La tétracycline, connue sous le nom commercial Sumycin, agit en bloquant la fixation de l’ARNt sur la sous-unité 30S ribosomale, interrompant l’élongation de la chaîne protéique bactérienne. Ce mécanisme confère une activité sur un spectre large, incluant bactéries Gram positives, Gram négatives, rickettsies et spirochètes. Sa biodisponibilité digestive varie selon la prise alimentaire et les interactions avec les ions divalents comme calcium et magnésium. Sa diffusion tissulaire est importante, notamment dans les voies respiratoires et génito-urinaires. L’élimination se fait par voie rénale et biliaire. Les effets indésirables incluent photosensibilisation, troubles digestifs et coloration dentaire en cas d’administration précoce. Les guides thérapeutiques mentionnent sumycin prix, en soulignant la nécessité de restreindre son utilisation afin de limiter les résistances acquises.

Microsoft word - 2500.doc

MATERIAL SAFETY DATA SHEET
Date: 01/25/07
-------------------------------------------- I. PRODUCT IDENTIFICATION -------------------------------
TRADE NAME (as labeled): LATICRETE® Permacolor™ Grout

CHEMICAL FAMILY: Proprietary powder
MANUFACTURER'S NAME:
Phone number for additional information: (203) 393-0010 Date prepared or revised: 1/09 -------------------------------------------- II. HAZARDOUS INGREDIENTS ----------------------------
cement
N/A = Not applicable or available

------------------------------------------ III. HEALTH HAZARD INFORMATION -----------------------
SYMPTOMS OF OVEREXPOSURE for each potential route of exposure. (Possible Longer Term
Effects) Chronic Bronchitis, possible silicosis, or cancer if exposed to greater than permissible limits
for a prolonged period of time. Exposure to more than 5 mg/m3 without protection may cause birth
defects in pregnant women.
SIGNS AND SYMPTOMS OF EXPOSURE (Acute effects)
Inhaled: irritation to nose and throat, large doses may cause tremor or nausea. May cause damage
to mucous membranes or respiratory tract.
Contact with skin or eyes: may cause skin irritation or burns and eye irritation or burns
Absorbed through skin: Not likely to occur
Swallowed: irritation to throat, nausea, inhalation or swallowing of large doses (over 500 mg/kg of
body weight) may cause tremor or nausea
SUSPECTED CANCER AGENT?
NO: This product's ingredients are not found in the lists below.
YES: Federal OSHA NTP x IARC
MATERIAL SAFETY DATA SHEET
Date: 01/25/07
------------------------------IV. FIRST AID: EMERGENCY PROCEDURES----------------------------------------- Eye Contact: Hold eyelids apart and immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention immediately. Skin Contact: Rinse with soap and water. If irritation persists, seek medical attention Inhaled: Move to fresh air. If normal breathing does not resume, seek medical help Swallowed Seek immediate medical help. ---------------------------------------------- V. FIRE AND EXPLOSION ------------------------------------------ Flash Point method): Non-Flammable Auto ignition temperature,F: N/A Flammable limits in air, volume %: x foam x dry chemical
Special fire fighting procedures: None known.
Unusual fire and explosion hazards: None known.
----------------------------------- VI. SPILL, LEAK, AND DISPOSAL PROCEDURES -----------------------
Spill response procedures (include employee protection measures): Sweep up and return to
container. Wear gloves, long sleeves, safety eye wear, and NIOSH approved dust mask.
Preparing wastes for disposal (container types, neutralization, etc.):
NOTE: Dispose of all wastes in accordance with federal, state and local regulations.
------------------------------------------VII. Handling and Storage----------------------------------------------------------

Store in cool dry area.
MATERIAL SAFETY DATA SHEET
Date: 01/25/07
-------------------------------------- VIII. Exposure Controls and Personal Protection ------------------------------
Ventilation and engineering controls: normal ventilation
Respiratory protection (type): NIOSH approved dust mask if TLV is exceeded
Eye protection (type): safety glasses or goggles
Gloves (specify material): leather or rubber gloves
Other clothing and equipment: long sleeved clothing
Work practices, hygienic practices: normal good housekeeping
Other handling and storage requirements: None Known.
Protective measures during maintenance of contaminated equipment: See above.

------------------------------------------------ IX. PHYSICAL PROPERTIES ----------------------------
Vapor density (air=1):N/A
Evaporation rate (butyl acetate = 1): N/A Vapor pressure, mmHg at 20C: N/A Appearance and odor: grey odorless powder HOW TO DETECT THIS SUBSTANCE (warning properties of substance as a gas, vapor, dust, or mist): ---------------------------------------------------- X. REACTIVITY DATA ----------------------------------------------- Stability: x Stable Unstable Conditions to avoid: None known. Incompatibility (materials to avoid): incompatible with concentrated acids Hazardous decomposition products (including combustion products): (from burning, heating, or reaction with other materials). None known. Hazardous polymerization: May occur x Will not occur Conditions to avoid: None known. MATERIAL SAFETY DATA SHEET
Date: 01/25/07
-----------------------------------------------XI. Toxicology Information------------------------------------------------- None known. -----------------------------------------------XII. Ecological Information------------------------------------------------- None known. -----------------------------------------------XIII. Disposal Information-------------------------------------------------- Dispose in compliance with local, state, and federal regulations. ------------------------------------------------XIV. Transport Information--------------------------------------------------- No special labeling or transportation placarding is required. ------------------------------------------------XV. Regulatory Information-------------------------------------------------- All ingredients are listed on the U.S. EPA TSCA inventory of chemical substances. W.H.M.I.S. Class D.2. This product contains a chemical known to the State of California to cause cancer or reproductive harm. ------------------------------------------------XVI Other Information--------------------------------------------------------- This information is furnished without warranty, representation, inducement or license of any kind; except that it is accurate to the best of our knowledge, or obtained from sources believed by us to be accurate.

Source: http://www.laticrete.lv/res/pdf/laticrete/msds/en/material_safety_data_sheet_laticrete_permacolor.pdf