Microsoft word - programme 7mars12

1st session: New aspects of cell metabolism during IRI
Chairs:
Keynote lecture Invited speaker: Thierry Hauet (Poitiers, France) O1 – 0002 An angiogenic response activated by the unfolded protein response during renal ischemia independently of HIF-1alpha N. Bouvier, S. Fougeray, E. Thervet, N. Pallet (Paris, France) O2 – 0014 Upregulation of HIF-1 alpha attenuates hypoxia/reoxygenation injury through HIF-1 alpha -iNOS-PGC-1alpha pathway Y. Guo, L. Feng, T. Yang, J. Shan, G. Sun, S. Li, Y. Li (Chengdu, China) O3 – 0076 PKC alpha/beta inhibition attenuates hypoxia induced interstitial renal fibrosis and inflammation via reduced activation of TGF-beta signaling X. Lu, S. Rong, N. Shushakova, J. Menne, T. Kirsch, H. Haller, F. Güler (Hannover, Germany) O4 – 0050 Cyclosporin A and Metformin inhibit ischemia-reperfusion injury on INS-1 cells through permeability transition pore inhibition. S. Lablanche, C. Cottet, F. Lamarche, P-Y. Benhamou, E. Fontaine (Grenoble, France) O5 – 0015
Transition from reversible to irreversible injury following prolonged myocardial hypothermic
preservation. Implication of mitochondrial permeability transition pore (MPTP) opening.
F. Collet, L. Sebbag, J-F. Obadia, M. Ovize, R. Ferrera (Lyon, France)
O6 – 0033 Hypercholesterolemia promotes intrarenal remodeling in a porcine auto-transplanted kidney model. F. Favreau, N. Chatauret, S. Giraud, W. Hebrard, S. Joffrion, J. Cau, T. Hauet (Poitiers, France) 2nd session: Immunological consequences of IRI
Chairs:
Keynote Lecture Invited speaker: Stefan G. Tullius (Boston, USA) O7 – 0023
Involvement of IgM natural antibodies in renal ischaemia reperfusion injury: a
potential new therapeutic target?
D. Ferenbach, D. Kluth, J. Hughes (Edinburgh, UK)
O8 – 0046
IL-17 producing unconventional Tcells contribute to hepatic ischemia reperfusion injury
E. Eggenhofer, M-H. Dahlke, M. Melter, M. Scherer, H-J. Schlitt, E. K Geissler (Regensburg, Germany)
O9 – 0011
IL-33 exacerbates liver ischemia-reperfusion injury
Z. Ping, X. Li, Y. Lin, D. Lihua, Y. Yan, F. Min, G. Feili, Y. Jun (Yichang City, China)
O10 – 0060
Feasibility of continuous ex vivo kidney perfusion with mesenchymal stem cells to prevent
ischemia-reperfusion injury in mice
P. Renner, E. Eggenhofer, F. Popp, E. Geissler, H-J. Schlitt, M-H. Dahlke (Regensburg, Germany)
O11 – 0008 Cultured human MSCs secretome contains anti inflammatory cytokines and reduces in vitro ischemia reperfusion lesions and T lymphocyte proliferation after allogeneic stimulation. D. Angoulvant, C. Lequeux, L. Denis, M. Abrial, F. Ivanes, V. Dubois, T. Bejan-Angoulvant, R. Ferrera, J. Bienvenu, M. Ovize, L. Sebbag (Tours, France) O12 – 0059
Involvement of HMGB1 alarmin and IL33/ST2 pathway after ischemia reperfusion in human renal
transplantation
A. Thierry, S. Giraud, A. Robin, V. Ameteau, F. Bridoux, G. Touchard, A. Herbelin, T. Hauet, J-M. Gombert
(Poitiers, France)
12h30 – 13h00: LUNCH
13h15 – 14h15: Symposium ORS
14h30
3rd session: New trends for additives to preservation solutions
Chairs:
Keynote Lecture Invited speaker: Raphael Thuillier (Poitiers, France) O13 - 0032
Kidney preservation with cardiotrophin-1 prevents ischemia/reperfusion injury and inflammatory
response in a syngeneic rat kidney transplant model.
