No está claro cuán grande es el papel de los antibióticos https://antibioticos-wiki.es en las relaciones competitivas entre los microorganismos en condiciones naturales. Zelman Waxman creía que este papel era mínimo, los antibióticos no se forman sino en culturas limpias en entornos ricos. Posteriormente, sin embargo, se descubrió que en muchos productos, la actividad de síntesis de antibióticos aumenta en presencia de otros tipos o productos específicos de su metabolismo.
Redatktionelle tätigkeit & publikationen pd dr. med. d. frey
Redaktionelle Tätigkeit und Gutachter für Zeitschriften
Redaktor
Swiss Knife (offiziel e Zeitschrift der Schweizerischen Gesel schaft für Chirurgie SGC)
Blood Journal of Immunology Journal of Immunotherapy European Journal of Cancer International Journal of Cancer World Journal of Surgery Surgery
Publikationen
Originalarbeiten (peer-reviewed, first or senior author) Frey DM, Droeser RA, Viehl CT, Zlobec I, Lugli A, Zingg U, Oertli D, Kettelhack C, Terrac-
ciano L, Tornillo L. High frequency of tumor-infiltrating FOXP3+ regulatory T cel s predicts im-proved survival in mismatch repair-proficient colorectal cancer patients. Int J Cancer 2010;126:2635-2643
IF 4.734, Ranking 30/141 "Oncology"
Nebiker CA & Frey DM (co-first author), Hamel CT, Oertli D, Kettelhack C. Early versus de-
layed cholecystectomy in patients with biliary acute pancreatitis. Surgery 2009; 145:260-264
IF 3.389 , Ranking 16/148 "Surgery"
Schultz-Thater E & Frey DM (co-first author), Margel i D, Feder-Mengus C, Spagnoli GC, Za-
jac P. Whole blood assessment of antigen specific cellular immune response by real time quantitative PCR: a versatile monitoring and discovery tool. J Transl Med 2008; 6:58.
IF 2.917, Ranking 26/82 "Medicine, research & experimental"
Viehl CT & Frey DM (co-first author), Phommaly C, Chen T, Fleming TP, Gil anders WE,
Eberlein TJ, Goedegebuure PS. Generation of mammaglobin-A-specific CD4 T cel s and iden-tification of candidate CD4 epitopes for breast cancer vaccine strategies. Breast Cancer Res Treat 2007; 109:305-314IF 4.453, Ranking 34/132 "Oncology" Frey DM, Wildisen A, Hamel CT, Zuber M, Oertli D, Metzger J.
Randomized clinical trial of Lichtenstein procedure versus mesh plug for inguinal hernia repair.
IF 4.304, Ranking 3/139 "Surgery" Originalarbeiten (peer-reviewed, co-author)
Grisouard J, Timper K, Bouillet E, Radimerski T, Dembinski K, Frey DM, Peterli R, Zulewski
H, Kel er U, Mül er B, Christ-Crain M. Metformin counters both lipolytic/inflammatory agents-decreased hormone sensitive lipase phosphorylation at Ser-554 and –induced lipolysis in hu-man adipocytes. Arch Physiol Biochem 2011; [Epub ahead of print]
Timper K, Grisouard J, Radimerski T, Dembinski K, Peterli R, Häring A, Frey DM, Zulewski H,
Keller U, Müller B, Christ-Crain M. Glucose-Dependent Insulinotropic Polypeptide (GIP) In-duces Calcitonin Gene-Related Peptide (CGRP)-I and Procalcitonin (Pro-CT) Production in Human Adipocytes. J Clin Endocr Metab 2011; 96:E297-303
IF 6.202, Ranking 10/105 "Endocrinology & Metabolism"
Grisouard J, Bouillet E, Timper K, Radimerski T, Dembinski K, Frey DM, Peterli R, Zulewski
H, Kel er U, Müel er B, Christ-Crain M. Both inflammatory and classical lipolytic pathways are involved in lipopolysaccharides-induced lipolysis in human adipocytes. Innate Immun 2010; [Epub ahead of print]IF 2.206, Ranking 87/128 "Immunology"
Grisouard J, Timper K, Radimerski TM, Frey DM, Peterli R, Kola B, Korbonits M, Herrmann P,
Krähenbühl S, Zulewski H, Keller U, Müller B, Christ-Crain M.
