La tétracycline, connue sous le nom commercial Sumycin, agit en bloquant la fixation de l’ARNt sur la sous-unité 30S ribosomale, interrompant l’élongation de la chaîne protéique bactérienne. Ce mécanisme confère une activité sur un spectre large, incluant bactéries Gram positives, Gram négatives, rickettsies et spirochètes. Sa biodisponibilité digestive varie selon la prise alimentaire et les interactions avec les ions divalents comme calcium et magnésium. Sa diffusion tissulaire est importante, notamment dans les voies respiratoires et génito-urinaires. L’élimination se fait par voie rénale et biliaire. Les effets indésirables incluent photosensibilisation, troubles digestifs et coloration dentaire en cas d’administration précoce. Les guides thérapeutiques mentionnent sumycin prix, en soulignant la nécessité de restreindre son utilisation afin de limiter les résistances acquises.

Microsoft word - formulary changes 2008_0108.doc

Formulary Changes 2008

Formulary Additions

Accolate

Formulary Deletions
Formulary Alternatives
Moved to third tier coverage for selected plans
Abilify……………………………………………… Clozaril*, Risperdal, Seroquel
Actonel…………………………………………… Fosamax
Adderall XR (PA for ≥ 18 years of age)………….
Adderall*, Ritalin*, Ritalin SR*, Metadate ER*, Concerta Altace………………………………………………. Prinivil*, Lotensin*, Accupril*, Vasotec* Amerge……………………………………………. Imitrex, Androderm (PA)………………………………… . . Testim (PA) Androgel (PA)……………………………………. Anzemet…………………………………………… Arthrotec…………………………………………… Voltaren* plus Cytotec* Byetta (PA)…………………………………………. Amaryl*, Diabeta*, Glucotrol*, Glynase*, Micronase*, Celebrex…………………………………………… Motrin*, Naprosyn*, Mobic*, Voltaren*, Orudis*, Clinoril*, Disalcid*, Relafen* Cipro HC…………………………………………… Ciprodex Cosopt………………………………………………. Timoptic* plus Azopt Cozaar……………………………………………… Benicar, Cymbalta (PA)……………………………………… Celexa*, Prozac*, Zoloft*, Paxil* Detrol/Detrol LA…………………………………… Ditropan* Differin…………………………………………… . Diovan……………………………………………… Benicar, Diovan HCT………………………………………. Benicar HCT, Micardis HCT FemHRT……………………………………………. Prempro, Flomax……………………………………………… Cardura*, Hytrin*, Proscar*, Uroxatral Hyzaar……………………………………………… Benicar HCT, Micardis HCT Lamictal……………………………………………. phenobarbital, Tegretol*, Tegretol XR, Carbatrol, Dilantin*, Depakene*, Depakote, Depakote ER, Neurontin* Levaquin……………………………………………. Cipro*, Lipitor……………………………………………… Zocor*, Prevachol*, Mevacor*, AltoPrev, Crestor (5mg Formulary Deletions
Formulary Alternatives
Moved to third tier coverage for selected plans
Lyrica (PA)…………………………………………. phenobarbital, Tegretol*, Tegretol XR, Carbatrol,
Dilantin*, Depakene*, Depakote, Depakote ER, Neurontin* Nasacort…………………………………………… Nexium (ST)………………………………………. Prilosec OTC™ (covered with prescription for generic copay), Pataday……………………………………………. Alaway, Zaditor OTC (covered with prescription for generic copay) Patanol……………………………………………. . Alaway, Zaditor OTC (covered with prescription for Paxil CR (ST)……………………………………… Celexa*, Prozac*, Zoloft*, Paxil* Proventil HFA……………………………………… Proair HFA (generic copay) Provigil (PA)………………………………………. Restasis…………………………………………… Strattera……………………………………………. Ritalin*, Adderall*, Concerta Topamax……………………………………………. phenobarbital, Tegretol*, Tegretol XR, Carbatrol, Dilantin*, Depakene*, Depakote, Depakote ER, Neurontin* Tricor………………………………………………. Lofibra*, Lopid*, Triglide Tussionex…………………………………………. Robitussin AC*, Hycodan* Vagifem……………………………………………. Premarin Viagra……………………………………………… All Vigamox……………………………………………. Tobrex*, Xalatan……………………………………………. Lumigan, Zaditor……………………………………………… Zaditor (requires doctor’s prescription – generic copay) Zetia………………………………………………… Zocor*, Pravachol*, Niaspan, Vytorin (10/10mg ST) Zomig, Zomig ZMT………………………………. Imitrex, Maxalt Zyprexa (PA) ……………………………………… Risperdal, (PA) indicates prior authorization required Please refer to your health plan documents regarding any limitations or exclusions that * A generic equivalent is available at the lowest copay

Source: http://www.mutualsupplement.com/documents/formulary_changes_2008.pdf