M-B. García-Cenador, J-M. López-Novoa, M-P. de Obanos, J. Ruiz, J-R. Sanz-Gimenez-Rico, J-F. López
Marcos, F-J. García-Criado (Salamanca, Spain)
O14 – 0074 Superior lung preservation with a polyethylene glycol based solution in a porcine single lung transplant model A. Olland, A. Neyrinck, M. Benahmed, T. Boogmans, A. Stanzi, K. Elbayed, S. Wauters, G. Verleden, I. Namer, D. Van Raemdonck (Leuven, Belgium) O15 – 0013 Intraluminal polyethylene glycol stabilizes the tight junctions and improves intestinal preservation in the rat M. Oltean, E. Björkman, A. Casselbrand, M. Joshi, M. Olausson (Gothenburg, Sweden) O16 – 0031
Impact of preservation solution on grafts and postoperative organ failures following liver
transplantation.
H. Brisson, C. Arbelot, C. Vezinet, Q. Lu, D. Eyraud, E. Savier, C. Parizot, J-C. Vaillant, L. Hannoun, G.
Gorochov, J-J. Rouby (Paris, France)
O17 - 0037 Potential benefits of the supplementation of machine perfusion solution with Arenicola Marina hemoglobin for the preservation of porcine kidney grafts subjected to warm ischemia. P-O. Delpech, N. Chatauret, W. Hébrard, S. Joffrion, D. Dutheil, F. Zal, T. Hauet (Poitiers, France) O18 – 0064 The novel mitochondria-targeted antioxidant MitoQ ameliorates renal ischaemia reperfusion injury in a murine model A. Dare, T. Prime, A. Logan, E. Bolton, J-A. Bradley, K. Saeb-Parsy, M. Murphy (Cambridge, UK) 4th session: Machine perfusion: Why and How ?
Chairs:
Keynote Lecture Invited speaker: Henri Leuvenink (Groningen, The Netherlands) O20 – 0044 Coating of the vessel wall with macromolecular heparin during cold machine perfusion A. Sedigh, R. Larsson, G. Tuvfeson, T. Lorant (Uppsala, Sweden) O21 – 0030 Pneumatic control and monitoring for kidney perfusion in a NMR compatible system R. Ruttimann, F. Lazeyras, A. Nastasi, L. Buhler, P. Morel, J-B. Buchs (Geneva, Switzerland) O19 – 0041 One-year transplantation results of kidneys preserved by machine perfusion – LifePort Kidney Transporter versus Waters RM3 - Prospective study M. Wszola, P. Domagala, P. Diuwe, A. Kwiatkowski, L. Gorski, R. Kieszek, A. Berman, A. Perkowska-Ptasinska, M. Durlik, L. Paczek, A. Chmura (Warsaw, Poland) O22 – 0040 The final showdown: Preclinical comparison between perfusion machines ORS Lifeport and waters RM3 R. Codas, R. Thuillier, P-O. Delpech, B. Barrou, L. Badet, T. Hauet (Poitiers, France) 17h45 – 18h45: Poster session with wine and cheese New aspects of cell metabolism during IRI / Immunological consequences of IRI
Chairs:
New trends for additives to preservation solutions / Machine perfusion: Why and How ?
