La tétracycline, connue sous le nom commercial Sumycin, agit en bloquant la fixation de l’ARNt sur la sous-unité 30S ribosomale, interrompant l’élongation de la chaîne protéique bactérienne. Ce mécanisme confère une activité sur un spectre large, incluant bactéries Gram positives, Gram négatives, rickettsies et spirochètes. Sa biodisponibilité digestive varie selon la prise alimentaire et les interactions avec les ions divalents comme calcium et magnésium. Sa diffusion tissulaire est importante, notamment dans les voies respiratoires et génito-urinaires. L’élimination se fait par voie rénale et biliaire. Les effets indésirables incluent photosensibilisation, troubles digestifs et coloration dentaire en cas d’administration précoce. Les guides thérapeutiques mentionnent sumycin prix, en soulignant la nécessité de restreindre son utilisation afin de limiter les résistances acquises.
Microsoft word - product_catalogue_intermediates.doc
FRP SERVICES & COMPANY Website: http://www.frpservices.com/ info@frpservices.com Intermediates (Z)-2-(2-Aminothiazole-4-yl)-2-Methoxyimino Acetic Acid CAS# 65872-41-5 The side chain of Cefotaxime, Ceftriaxone, Cefepime, Ceftiofur, Cefteram Ethyl (Z)-2-(2-Aminothiazole-4-yl)-2-Methoxyimino Acetate CAS# 64485-88-7 The side chain of Ceftriaxone and Cefotaxime 2-Mercaptobenzothiazolyl (Z)-2-(2-Aminothiazole-4-yl)-2-Methoxyimino Acetate CAS# 80756-85-0 The side chain of Cefotaxime and Ceftriaxone 4) ATHIAA (Z)-2-(2-Aminothiazole-4-yl)-2-Hydroxyimino Acetic Acid CAS# 66338-96-3 The side chain of Cefdinir Ethyl (Z)-2-(2-Aminothiazole-4-yl)-2-Hydroxyimino Acetate CAS# 64485-82-1 The side chain of Cefdinir, Cefixime and Ceftazidime (Z)-2-(2-Aminothiazole-4-yl)-2-(Tert-Butoxycarbonyl)-Isopropoxyimino Acetic Acid CAS# 86299-46-9 The side chain of Cefotaxime, Ceftriaxone, Cefepime, Ceftiofur, Cefteram FRP SERVICES & COMPANY Website: http://www.frpservices.com/ info@frpservices.com 2-Mercaptobenzothiazolyl (Z)-2-(2-Aminothiazole-4-yl)-2-[(Tert-Butoxycarbonyl)- Isopropoxyimino] Acetate CAS# 89604-92-2 The side chain of Ceftazidime and Aztreonam 2-Mercaptobenzothiazolyl (Z)-2-(2-Aminothiazole-4-yl)-2-(Tert-Butoxycarbonyl)- Methoxyinmino Acetate The side chain of Cefixime 4-Chloro-(Z)-2-Methoxycarbonyl-Methoxyimino-3-Oxobutanoic Acid CAS# 84080-70-6 The side chain of Cefixime (Z)-2-(2-Aminothiazole-4-yl)-2-Methoxycarbonyl- Methoxyimino Acetic Acid The side chain of Cefixime 11) TMHTO 6-Hydroxy-3-Mercapto-2-Methyl-5-Oxo-1,2,4-Triazine CAS# 58909-39-0 The side chain of Ceftriaxone D- -Dihydro Phenyl Glycine CAS# 26774-88-9 The side chain of Cephradine and Cefroxadine FRP SERVICES & COMPANY Website: http://www.frpservices.com/ info@frpservices.com 13) DHGM-Na D- -Dihydro Phenyl Glycine Dane Salt ( Me, Na) CAS# 26774-89-0 The side chain of Cfradine and Cefroxadine 2-Methyl-5-Mercapto-1,3,4-Thiadiazole CAS# 29490-19-5 The side chain of Cefazolin and Cefamandole 1,2,3,4-Tetrazolyl-1-Acetic Acid CAS# 21732-17-2 The side chain of Cefazolin and Ceftezole Sin-Methoxyimino Furanyl Acetic Acid Ammonium Salt CAS# 97148-89-5 The side chain of Cefuroxime Axetil 17) 2-Acetyl CAS# 1192-62-7 The side chain of Cefuroxime Axetil 18)Methoxyamine HCl CAS# 593-56-6 The side chain of Cefuroxime Axetil 2-(2-Aminothiazole-4-yl) Acetic Acid CAS# 29676-71-9 The side chain of Cefotiam N-Ethyl-(2,3-Dioxo-N-Piperzinil)Carbonyl Chloride CAS#59703-00-3 The side chain of Piperaciline, Cefoperazone FRP SERVICES & COMPANY Website: http://www.frpservices.com/ info@frpservices.com 21) HO-DEPC {[(4-Ethyl-2,3-Dioxo-1-Piperazinyl)Carbonyl]Amino}-4-Hydroxy-Benzene Acetic Acid CAS#79868-75-0 The side chain of Cefoperazone 5-Mercapto-1-Methyl-1,2,3,4-Tetrazole CAS#13183-79-4 The side chain of Cefoperazone, Cefteram, Cefamandole and Cefotetan 2-(2-Mercapto-4-Methyl-1,3-Thiazole-5-yl) Acetic Acid CAS# 34272-64-5 The side chain of Cefodizim 1-Sulfonylmethyl-5-Mercaptotetrazole Disodium Salt CAS# 66242-82-8 The side chain of Cefonicid 25) 