Barbara_aktuell.doc

References
Original contributions in medical and scientific journals
• Winkler C, Wirleitner B, Schroecksnadel K, Schennach H, Fuchs D. Beer down-regulates activated peripheral blood mononuclear cells in vitro. Int. Immunopharmacol. 2006; 6: 390-395. • Wirleitner B, Schroecksnadel K, Winkler C, Fuchs D. Neopterin in HIV-Infection. Mol. Immunology • Schroecksnadel K, Frick B, Winkler C, Wirleitner B, Weiss G, Fuchs D. Atorvastatin suppresses homoscysteine formation in stimulated human peripheral blood mononuclear cells. Clin. Chem Lab. • Schroecksnadel K, Winkler C, Duftner C, Wirleitner B, Schirmer M, Fuchs D. Tryptophan degradation increases with stage in patients with rheumatoid arthritis. Clin. Rheumatol. 2005; 1: 1-4. • Schroecksnadel K, Winkler C, Wirleitner B, Schennach H, Weiss G, Fuchs D. Anti-inflammatory compound resveratrol suppresses homocysteine formation in stimulated human peripheral blood mononuclear cells in vitro. Clin. Chem. Lab. Med. 2005; 43: 1084-1088. • Wirleitner B, Schroecksnadel K, Winkler C, Schennach H, Fuchs D. Resveratrol suppresses interferon- gamma-induced biochemical pathways in human peripheral blood mononuclear cells in vitro. Immunol. • Schroecksnadel K, Wirleitner B, Winkler C, Fuchs D. Monitoring tryptophan metabolism in chronic immune activation. Clin. Chim. Acta. 2005; 31 • Schroecksnadel K, Frick B, Winkler C, Wirleitner B, Schennach H, Fuchs D. Aspirin down-regulates homocysteine formation in stimulated human peripheral blood mononuclear cells. Scand. J. Immunol. • Schroecksnadel K, Winkler C, Wirleitner B, Schennach H, Fuchs D. Aspirin down-regulates tryptophan degradation in stimulated human peripheral blood mononuclear cells in vitro. Clin. Exp. Immunol. • Pellegrin K., Neurauter G, Wirleitner B, Fleming AW, Peterson VM, Fuchs D. Enhanced enzymatic degradation of tryptohan by indoleomine 2,3-dioxygenase contributes to the tryptophan-deficient state seen after major trauma. Shock. 2005; 23: 209-215. • Schroecksnadel K, Leblhuber F, Frick G, Wirleitner B, Fuchs D. Association of hypterhomocysteinemia in Alzheimer disease with elevated neopterin levels. Alzheimer Dis. Assoc. Disord. 2004; 18: 129-133. • Winkler C, Wirleitner B, Schroecksnadel K, Schennach H, Fuchs D. St. John’s wort (Hypericum perforatum) counteracts cytokine-induced tryptophan catabolism in vitro. Biol. Chem. 2004; 385: 1197- • Wirleitner B, Neurauter G, Nagl M, Fuchs D. Down-regulatory effect of N-chlorotaurine on tryptophan degradation and neopterin production in human PBMC. Immunol. Lett. 2004; 93: 143-149. • Neurauter G, Wirleitner B, Schroecksnadel K, Schennach H, Ueberall F, Fuchs D. PADMA 28 modulates interferon-gamma-induced tryptophan degradation and neopterin production in human PBMC in vitro. Int. Immunopharmacol. 2004; 4: 833-839. • Winkler C, Wirleitner B, Schroecksnadel K, Schennach H, Mur E, Fuchs D. In vitro effects of two extracts and two pure alkaloid preparations of Uncaria tomentosa on peripheral blood mononuclear cells. Planta Med. 2004; 70: 205-210. • Fries D, Streif W, Margreiter J, Klingler A, Kuhbacher G, Schobersberger W, Wirleitner B, Innerhofer P. The effects of perioperatively administered crystalloids and colloids on concentrations of molecular markers of activated coagulation and fibrinolysis. Blood Coagul. Fibrinolysis. 