Chairs:
Management of brain dead donors / Donors after cardiocirculatory death Chairs: Organ Ex vivo repair / Pre/Post Conditioning Chairs: CONGRESS DINNER at the Kadelicescope in the Futuroscope Park 8h30 5th session: Management of brain dead donors Chairs: Keynote Lecture
Invited speaker: Rutger Ploeg (Oxford, UK)
“The success of transplantation begins before donation”

O23 – 0029
Secretory Leukocyte Protease Inhibitor Decreases Renal Ischemia Reperfusion Injury
D. Guerrieri, N. Ambrosi, H. Romeo, F. Cicora, F. Toniolo, P. Cicora, C. Incardona, E. Chuluyan (Buenos
Aires, Argentina)
O24 – 0066
Donor pretreatment with methylprednisolone reduces brain-death induced renal injury before
organ retrieval
P. Ottens, J. Damman, B. Liu, M. Seelen, H. Van Goor, S. Veldhuis, R. Ploeg, H. Leuvenink (Groningen,
The Netherlands)
O25 – 0069
Angiopoietin in living and deceased brain dead kidney donors
W-H. Westendorp, L-G. Koudstaal, J. Damman, J.G. Burgerhof, M-A. Seelen, H. Van Goor, R-J. Ploeg,
H-G. Leuvenink (Groningen, The Netherlands)
O26 – 0061 Effect of preconditioning with triiodothyronine on renal ischemia-reperfusion injury C. Ferreyra Lanatta, R. Pérez Abud, F. O´Valle, J-M. Osorio, F. Vargas, I. Rodriguez, A. Osuna (Granada, Spain) 6th session: Donors after cardiocirculatory death Chairs: Keynote Lecture Management of uncontrolled DCD: Invited speakers: Benoît Barrou (kidney)(Paris, France), Constantino Fondevila (liver)(Barcelona, Spain) Management of controlled DCD: Invited speaker: Diethard Monbaliu (Leuven, Belgium) O27 – 0021 Randomised controlled trial of the effects of hydrogen sulphide in renal ischaemia reperfusion injury. J. P. Hunter, S. A Hosgood, M. Patel, M. L. Nicholson (Leicester, UK) O28 – 0027
Non-heart-beating donors: preliminary study on an isolated perfused swine heart harvested after
20 minutes of normothermic ischemia
A. Piccardo, M. Desrois, E. Zogheib, C. Dalmasso, C. Lan, D. Fourré, M. Bernard, T. Caus (Amiens,
France)
O29 – 0056
Cardiac Tolerance to Warm, Global Ischemia is improved with Mild Hypothermia Following
Ischemic Arrest
M. Stadelmann, M. Dornbierer, D. Clément, B. Gahl, F. Dick, T. Carrel, H. Tevaearai,
S. Longnus (Berne, Switzerland)
O30 – 0071 Outcome after liver transplantation using controlled donation after cardiac death donors: A single-center experience N. Meurisse, S. Vanden Bussche, I. Jochmans, V. Heedfeld, J. Francois, B. Desschans, G. Van Helleputte, N. Grossen, D. Claes, J. De Roey, S. Dirix, R. Aerts, W. Laleman, S. Van der merwe, C. Verslype, D. Cassiman, W. Vansteenbergen, F. Nevens, J. Pirenne, D. Monbaliu (Leuven, Belgium) O31 – 0024 Kidney Graft Quality after Donation from Uncontrolled Deceased Donors After Cardiac Arrest R.Codas, W. Hanf, V. Meas-Yedid, B. Mac-Gregor, J. Berthiller, A. Hadj-Aissa, L. Badet, E. Morelon (Lyon, France) O32 – 0078
Impact of delayed graft function on kidney graft survival from donors after cardiocirculatory death
R.Thuret, C. Billault, F. Thibault, E. Vanglabeke, K. Fehri, S. Bart, N. Arzouk, V. Gueutin, S. Hacini, S.