Mechanisms of metformin action on glucose transport and metabolism in human adipocytes. Biochem Pharmacol 2010; 80:1736-1745
Zingg U, Montani M, Frey DM, Dirnhofer S, Esterman AJ, Went P, Oertli D. Tumour-infiltrating
lymphocytes and survival in patients with adenocarcinoma of the oesophagus. Eur J Surg On-col 2010; 36:670-677
IF 2.491, Ranking 32/148 "Surgery"; 74/141 "Oncology"
Zingg U, Forberger J, Frey DM, Estermann AJ, Oertli D, Beck-Schirmer B, Zol inger A.
Inflammatory response in ventilated left and sollapsed right lungs, serum and pleural fluid transthoracic esophagectomy for cancer: time course and differences between the right and left lungs. Eur Cytokine Netw 2010;21:50-57 IF 2.984, Ranking 51/121 "Immunology"
Adamina M, Rosenthal R, Weber WP, Frey DM, Viehl CT, Bolli M, Huegli RW, Jacob AL,
Heberer M, Oertli D, Marti W, Spagnoli GC, Zajac P. Intranodal immunization with a vaccinia virus encoding multiple antigenic epitopes and co-stimulatory molecules in metastatic mela-noma. Molecular Therapy 2009; 18:651-659
IF 5.97, Ranking 6/83 "Medicine, research & experimental"
Fischer M, Timper K, Radimerski T, Dembinski K , Frey DM, Zulewski H, Keller U, Mül er D,
Christ-Crain M and Grisouard J. Metformin induces glucose uptake in human preadipocyte-derived adipocytes from various fat depots. Diabetes, Obesity and Metabolism 2010; 12:356-359
Zingg U, Montani M, Frey DM, Dirnhofer S, Went P, Oertli D.
Influence of neoadjuvant radio-chemotherapy on tumor-infiltrating lymphocytes in squamous esophageal cancer. Eur J Surg Oncol 2009; 35:1268-1272 IF 2.491, Ranking 32/148 "Surgery"; 74/141 "Oncology"
Droeser RA, Frey DM, Oertli D, Kopelman D, Baas-Vrankcken Peeters MJ, Giuliano AE, Dal-
berg K, Kallam R, Nordmann A. Volume-control ed versus no/short-term drainage after axil ary lymph node dissection in breast cancer surgery: A Meta-Analysis. Breast 2009; 19:109-114
IF 2.155, Ranking 10/60 "Obstetrics and Gynaecology"; 96/141 "Oncology"
Rosenthal R, Groeper C, Bracci L, Adamina M, Feder-Mengus C, Zajac P, Bolli M, Weber WP,
Frey DM, Oertli D, Heberer M, Spagnoli GC. Differential responsiveness to IL-2,-7 and -15 common receptor γ chain cytokines by antigen specific peripheral blood naïve or memory CD8+ T cel s from healthy donors and melanoma patients. J Immunother 2009; 32:252-261 IF 3.662, Ranking 31/121 “Immunology”; 15/82 “Medicine, research & experimental”
Adamina M, Weber WP, Rosenthal R, Schumacher R, Zajac P, Gul er U, Frey DM, Oertli D,
Heberer M, Spagnoli GC. Heterologous prime-boost immunotherapy of melanoma patients with Influenza virosomes, and recombinant Vaccinia virus encoding 5 melanoma epitopes and 3 co-stimulatory molecules. A multi-centre phase I/II open labeled clinical trial. Contemp Clin Trials 2007; 29:165-181
IF 1.333, Ranking 49/76 “Medicine, research & experimental”; 140/199 “Pharmcology & Phar-macy”