2004; 15: 213-219. • Wirleitner B, Sperner-Unterweger B, Fuchs D. Statins to reduce risk of depression. J. Am. Coll. Cardiol. • Schroecksnadel K, Frick B, Wirleitner B, Winkler C, Schennach H, Fuchs D. Moderate hyperhomocysteinemia and immune activation. Curr. Pharm. Biotechnol. 2004; 5:107-118. • Frick B, Schroecksnadel K, Neurauter G, Wirleitner B, Artner-Dworzak E, Fuchs D. Rapid measurement of total plasma homocysteine by HPLC. Clin. Chim. Acta 2003; 331: 19-23. • Frick B, Neurauter G, Diez-Ruiz A, Schroecksnadel K, Wirleitner B, Fuchs D. Neopterin a y productos oxidativos en sangre de pacientes con varias formas de demencia. Investig. Clin. (Spain) 2003; 5: 110- • Hoffmann G, Wirleitner B, Fuchs D. Potential role of immune system activation-associated production of neopterin derivatives in humans. Inflamm. Res. 2003; 52: 313-321. • Neurauter G, Wirleitner B, Laich A, Schennach H, Weiss G, Fuchs, D. Atorvastatin suppresses interferon-gamma-induced neopterin formation and tryptophan degradation in human peripheral blood mononuclear cells and in monocytic cell lines. Clin. Exp. Immunol. 2003; 131: 264-267. • Schroecksnadel K, Frick B, Kaser S, Wirleitner B, Ledochowski M, Mur E, Herold M, Fuchs D. Moderate hyperhomocysteinaemia and immune activation in patients with rheumatoid arthritis. Clin. • Schroecksnadel K, Frick B, Winkler C, Leblhuber F, Wirleitner B, Fuchs D. Hyperhomocysteinemia and immune activation. Clin. Chem. Lab. Med. 2003; 41:1438-1443. • Schroecksnadel K, Frick B, Wirleitner B, Schennach H, Fuchs D. Homocysteine accumulates in supernatants of stimulated human peripheral blood mononuclear cells. Clin. Exp. Immunol. 2003; 134: • Wirleitner B, Neurauter G, Schroecksnadel K, Frick B, Fuchs D. Determination of tryptophan and kynurenine to estimate activity of indoleamine (2,3)-dioxygenase. Lab. Med. Intern. 2003; 20: 11-14. • Wirleitner B, Neurauter G, Schroecksnadel K, Frick B, Fuchs D. Interferon-γ-induced conversion of tryptophan: immunologic and neuropsychiatric aspects. Curr. Med. Chem. 2003; 10: 1581-1591. • Wirleitner B, Obermoser G, Böck G, Neurauter G, Schennach H, Sepp N, Fuchs D. Induction of apoptosis in human blood T cells by 7,8-dihydroneopterin: the difference between healthy controls and patients with systemic lupus erythematosus. Clin. Immunol. 2003; 107: 152-159. • Wirleitner B, Rudzite V, Neurauter G, Murr C, Kalnins U, Erglis A, Trusinskis K, Fuchs D. Immune activation and degradation of tryptophan in coronary heart disease. Eur. J. Clin. Invest. 2003; 33: 550- • Wirleitner B, Schroecksnadel K, Winkler C, Frick B, Fuchs D. In vivo determination of oxidative stress. Aktuel. Ernähr. Med. 2003; 28: 363-370. • Enzinger C, Wirleitner B, Lutz C, Böck G, Tomaselli B, Baier G, Fuchs D, Baier-Bitterlich G. 7,8- Dihydroneopterin induces apoptosis of Jurkat T-lymphocytes via a bcl-2-sensitive pathway. Eur. J. Cell • Enzinger C, Wirleitner B, Spöttl N, Böck G, Fuchs D, Baier-Bitterlich G. Reduced pteridine derivatives induce apoptosis in PC12 cells. Neurochem. Int. 2002; 41: 71-78. • Laich A, Neurauter G, Wirleitner B, Fuchs D. Degradation of serum neopterin during daylight exposure. Clin. Chim. Acta 2002; 322: 175-178. • Murr C, Widner B, Wirleitner B, Fuchs D. Neopterin as a marker for immune system activation. Curr. • Widner B, Enzinger C, Laich A, Wirleitner B, Fuchs D. Hyperhomosysteinemia, pteridines and oxidative stress. Curr. Drug Metab. 