Ourahma, M.O. Bitker, B. Barrou (Paris, France)
O33 – 0054 New model of kidney donation from uncontrolled donors O. Reznik, A. Scvortcov, A. Reznik, S. Bagnenko (St Petersburg, Russia) O34 – 0070 Kidney donation after circulatory death has not increased kidney transplant activity in Belgium - a comparative analysis with the Netherlands between 1995-2010 I. Jochmans, D. Monbaliu, A. Rahmel, J. Pirenne (Leuven, Belgium) 7th session: Organ Ex vivo repair Chairs: Keynote Lecture Invited Speakers: Dirk Van Raemdonck (lungs)(Leuven, Belgium), Peter Friend (liver)(Oxford, UK) O35 – 0036 Tissue engineering for ex vivo repair of ischemically damaged tubule epithelium L. Brasile, P. Glowacki, B. Stubenitsky (New-York, USA) O36 – 0019 The first clinical series of normothermic perfusion in marginal donor kidney transplantation S. A Hosgood, M. L Nicholson (Leicester, UK) O37 – 0020 The biological effects of normothermic kidney perfusion on ischaemia reperfusion injury S. A Hosgood, T. Richards, M. Patel, M. L Nicholson (Leicester, UK) O38 – 0035 Potential for ex vivo renal repair L. Brasile, P. Glowacki, B. Stubenitsky (New-York, USA) 8th session: Pre/Post Conditioning Chairs: O39 – 0017
Diazoxide attenuates ischemia/reperfusion injury via upregulation of heme oxygenase-1 after liver
transplantation in rats
HF. Huang, Z. Zeng, F. He, MQ. Chen (Kunming, China)
O40 – 0007 Effects of anaesthetic preconditioning plus postconditioning with sevoflurane in warm liver ischemia/reperfusion injury in rats J. Avancini Rocha Filho, E.R. Ramos Figueira, B. Beck Schimmer, V. Oliveira Andre, M. Felipe de Souza Buto, M. Nakatani, F.J. Gonçalves Prado, M.J. Carvalho Carmona, P-A. Clavien, L.A. Carneiro D’Albuquerque (Sao Paulo, Brazil) O41 – 0047 Protective effects of remote and classical post-conditioning on ischemia/reperfusion-induced acute kidney injury M. Kadkhodaee, A. Najafi, B. Seifi (Tehran, Iran) O42 – 0012
The early protective effect of Ischemia preconditioning and glutamine pretreatment in renal
ischemia-reperfusion injury of rat
I.Sung Moon, J. Kye Hwang, J. Il Kim (Seoul, Republic of Korea)
New aspects of cell metabolism during IRI Chairs: P1 – 0026
MicroRNA-21 up-regulate HIF-1 alpha expression in hepatocytes during ischemia injury by
targeting PTEN
J. Shan, H. Li, G. Sun, W. Wu, S. Li, D. Long, Y. Li, L. Feng (Chengdu, China)
P2 – 0045
Downregulation of miR-20a decreases HIF-1 alpha and accelerates apoptosis in hypoxia
G. Sun, L. Feng, J. Shan, Y. Guo, T. Yang, S. Li, Y. Li (Chengdu, China)
P3 – 0077 Renal PKC epsilon deficiency attenuates ischemia reperfusion injury via impaired neutrophil infilatration and TNF alpha dependent apoptosis inhibition S. Rong, T. Kirsch, N. Shushakova, J. Menne, M. Leitges, H. Haller, F. Güler (Hannover, Germany) P4 – 0043 Effects of hepatic reperfusion injury on the gene expression of some cytochrome P450 isoforms in rat liver H. Ali Arab, J. Jamshidian, G. Nikbakht, F. Sasani, A. Afkhami (Tehran, Iran) P5 – 0025 OAT1/3 and renal ischemia and reperfusion: Evidence for a role of proximal tubular transporter expression on renal outcome. R. Schneider, M. Meusel, C. Held, C. Wanner, M. Gekle, C. Sauvant (Halle, Germany) P6 – 0009 Cannabidiol treatment ameliorates ischemia/reperfusion renal injury in rats A. Fouad, A. Al-Mulhim, I. Jresat (Saudi, Arabia) P7 – 0010 Effect of methylene blue on the hemodynamic instability resulting from liver ischemia and reperfusion in rabbits R . Rosique, M. Rosique, I. Rosique, L. Tirapelli, P. Évora (Sao Paulo, Brazil) P8 – 0057 Best temperature for static liver graft storage is 1°C an experimental study C. Charrueau, N. Neveux, J-C. Chaumeil, L. Hannoun, L. Cynober, E. Savier (Paris, France) P9 – 0001 Atp and other adenine nucleotide precursors measured in kidneys from DCD by 31p NMR spectroscopy, during hypothermic-oxygenated-pulsatile perfusion, to evaluate their viability J-B. Buchs, F. Lazeyras, L. Buehler, S. Moll, R. Ruttimann, A. Nastasi, P. Morel (Geneva, Switzerland) P10 – 0016
