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Safety Data Sheet according to Regulation (EC) No 1907/2006 1. Identification of the substance/mixture and of the company/undertaking
Doxycycline®, solid (Bulk), <=1%
: Active ingredient: Doxicycline hyclate Doxycyclin® lyophylisate

: Mixture for production of finished medicinal products. : Boehringer Ing. Pharma GmbH & Co.KG Binger Str. 173 55216 Ingelheim am Rhein : Quality & Environmental Health & Safety 2. Hazards Identification

Classification according to Regulation (EC) No. 1272/2008:
This product is a non-hazardous mixture of single components and need not be labelled
according to EC-Directive 1999/45/EC, as amended.
3. Composition/Information on Ingredients
Hazardous ingredients
Chemical name
1,4,4a,5,5a,6,11,12-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphtacenecarboxamide HCl Hemiethanol Hemihydrate Molecular formula: Safety Data Sheet according to Regulation (EC) No 1907/2006 4. First-aid Measures
: Remove from exposure, lie down. Immediately remove contaminated clothing. If danger of loss of consciousness, place patient in recovery position and transport accordingly. Apply artificial respiration if necessary. First aid personnel should pay attention to their own safety. : Immediately wash affected eyes for at least 15 minutes under running water with eyelids held open, consult an eye specialist. : Wash off thoroughly with ample water. Seek medical attention. : Keep patient calm, remove to fresh air, seek medical attention. : Rinse mouth immediately and then drink plenty of water, seek Notes to physician
: Observe the summary of product characteristics of proprietary 5. Fire-fighting Measures
: Use extinguishing measures to suit surroundings., Water, Dry : In case of fire and/or explosion do not breathe fumes. Can be released in case of fire:, Carbon oxides, nitrogen oxides, hydrogen chloride : Collect separately contaminated extinguishing water, do not allow to reach sewage or effluent systems. Dispose of fire debris and contaminated extinguishing water in accordance with official regulations. 6. Accidental Release Measures
: Wear protective equipment. Keep unprotected persons away. : Do not discharge into drains/surface waters/groundwater. : For large amounts: Dampen, pick up mechanically and dispose of. Avoid raising dust. For residues: Use approved industrial vacuum cleaner for removal. Pack in tightly closed containers for disposal. : Never return spills in original containers for re-use. 7. Handling and Storage
: Do not open until use. Provide good ventilation of working area (local exhaust ventilation if necessary). Keep away from sources of ignition - No smoking. Protect from moisture. Safety Data Sheet according to Regulation (EC) No 1907/2006 : General safety and hygiene measures. Hands and/or face should be washed before breaks and at the end of the shift. Store work clothing separately. : Store in original container. Protect from heat and direct sunlight. Jointless smooth floor Keep container tightly closed. : Keep away from food, drink and animal feedingstuffs. Advice 8. Exposure controls/personal protections
Exposure controls
Personal protective equipment
: Use breathing apparatus if exposed to vapours/dust/aerosol. half mask (EN 140) particle filter P2 (EN 143) : Chemical resistant protective gloves (EN 374) : Safety glasses with side-shields (frame goggles) (EN 166) : Laboratory: laboratory coat; factory: disposable Overall. : Only use protective equipment in accordance with national/international regulations. Follow the national regulations about wearing personal protective equipment and the warranty given by the manufacturer for the safe function. : Handle in accordance with good industrial hygiene and safety practice. Do not breathe dust. Avoid contact with skin, eyes and clothing. 9. Physical and Chemical Properties
Safety Data Sheet according to Regulation (EC) No 1907/2006
Further information

Minimum ignition energy
10. Stability and Reactivity
11. Toxicological Information
Safety Data Sheet according to Regulation (EC) No 1907/2006 12. Ecological information
Persistence and degradability
13. Disposal Considerations
: Dispose of in accordance with local regulations. : Packs that cannot be cleaned should be disposed of in the same manner as the contents. Uncontaminated packaging can be recycled. 14. Transport Information

Further information
Not classified as dangerous in the meaning of transport regulations. Not classified as hazardous under transport regulations. For the internal transport: Use only released containers. Use only tightly closed containers. The container must be correctly labelled. Protect container against fall down. Safety Data Sheet according to Regulation (EC) No 1907/2006 15. Regulatory information
National legislation/regulations
WGK 3 highly water endangering Annex 4 VwVwS (Germany) dated Mai, 17 th 1999 16. Other particulars
The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text.


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National Institute of Child Health and Human Development 2008 OPRU Network Meeting August 14–15, 2008 Talaris Conference Center 4000 NE 41st Street Seattle, WA 98105-5428 Meeting Goals This meeting will have four areas of focus and discussion: o Glyburide o Metformin o Caproate o Diclectin o Thyroid o Review of status by compound o Planning for manuscripts and data col

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Standardising Benchmark Problems for the Assessment of Computerised Medical Guideline Systems Kirsty Bradbrook1, Graham Winstanley1, Vivek Patkar2, David Glasspool2 and 1 School of Computing, Mathematical and Information Sciences, University of Brighton 2 Advanced Computing Laboratory, Cancer Research UK Abstract. There is currently a high-level of research being undertaken into the

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