2002; 3: 225-232. • Wirleitner B, Reider D, Ebner S, Böck G, Widner B, Jaeger M, Schennach H, Romani N, Fuchs D. Monocyte-derived dendritic cells release neopterin. J. Leukoc. Biol. 2002; 72: 1148-1153. • Amadori A, Wirleitner B, Diez-Ruiz A, Veronese A, Chieco-Bianchi L, Fuchs D. Neopterin production in SCID mice injected with human peripheral mononuclear cells. Immunobiology 2001; 203: 642-649. • Enzinger C, Wirleitner B, Bock G, Baier-Bitterlich G, Fuchs D. Influence of cytokines tumor necrosis factor-alpha and interferon-gamma on signaling cascades associated with apoptosis in rat PC12 cells. Neurosci. Lett. 2001; 316: 157-160. • Fuchs D, Jaeger M, Widner B, Wirleitner B, Artner-Dworzak E, Leblhuber F. Is hyperhomocysteinemia due to the oxidative depletion of folate rather to insufficient dietary intake? Clin. Chem. Lab. Med. 2001; • Wirleitner B, Czaputa R, Öttl K, Böck G, Widner B, Spöttl N, Reibnegger G, Baier G, Fuchs D, Baier- Bitterlich G. Induction of apoptosis by 7,8-dihydroneopterin: Involvement of hydroxyl radical formation. Immunobiology 2001; 203: 629-641. • Zvetkova E, Wirleitner B, Tram NT, Schennach H, Fuchs D. Aqueous extracts of Crinum latifolium (L.) and Camellia sinensis show immunomodulatory properties in human peripheral blood mononuclear cells. Int. Immunopharmacol. 2001; 1: 2143-2150. • Gruber A, Murr C, Wirleitner B, Werner-Felmayer G, Fuchs D. Histamine suppresses neopterin production in the human myelomonocytoma cell line THP-1. Immunol. Lett. 2000, 72: 133-136. • Speth C, Stöckl G, Fuchs D, Wirleitner B, Widner B, Würzner R, Mohsenipur I, Dierich MP. Inflammation marker 7,8-dihydroneopterin induces apoptosis of neurons and glial cells: a potential contribution to neurodegenerative processes. Immunobiology 2000; 202: 460-476. • Widner B, Mayr C, Wirleitner B, Fuchs D. Oxidation of 7,8-dihydroneopterin by hypochlorous acid yields neopterin. Biochem. Biophys. Res. Commun. 2000; 275: 307-311. • Widner B, Sepp N, Kowald E, Ortner U, Wirleitner B, Fritsch P, Baier-Bitterlich G, Fuchs D. Enhanced tryptophan degradation in systemic lupus erythematosus. Immunobiology 2000, 201: 621-630. • Widner B, Wirleitner B, Baier-Bitterlich G, Weiss G, Fuchs D. Cellular immune activation, neopterin production, tryptophan degradation and the development of immunodeficiency. Arch. Immunol. Ther. • Wirleitner B, Kowald E, Widner B, Ortner U, Baier-Bitterlich G, Sepp N, Fuchs D. Soluble Fas ligand in neopterin in patients with systemic and cutaneous lupus erythematosus. Pteridines 2000; 11: 85-89. • Hobisch-Hagen P, Wirleitner B, Mair J, Luz G, Innerhofer P, Frischhut B, Ulmer H, Schobersberger W. Consequences of acute normovolaemic haemodilution on haemostasis during major orthopaedic surgery. Br. J. Anaesth. 1999; 82: 503-509. • Hoffmann G, Rieder J, Smolny M, Seibel M, Wirleitner B, Fuchs D, Schobersberger W. Neopterin- induced expression of intercellular adhesion molecule-1 (ICAM-1) in type II-like alveolar epithelial cells. Clin. Exp. Immunol. 