Increased inflammation caused by hyperoxaluria leads to larger renal disfunction in an
experimental model of ischemia and reperfusion
R. Silva, M. Costa, M. Hiyane, M. Cenedeze, H. Pinheiro, N. Camara, A. Pacheco-Silva (Sao Paulo,
Brazil)
P11 – 0034 Anti-rat anti-thymocyte globulin attenuates renal ischaemia-reperfusion injury in rats P. Nesargikar, G. Chavez, B. Spiller, R. Chavez (Cardiff, UK) P12 – 0053 Comparison of Long Term effect of Thymoglobulin Treatment in Patients with High Risk of Delayed Graft Function L. Requião-Moura, E. Ferraz, A. Cristina Matos, E. Tonato, M. Durão, N. Camara, A. Pacheco-Silva (Sao Paulo, Brazil) P13 – 0075 Comparative study between Scot-15® and Perfadex® as lung preservation solutions A. Olland, C. Meers, M. Benahmed, K. Elbayed, S. Wauters, E. Verbeken, G. Verleden, I. Namer, D. Van Raemdonck (Leuven, Belgium) P14 – 0068 Naked Caspase-3 siRNA Is Effective in Cold Preservation, but not in Auto-transplantation of Porcine Kidneys C. Yang, Y. Jia, T. Zhao, Y. Xue, Z. Zhao, J. Zhang, J. Wang, X. Wang, Y. Qiu, M. Lin, D. Zhu, G. Qi, Y. Qiu, Q. Tang, R. Rong, M. Xu, S. Ni, M. Nicholson, T. Zhu, B. Yang (Leicester, UK) P15 – 0055 Organ preservation revisited: anticoagulation rescues borderline kidney grafts S. Tillet, S. Giraud, R. Thuillier, W. Hebrard, M. Petitou, T. Hauet (Poitiers, France) P16 – 0039 Effect of Cardiotrophin-1 on the tissue injury associate to cold ischemia and preservation of the heart and lung. L. Yaremi Quirós, R. Núñez Lozano, P. D Sánchez González, M.B. García Cenador, M.P. Pérez de Obanos, J. Ruiz, F.J. García Criado, J.M. López Novoa (Salamanca, Spain) P17 – 0042 Preliminary study of amniotic fluid stems cell therapy in kidney transplantation E. Baulier, F. Favreau, D. Bon, S. Giraud, S. Joffrion, A. Le Corf, M-L. Bonnet, W. Hebrard, A. Turhan, T. Hauet (Poitiers, France) P18 – 0048 A pilot, randomised, double blind, placebo-controlled, parallel groups, clinical trial to investigate the efficacy and safety of cardiotrophin-1 (CT-1) in kidney transplantation J. Ruiz, M.M. Municio, O. Isidoro (Madrid, Spain) P19 – 0073 Analysis of preservation solution (KPS and UW) with High Resolution Nuclear Magnetic Resonance Spectroscopy during cold preservation: comparison of metabolitc content during cold ischemia with machine perfusion and static storage. D. Bon, P-O. Delpech, T. Khalifeh, N. Boildieu, W. Hébrard, F. Seguin, T. Hauet (Poitiers, France) P20 – 0052
Hypothermic machine perfusion of human liver grafts: Comparison
of single VS dual vessels perfusion.
A. Jomaa, K. Gurusamy, P. Siriwardana, A. Winstanley, I. Claworth, H. Parkes, P. De Muylder, B. Fuller,
B. Davidson (London, UK)
P21 – 0018 MnTMPyP, a selective superoxide dismutase mimetic, reduces oxidative stress in brain dead donors D. Hoeksma, L. Van Dullemen, P. Ottens, S. Veldhuis, R. Ploeg, H. Leuvenink (Groningen, The Netherlands) P22 – 0049 Role of biochemical- and histological-based scores for the prediction of graft failure after liver transplantation G.B. Levi Sandri, Q. Lai, F. Melandro, N. Gugliemo, A. Molinaro, S. Ginanni Corradini, M. Rossi (Roma, Italy) P23 – 0022 Early Urinary Biomarkers of warm and cold ischaemic injury in an experimental kidney model S. A Hosgood, J. P Hunter, M. L Nicholson (Leicester, UK) P24 – 0058 Evaluation of cardiac grafts from non-heart-beating donors : Early reperfusion hemodynamic parameters predict contractile recovery in isolated rat hearts M. Dornbierer, M. Stadelmann, J. Sourdon, B. Gahl, S. Cook, T. Carrel, H. Tevaearai, S. Longnus (Berne, Switzerland) P25 – 0038
Dual kidney transplantation from uncontrolled deceased donors after cardiac arrest (uDDCA)