5-Methyl-1H-Tetrazole CAS# 4076-36-2 26) 1-Hydroxyethyl-5-Mercapto-1H-Tetrazolyl CAS# 56610-81-2 27) D-(-)-Phenylglycine CAS# 875-74-1 The side chain of Cefaclor and Ampicillin 28) L-(+)-Phenylglycine CAS# 2935-35-5 The side chain of Cefodizim 29) D-(-)-Phenylglycine Dane Salt (Et, K) CAS# 961-69-3 The side chain of Ampicillin, Cephalexin and Cefaclor 30) D-(-)-α-P-Hydroxy Phenylglycine CAS# 22818-40-2 FRP SERVICES & COMPANY Website: http://www.frpservices.com/ info@frpservices.com 31) D-(-)-α-P-Hydroxy Phenylglycine Dane Salt CAS# 69416-61-1 The side chain of Amoxycillin and Cefadroxil 32) 3-Thiophene CAS# 21080-92-2 The intermediate of Ticarcillin 33)Ticcarcillin acid CAS# 34787-01-4 The intermediate of Ticarcillin 34) 1H-1,2,3-Triazole CAS# 288-36-8 The intermediate of Tazobactam 35) CBZTA N-Benzyloxycarbonyl-L-Threoninamide CAS# 49705-98-8 36) 1-Acetidinesulfonic 3-Amino-2-Methyl- 4-oxo-(2s-trans) The intermediate of Aztreonam 37) 7-AVCA CAS# 79349-2-9 7-Amino-3-Vinyl-3-Cephem-4-Carboxylic Acid The intermediate of Cefdinir, Cefixime 7-Phenylacetamido-3-Hydroxy-3-Cephem-4-Carboxylic acid Diphenyl methyl ester The intermediate of Cefaclor 7-Amino-3-Propenylcephem-4-Carboxylic acid The intermediate of Cefprozil 2,4-Dichloro-5-Fluoro-Acetophenone CAS# 704-10-9 The intermediate of Ciprofloxacin and Enrofloxacin FRP SERVICES & COMPANY Website: http://www.frpservices.com/ info@frpservices.com 1,3-Dichloro-4-Fluoro-Benzene CAS# 1435-48-9 42) Q-ACID 7-Chloro-1-Cyclopropyl-6-Fluoro-4-Oxo-3-Quinoline Carboxylic Acid The intermediate of Ciprofloxacin 43) Ofloxacin Carboxylic Acid The intermediate of Ofloxacin 44) 1-Acetone-Oxo-3,4-DifluoroNitrobenzene The intermediate of Ofloxacin 45) Levofloxacin Carboxylic Acid The intermediate of Levofloxacin 46) 7-Chloro-1-Cycllopropyl-6-Fluoro-1,4-Dihydro-4-Oxo-1,8-Naphthyridine-3- Carboxylic Acid The intermediate of the New-Quinolone antibiotics FRP SERVICES & COMPANY Website: http://www.frpservices.com/ info@frpservices.com 7-Chloro-1-(2,4-Difluorophenyl)-6-Fluoro-1,4-Dihydro-4-Oxo-1,8-Naphthyridine- 3-Carboxylic Acid Ethyl Ester The Intermediate of Trovafloxacin Mesylate,Alatrofloxacin,Tosufloxacin. 48) p-Fluoro Nitrobenzene 49)3-Chloro-4-fluoro Aniline CAS# 367-21-5 50) 2,4,5-Trifluoro-3-Methoxy-benzoic CAS# 112811-65-1 51) 2-Methyl Piperazine CAS# 109-07-9 52) Tyramine CAS# 51-76-2 The intermediate of Benzafibrate 2-Phenylpropane-1,3-diol CAS# 570-95-2 The intermediate of Felbamate 54) Cefetamet CAS# 65052-63-3 55) Cefuroxime CAS# 55268-75-2 56) Ceftazidime CAS# 72558-82-8 57) Cefixime CAS# 79350-37-1 58) Cefotezoxime 59) Cefotezoxime 60) CBZ-L-Valine CAS# 1149-26-4 --Intermediate for Valaciclovir and Valsartan 61) CBZ-S-Phenyl-L-Cysteine CAS# 159453-24-4 --Intermediate for Nelfinavir 62) (R)-(+)-1,2-Epoxypropane CAS# 15448-47-2 --Intermediate for Tenofovir FRP SERVICES & COMPANY Website: http://www.frpservices.com/ info@frpservices.com 63) (R)-(-)-1,2-Propanediol CAS# 4254-14-2 --Intermediate for Tenofovir 64) (R)-(+)-Propylene carbonate CAS# 16606-55-6 --Intermediate for Tenofovir 65) (S)-(+)-Epichlorohydrin CAS# 67843-74-7 66) (R)-Glycidyl butyrate CAS# 60456-26-0 --Intermediate for Linezolid 67) (S)-Glycidyl tosylate CAS# 26550-55-0 68) (R)-(-)-1-Amino-2-propanol CAS# 2799-16-8 69) Di-p-toluoyl-L-tartaric CAS# 32634-66-5 70) (S)-(+)-1-Amino-2-propanol CAS# 2799-17-9 71) Di-p-toluoyl-D-tartaric CAS# 32634-68-7 72) OBPA; 10,10'-oxybisphenoxarsine CAS# 58-36-6 5-Chloro-8-Hydroxyquinoline CAS# 130-16-5 74) D-mandelic CAS# 611-71-2
Copyright ª 2006 by the Johns Hopkins Bloomberg School of Public HealthAll rights reserved; printed in U.S.A. Advance Access publication November 6, 2006Antiviral Effects on Influenza Viral Transmission and Pathogenicity:Observations from Household-based TrialsM. Elizabeth Halloran1,2, Frederick G. Hayden3, Yang Yang1, Ira M. Longini, Jr.1,2, and ArnoldS. Monto41 Program in Biostatistics
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