1999; 118: 435-440. • Murr C, Fuith L, Widner B, Wirleitner B, Baier-Bitterlich G, Fuchs D. Increased neopterin concentrations in patients with cancer: indicator of oxidative stress? Anticancer Res. 1999; 19: 1721- • Murr C, Widner B, Wirleitner B, Baier-Bitterlich G, Fuchs D. Neopterin als Prognoseparameter bei malignen Tumorerkrankungen. J. Lab. Med. 1999; 23(10): 545-549. • Nassonov EL, Samsonov MY, Wirleitner B, Tilz G, Fuchs D. Neopterin in autoimmune rheumatic diseases. Pteridines 1999; 10: 119-124. • Oettl K, Wirleitner B, Baier-Bitterlich G, Grammer T, Fuchs D, Reibnegger G. Formation of oxygen radicals in solutions of 7,8-dihydroneopterin. Biochem. Biophys. Res. Commun. 1999; 264: 262-267. • Spöttl N, Wirleitner B, Böck G, Widner B, Fuchs D, Baier-Bitterlich G. Reduced pteridine derivatives induce apoptosis in human neuronal NT2/hNT cells. Immunobiology 1999/2000; 201: 478-491. • Widner B, Murr C, Wirleitner B, Mayr C, Spöttl N, Baier-Bitterlich G, Fuchs D. The importance of neopterin as a laboratory diagnostic marker of immune activation. Pteridines 1999; 10: 101-111. • Widner B, Wirleitner B, Baier-Bitterlich G, Murr C, Fuchs D. Neopterin – a laboratory diagnostic parameter for immune activation. FONS, Infromacni Bulletin, Ceska Spolecnost Klinicke Biochemie • Hoffmann G, Kenn S, Wirleitner B, Deetjen C, Frede S, Smolny M, Rieder J, Fuchs D, Baier-Bitterlich G, Schobersberger W. Neopterin iduces neitic oxide-dependent apoptosis in rat vascular smooth muscle cells. Immunobiology 1998; 199: 63-73. • Widner B, Baier-Bitterlich G, Wede I, Wirleitner B, Fuchs D. Neopterin derivatives modulate the nitration of tyrosine by peroxynitrite. Biochem. Biophys. Res. Commun. 1998; 248: 341-346. • Widner B, Baier-Bitterlich G, Wede I, Wirleitner B, Wachter H, Fuchs D. Neopterin: Indicator of oxidative stress and part of the cytotoxic armature of activated macrophages in humans. Pteridines • Wirleitner B, Baier-Bitterlich G, Widner B, Wachter H, Fuchs D. 7,8-Dihydroneopterin induce apoptosis in Jurkat T lymphocytes: a comparison with anti-Fas and hydrogen peroxide-mediated cell death. Biochem. Pharmacol. 1998; 56: 1181-1187. • Dietl P, Haller T, Wirleitner B, Friedrich F. Two different store-operated calcium entry pathways in MDCK cells. Cell Calcium 1996; 20: 11-19. • Schobersberger W, Wirleitner B, Puschendorf B, Koller A, Villiger B, Frey W, Mair J. Influence of an ultramarathon race at moderate altitude on coagulation and fibrinolysis. Fibrinolysis 1996; 10: 37-42. • Schobersberger W, Hoffmann G, Hobisch-Hagen P, Boeck G, Voelkl H, Baier-Bitterlich G, Wirleitner B, Wachter H, Fuchs D. Neopterin and 7,8-dihydroneopterin induce apoptosis in the rat alveolar epithelial cell line L2. FEBS-Lett. 1996; 397: 263-268. • Dietl P, Haller T, Wirleitner B, Voelkl H, Friedrich F, Striessnig J. Activation of L-type calcium channels after purinoceptor stimulation by ATP in an alveolar epithelial cell (L2). Am. J. Physiol. 1995; 269: Book contributions
