACHALDEHYDE (3,4 – DIHYDR BENZALDEHYDE)

12) ISO VANILLIN
(33) 3-CHLORO PHENYL ISOTHIOCYNATE

13) 3-CYNO BENZYL BROMIDE
(34) INDOLE –2- CARBOXYLIC ACID

14) 3-BROMO –5- CHLORO SALICYLDEHYDES (35) 3,5-DICHLORO SALICYLALDEHYDE
15) 2-METHYALLYL AMINE (36) 4-CHLORO PHENYL [Haloperidol intermediate]
16)4- BROMO PHENYL [Bromoperidol intermediate] (37) 6-BROMO –2- NAPTHOICACID METHYLESTER
17) 3-METHYL BIPHENYL
(38) -BROMO CINNAMLDEHYDE

18) N- PROPYL PIPERAZINE DI HBR
(39) CYCLOHEXANONE –2- CARBETHOXYLATE

19) 3-CYNO BENZYL BROMIDE (40) 1, 1-DIMETHYL CYCLOHEXANONE
20) METHYL –2- CYCLOHEXANONE CARBOXYLATE (41) 4-CHLORO-2- BUTERO THIONONE
21) LEPLDINE OR 4-METHYL QUINOLINE (42) 4-QUINOLINE CARBOXYLIC ACID
22) 2-NAPHTHOYL CHLORIDE
(43) NICOTINIC ANHYDRIDE

23) 2,5- DIMETHYL THIOPHENE
(44) PHENYL BORONIC ACID [for simavastat )

Source: http://www.nilkanthorganics.com/other-files/pharma-list.pdf