Timpert K, Frey D, Potthast S. Preoperative diagnosis of concealed duodenal diverticulum. IF 1.976, Ranking 36/85 “Radiology, Nuclear Medicine & Medical Imaging”
Viehl CT, Liyanage UK, Moore TT, Frey DM, Ehlers JP, Eberlein TJ, Goedegebuure PS, Li-
nehan DC. Depletion of CD4+CD25+ regulatory T cells promotes a tumor-specific immune re-sponse in pancreas cancer bearing mice. Ann Surg Oncol 2006; 13:1252-8
IF 3.329, Ranking 47/127 “Oncology”, 11/138 “Surgery”
Liyanage UK, Goedegebuure PS, Moore TT, Viehl CT, Moo-Young TA, Larson JW, Frey DM,
Ehlers JP, Eberlein TJ, Linehan DC. Increased prevalence of regulatory T cel s (Treg) is in-duced by pancreas adenocarcinoma. J Immunother 2006; 29:416-424
IF 4.508, Ranking 26/57 “Immunology”
Weber WP, Feder-Mengus C, Chiarugi A, Rosenthal R, Reschner A, Schumacher R, Zajac P,
Misteli H, Frey DM, Oertli D, Heberer M, Spagnoli GC. Differential effects of the tryptophan metabolite 3-hydroxyanthranilic acid on the proliferation of human CD8+ T cel s induced by TCR triggering or homeostatic cytokines. Eur J Immunol 2006; 36:296-304 IF 4.772, Ranking 14/57 “Immunology”
Viehl CT, Tanaka Y, Chen T, Frey DM, Tran A, Fleming TP, Eberlein TJ, Goedegebuure PS.
Tat mammaglobin fusion protein transduced dendritic cel s stimulate mammaglobin-specific CD4 and CD8 T cel s. Breast Cancer Res Treat 2005; 91:271-278
IF 4.643, Ranking 23/123 “Oncology” Frey DM. Der Patient nach bariatrischem Eingriff. Therapeutische Umschau 2012; Frey DM, Viehl CT. Bariatrische Chirurgie – Eine gewichtige Option in der Diabetes-Therapie. Cardiovasc (not indexed) 2008; 7:11-16
Frey DM. Techniken zur Behandlung von Inguinalhernien. SwissKnife (official Swiss Surgical Frey DM. Die Vielfältigkeit der vliesgebundene Gewebeklebung. SwissKnife (official Swiss
Surgical Journal; not indexed) 2005; 3:18-19
Frey DM, Exner GU, Schreiber A. Angeborene und erworbene Luxationen des Radiusköpf-
chens im Kindesalter. Reposition durch Ulna-Verlängerung/Abwinkelung über Cal otasis. Dis-sertation, Medizinische Fakultät, Universität Zürich 1995
Frey DM. Chirurgische Therapie der morbiden Adipositas: Nutzen, Risiken und Trends, in
Viehl CT und Oertli D (Hrsg.): Facharztprüfung Chirurgie. EMH Schweizerischer Ärzteverlag, Basel 2009; 121-125
PE7734038-1 Naproxen Sodium Tablets 275-550mg Cut Size : 270 x 420 mm 6 pt helv condensed Pharma code: 640 Date: 11.03.2008 (Front) Naproxen Naproxen Sodium Tablets USP • For the relief of the signs and symptoms of rheumatoid arthritis Medication Guide • For the relief of the signs and symptoms of osteoarthritis • For the relief of the signs and symptoms of ankylosing spondyli
De Reparación Integral del Poder Ejecutivo. En nombre de Crysol, la Asociación de ex-presas y de ex-presos políticos de Uruguay expresamos nuestros puntos de vista respecto al proyecto del Poder Ejecutivo, a estudio de esta comisión y por el cual se reconocen las prácticas ilegítimas del estado y el quebrantamiento del estado de derecho desde el 13 de junio de 1968 hasta el fin de la dictad