• Fuchs D, Baier-Bitterlich G, Widner B, Wirleitner B, Wachter H, Schobersberger W. Neopterin derivatives interfere with redox-regulated intracellular pathways. In: Chemistry and Biology of Pteridines and Folates 1997 (Eds. Pfleiderer W, Rokos H) Blackwell Science Berlin, Wien, Oxford, Edinburgh, Boston, London, Melbourne, Paris, Tokyo, p 797-802 • Widner B, Baier-Bitterlich G, Wede I, Wirleitner B, Wachter H, Fuchs D. Neopterin and 7,8- dihydroneopterin influence the reaction of peroxynitrite with tyrosine. In: Chemistry and Biology of Pteridines and Folates 1997 (Eds. Pfleiderer W, Rokos H) Blackwell Science Berlin, Wien, Oxford, Edinburgh, Boston, London, Melbourne, Paris, Tokyo, p 807-810 • Wiedermann FJ, Schobersberger W, Widner B, Fries D, Wirleitner B, Hoffmann G, Fuchs D. Laboratory Markers to support early diagnosis of infection and inflammation. In: Multiple Organ Failure: Pathophysiology, Prevention, and Therapy. 2000 (Eds. Baue AE, Faist E, Fry DE) Springer- Verlag New York, Berlin, Heidelberg, p 477-491 • Zangerle R, Baier-Bitterlich G, Sarcletti M, Widner B, Wirleitner B, Fuchs D. Pharmacology of neopterin in HIV-1 infection and AIDS. In: Pharmacology of HIV infection and AIDS. 2000 (Eds. Fuchs D, • Baier-Bitterlich G, Spöttl N, Wirleitner B, Widner B, Fuchs D. Immune stimulation, apoptosis and HIV infection. In: Pharmacology of HIV infection and AIDS. 2000 (Eds. Fuchs D, Aruoma OI) OICA Selected contributions on international conferences and talks
Wirleitner B, Schroecksnadel K, Winkler C, Schennach H, Fuchs D. Inhibition of T-cell activation and cytokine production by tetrahydropteridines. 21th International Winter-Workshop on Biochemical and Clinical Aspects of Pteridines 2004, St. Christoph, Österreich. Wirleitner B, Schroecksnadel K, Winkler C, Schennach H, Fuchs D. Antioxidant resveratrol interferes with Th1-type immune activation cascades. 21th International Winter-Workshop on Biochemical and Clinical Aspects of Pteridines 2004, St. Christoph, Österreich. Wirleitner B, Schroecksnadel K, Winkler C, Fuchs D. Antioxidant resveratrol suppresses cytokine-induced activation of IDO. Ibc 2003 Joint meeting of clinical biochemists 18.-20. September 2003, Innsbruck, Wirleitner B, Schroecksnadel K, Winkler C, Fuchs D. Influence of tetrahydro-pteridines on cytokine- production of activated T-cells. Österr. Gesellschaft f. Allergologie und Immunologie (ÖGAI) December 4-6 Wirleitner B, Neurauter G, Winkler C, Gottardi W, Nagl M, Fuchs D. N-Chlorotaurine downregulates neopterin production and tryptophan degradation in human PBMCs. Österr. Gesellschaft f. Allergologie und Immunologie (ÖGAI) December 4-6 2003, Salzburg, Österreich. Wirleitner B, Neurauter G, Frick B, Fuchs D. Neopterin derivatives trigger apoptosis in peripheral blood T cells. 20th International Winter-Workshop on Biochemical and Clinical Aspects of Pteridines. 23. Februar - 2. März 2002, St. Christoph, Österreich [Pteridines 2002; 13: 60-61] Wirleitner B, Neurauter G, Frick B, Fuchs D. Neopterin and cardiovascular risk. 20th International Winter- Workshop on Biochemical and Clinical Aspects of Pteridines. 23. Februar -2. März 2002, St. Christoph, Wirleitner B, Fuchs D. Monocyte/macrophage derived 7,8-dihydroneopterin: Trigger of apoptosis in isolated human blood T cells. Österr. Gesellschaft f. Biochemie und Molekularbiologie (ÖBGM) 16.-18. September Wirleitner B, Neurauter G, Frick B, Schröcknadel K, Schennach H, Böck G, Fuchs D. 7,8-Dihydroneopterin: Trigger of apoptosis in isolated human blood T cells. Österr. Gesellschaft f. Allergiologie und Immunologie (ÖGAI) 21.-23. November 2002, Innsbruck, Österreich. Wirleitner B, Enzinger C, Widner B, Fuchs D. Measurement of neopterin concentrations to monitor cellular immune activation and oxidative stress. International Winter-Workshop on Biochemical and Clinical Aspects of Pteridines. 