R. Codas, W. Hanf, B. Mac Gregor, V. Meas Yedid, A. Hadj Aissa, J. Berthiller, G. Perrat, F. Buron, F.
Mraiagh, C. Chauvet, P. Petruzzo, E. Morelon, L. Badet (Lyon, France)
P26 – 0065 Prolonged cold ischaemia potentiates the mitochondrial damage that occurs during warm ischaemia in rat kidneys A. Dare, T. Prime, K. Saeb-Parsy, M. Murphy (Cambridge, UK) P27 – 0005 Hemodynamic study of the portal venous system in a model of warm liver ischemia/reperfusion injury in rats M.F. de Souza Buto, E.R. Ramos Figueira, J. Avancini Rocha Filho, M. Nakatani, E. Ryoiti Tatebe, V. Oliveira Andre, A. Rodrigues de Carvalho Martins, R. Jureidini, M.J. Carvalho Carmona, T. Bacchella, E. Chaib, I. Cecconello, L.A. Carneiro D’Albuquerque (Sao Paulo, Brazil) P28 – 0004
Metabolic changes in a model of warm liver ischemia/reperfusion injury in rats
E. Ryoiti Tatebe, E.R. Ramos Figueira, J. Avancini Rocha Filho, V. Oliveira Andre, M. Nakatani, M.F. de
Souza Buto, R. Jureidini, W. Andraus, T. Bacchella, E. Chaib, I. Cecconello, L.A. Carneiro
D’Albuquerque (Sao Paulo, Brazil)
P29 – 0067 Biomarkers assessing warm ischaemic injury using an isolated porcine kidney haemoreperfusion model B. Yang, S. Hosgood, Z. Da, S. Harper, H. Waller, M. Kay, P. Furness, M. Nicholson (Leicester, UK) P30 – 0051
BacMam ; a novel gene delivery vector for ischaemia
E. Locanto, R. B. Hitchman, L. A. King (Oxford, UK)
P31 – 0062
Ex-vivo normothermic oxygenated perfusion of the liver : a study to identify the ideal perfusate in
a donor after cardiac death (DCD) porcine model.
A. Nassar, G. D’Amico, P. Grady, M. Otto, K. Dympna, X. Zhu, J. Fung, C. Miller, C. Quintini (Cleveland,
USA)
P32 – 0006 Effects of anaesthetic preconditioning with sevoflurane in warm liver ischemia/reperfusion injury in rats E.R. Ramos Figueira, J. Avancini Rocha Filho, B. Beck Schimmer, M. Nakatani, E. Ryoiti Tatebe, V. Oliveira Andre, F.J. Gonçalves Prado, M.J. Carvalho Carmona, P-A. Clavien, L. Augusto Carneiro D’Albuquerque (Sao Paulo, Brazil) P33 – 0028 Ozone postconditioning in renal ischaemia-reperfusion model. Functional and morphological evidences A. Fernández Iglesias, L. González Núñez, S. Rodriguez Salgueiro, J.L. Calunga Fernández, E. Santos Febles (La Habana, Cuba) P34 – 0063
Intermittent Selective Clamping enhances liver tolerance to Ischemia/Reperfusion: a powerful
protective modality in the field of living-related liver transplantation
I. Benmosbah, A. Corlu, H. Duval, S. Grandadam, C. Ribault, K. Boudjema, F. Morel, P. Compagnon
(Rennes, France)

Source: http://irtomit.labo.univ-poitiers.fr/sites/irtomit.labo.univ-poitiers.fr/IMG/pdf/IMIRT_Programme2012.pdf