12.-19. Februar 2000, St. Christoph, Österreich [Pteridines 2001; 12: 86-87] Wirleitner B, Jaeger M, Werner ER, Fuchs D. Comparison of urinary neopterin concentrations in individuals with household contact. International Winter-Workshop on Biochemical and Clinical Aspects of Pteridines. 12.-19. Februar 2000, St. Christoph, Österreich. [Pteridines 2001; 12: 25-26] Wirleitner B, Zwetkowa E, Tram NT, Schennach H, Fuchs D. Immunomodulatory effect of aqueous extracts of Vietnamese Crinum latifolium (L.) and other teas in human peripheral blood mononuclear cells. International Winter-Workshop on Biochemical and Clinical Aspects of Pteridines. 12.-19. Februar 2000, St. Christoph, Österreich. [Pteridines 2001; 12: 26] Wirleitner B, Kowald E, Widner B, Obermoser G, Baier-Bitterlich G, Sepp N, Fuchs D. Serum levels of soluble Fas ligand in patients with systemic and cutaneous discoid lupus erythematosus. 6th International Lupus Conference 24.-28. März 2001, Barcelona, Spanien. [Lupus 2001, 10(1): 29] Wirleitner B, Reider D, Ebner S, Widner B, Romani N, Fuchs D. Dendritic cells and neopterin production. 15th annual meeting of the European macrophage society (EMS) 30. August -1. September 2001, Wien, Wirleitner B, Zvetkova E, Tram NT, Schennach H, Fuchs D. Immunomodulatory effet of crinum latifolium (L.) and Camellia sinensis on human PBMCs. Österr. Gesellschaft f. Allergiologie und Immunologie (ÖGAI) 8.-10. November 2001, Wien, Österreich. Wirleitner B, Mayr C, Spöttl N, Baier-Bitterlich G, Fuchs D. Effects of neopterin derivatives on peripheral blood-derived T-lymphocytes. 19th International Winter-Workshop on Biochemical and Clinical Aspects of Pteridines. 12.-19. Februar 2000, St. Christoph, Österreich. [Pteridines 2000; 11: 26] Wirleitner B, Romani N, Widner B, Reider D, Ebner S, Fuchs D. Neopterin is released from activated human dendritic cells. 13th Symposium on Molecular Biology of Hematopoesis and Treatment of Leukemia and Cancer, 14.-18. Juli 2000, New York, USA. [Acta Haematol. 2000; 103(Suppl 1): 9] Wirleitner B, Zvetkova E, Tram NTN, Schennach H, Fuchs D. Crinum latifolium (L.) and Camellia sinensis: Immunmodulatory effects of plant extracts. Jahresabschlusstreffen §67 Abteilung Inflammation Univ.-Kinik für Anästhesie und Intensivmedizin Innsbruck, 2. Dezember 2000, Innsbruck, Österreich. Wirleitner B, Kowald E, Spöttl N, Widner B, Mayr C, Sepp N, Fuchs D, Baier-Bitterlich G. Impact of 7,8- dihydroneopterin on oxidative stress and FasL expression in vitro and in vivo. 18th International Winter- Workshop on Biochemical and Clinical Aspects of Pteridines and 11th International Conference on Pteridines and Related Biogenic Amines. 6.-13. März 1999, St. Christoph, Österreich. [Pteridines 1999; 10: Wirleitner B, Czaputa R, Öttl K, Reibnegger G, Fuchs D, Baier-Bitterlich G. ESR detection of oxygen radicals in solutions of 7,8-dihydroneopterin. 18th International Winter-Workshop on Biochemical and Clinical Aspects of Pteridines and 11th International Conference on Pteridines and Related Biogenic Amines. 6.-13. März 1999, St. Christoph, Österreich. [Pteridines 1999; 10: 73] Wirleitner B, Reider D, Ebner S, Widner B, Romani N, Fuchs D. Human dendritic cells are a source of neopterin. Joint symposium: Societa italiani di Immunologia and Austrian Society of Allergiology and Immunology. 16.-18. Juli 1999, Udine, Italien. [Minerva Biotecnologica 1999; 11: 35] Wirleitner B, Kowald E, Sepp N, Widner B, Baier-Bitterlich G, Fuchs D. Serum neopterin correlates with soluble Fas ligand in systemic lupus erythematosus. Joint symposium: Societa italiani di Immunologia and Austrian Society of Allergiology and Immunology. 16.-18. Juli 1999, Udine, Italien. [Minerva Biotecnologica Wirleitner B, Kowald E, Widner B, Sepp N, Baier-Bitterlich G, Fuchs D. Serum soluble Fas-ligand and neopterin concentrations in patients with lupus erythematosus. International Conference on oxidative stress in skin biology and medicine. 13.-17. September 1999, Attiki, Griechenland. Wirleitner B, Widner B, Baier-Bitterlich G, Fuchs D. Pteridines, new functional aspects. XIV. National Congress of Anatomy, Histology and Embryology with International Participation, 17.-19. September 1999, Wirleitner B, Czaputa R, Spöttl N, Widner B, Öttl K, Reibnegger G, Fuchs D, Baier-Bitterlich G. Neopterin, 7,8-Dihydroneopterin und oxidativer Stress. 3. Patscher Gespräche 7. November 1998, Patsch, Österreich. Wirleitner B, Reider D, Ebner S, Widner B, Romani N, Fuchs D. Human dendritic cells produce neopterin. Jahrestagung der Österr. Gesellschaft f. Allergiologie und Immunologie (ÖGAI) 19.-21. November 1999, Wirleitner B, Baier-Bitterlich G, Boeck G, Wachter H, Fuchs D. Comparison of 7,8-dihydroneopterin- induced apoptosis in Jurkat T-lymphocytes with anti-Fas- and hydrogen peroxide-mediated cell death. 17th International Winter-Workshop on Biochemical and Clinical Aspects of Pteridines. 14.-21. Februar 1998, St. Christoph, Österreich. [Pteridines 1998; 9: 171] Wirleitner B. Neopterin in der Kardiologie. 2. Patscher Gespräche 25.-26. April 1998, Patsch, Österreich Wirleitner B, Spöttl N, Böck G, Widner B, Baier-Bitterlich G, Fuchs D. Role of 7,8-dihydroneopterin in T-cell apoptosis and HTLV-1 transcription in vitro. European Association For Cancer Research 15th meeting 15.- Wirleitner B, Spöttl N, Böck G, Widner B, Fuchs D, Baier-Bitterlich G. Potential role of 7,8- Dihydroneopterin in T-cell leukemia. Gemeinsame Jahrestagung der Österreichischen Biochemischen Gesellschaft und der Österreichischen Gesellschaft für Genetik und Gentechnik. 21.-23. September 1998, Wirleitner B, Baier-Bitterlich G, Baier G, Wachter H, Fuchs D. 7,8-Dihydroneopterin and its role in activated cell-mediated immunity and HTLV-1. 16th International Winter-Workshop on Biochemical and Clinical Aspects of Pteridines. 16.-22. Februar 1997, St. Christoph, Österreich. [Pteridines 1997; 8: 55-56] Wirleitner B. Lunge und Apoptose. 27. Mai 1997. Universitätsklinik Innsbruck, Abteilung für Anästhesie und Wirleitner B, Baier-Bitterlich G, Baier G, Fuchs D, Wachter H. 7,8-Dihydroneopterin and its role in activated cell-mediated immunity and HTLV-1. 8th International conference on human retrovirology: HTLV. 9.-13. Wirleitner B, Baier-Bitterlich G, Fuchs D, Herpfer I, Widner B, Schobersberger W. Apoptose in den L2- Zellen durch Pteridine. 1. Patscher Gespräche der Arbeitsgruppe ‘Inflammation’ 4. Oktober 1997, Patsch, Österreich. [Berichte der ÖGKC 1998; 21/2: 49-50]

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