Original publications (takehiko kamijo, m.d., ph.d.)

Original Publications (Takehiko Kamijo, M.D., Ph.D.)

1. Ichikawa M, Yanagisawa M, Kawai H, Kamijo T, Komiyama A, Akabane T
Spontaneous improvement of juvenile rheumatoid arthritis after T
lymphocytosis with suppressor phenotype and function.
J Clin Lab Immunol. 1988 Dec;27(4):197-201.
2. Kamijo K, Kamijo T, Ueno I, Osumi T, Hashimoto T
Nucleotide sequence of the human 70 kDa peroxisomal membrane protein: a
member of ATP-binding cassette transporters.
Biochim Biophys Acta. 1992 Feb 11;1129(3):3
3. Kamijo T, Aoyama T, Miyazaki J, Hashimoto T
Molecular cloning of the cDNAs for the subunits of rat mitochondrial fatty
acid beta-oxidation multienzyme complex. Structural and functional
relationships to other mitochondrial and peroxisomal beta-oxidation
enzymes.
J Biol Chem. 1993 Dec 15;268(35):26452-60.
4. Aoyama T, Tsushima K, Souri M, Kamijo T, Suzuki Y, Shimozawa N, Orii
T, Hashimoto T
Molecular cloning and functional expression of a human peroxisomal
acyl-coenzyme A oxidase.
Biochem Biophys Res Commun. 1994 Feb 15;198(3):1113-8.
5. Kamijo T, Aoyama T, Komiyama A, Hashimoto T
Structural analysis of cDNAs for subunits of human mitochondrial fatty acid
beta-oxidation trifunctional protein.
Biochem Biophys Res Commun. 1994 Mar 15;199(2):818-25.
6. Kamijo T, Wanders RJ, Saudubray JM, Aoyama T, Komiyama A,
Hashimoto T
Mitochondrial trifunctional protein deficiency. Catalytic heterogeneity of the
mutant enzyme in two patients.
J Clin Invest. 1994 Apr;93(4):1740-7.
7. Aoyama T, Souri M, Kamijo T, Ushikubo S, Hashimoto T Peroxisomal acyl-coenzyme A oxidase is a rate-limiting enzyme in a very-long-chain fatty acid beta-oxidation system. Biochem Biophys Res Commun. 1994 Jun 30;201(3):1541-7. 8. Aoyama T, Ueno I, Kamijo T, Hashimoto T Rat very-long-chain acyl-CoA dehydrogenase, a novel mitochondrial acyl-CoA dehydrogenase gene product, is a rate-limiting enzyme in long-chain fatty acid beta-oxidation system. cDNA and deduced amino acid sequence and distinct specificities of the cDNA-expressed protein. J Biol Chem. 1994 Jul 22;269(29):19088-94. 9. IJlst L, Wanders RJ, Ushikubo S, Kamijo T, Hashimoto T Molecular basis of long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency: identification of the major disease-causing mutation in the alpha-subunit of the mitochondrial trifunctional protein. Biochim Biophys Acta. 1994 Dec 8;1215(3):347-50. 10. Aoyama T, Souri M, Ushikubo S, Kamijo T, Yamaguchi S, Kelley RI, Rhead WJ, Uetake K, Tanaka K, Hashimoto T Purification of human very-long-chain acyl-coenzyme A dehydrogenase and characterization of its deficiency in seven patients. J Clin Invest. 1995 Jun;95(6):2465-73. 11. Aoyama T, Souri M, Ueno I, Kamijo T, Yamaguchi S, Rhead WJ, Tanaka K, Hashimoto T Cloning of human very-long-chain acyl-coenzyme A dehydrogenase and molecular characterization of its deficiency in two patients. Am J Hum Genet. 1995 Aug;57(2):273-83. 12. Sawai N, Koike K, Ito S, Okumura N, Kamijo T, Shiohara M, Amano Y, Tsuji K, Nakahata T, Oda M Aberrant growth of granulocyte-macrophage progenitors in juvenile chronic myelogenous leukemia in serum-free culture. Exp Hematol. 1996 Feb;24(2):116-22. 13. Ushikubo S, Aoyama T, Kamijo T, Wanders RJ, Rinaldo P, Vockley J, Hashimoto T Molecular characterization of mitochondrial trifunctional protein deficiency: formation of the enzyme complex is important for stabilization of both alpha- and beta-subunits. Am J Hum Genet. 1996 May;58(5):979-88. 14. Kamijo T, Indo Y, Souri M, Aoyama T, Hara T, Yamamoto S, Ushikubo S, Rinaldo P, Matsuda I, Komiyama A, Hashimoto T Medium chain 3-ketoacyl-coenzyme A thiolase deficiency: a new disorder of mitochondrial fatty acid beta-oxidation. Pediatr Res. 1997 Nov;42(5):569-76. 15. Kamijo T, Zindy F, Roussel MF, Quelle DE, Downing JR, Ashmun RA, Grosveld G, Sherr CJ Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF. Cell. 1997 Nov 28;91(5):649-59. 16. Kamijo T, Koike K, Takeuchi K, Higuchi T, Sawai N, Kikuchi T, Tsumura H, Akiyama H, Koike T, Ishii E, Komiyama A Analysis of synergism between stem cell factor and granulocyte-macrophage colony-stimulating factor on human megakaryoblastic cells: an increase in tyrosine phosphorylation of 145 kDa subunit of c-kit in two-factor combination. Leuk Res. 1997 Nov-Dec;21(11-12):1097-106. 17. Ma F, Koike K, Higuchi T, Kinoshita T, Takeuchi K, Mwamtemi HH, Sawai N, Kamijo T, Shiohara M, Horie S, Kawa S, Sasaki Y, Hidaka E, Yamagami O, Yamashita T, Koike T, Ishii E, Komiyama A Establishment of a GM-CSF-dependent megakaryoblastic cell line with the potential to differentiate into an eosinophilic lineage in response to retinoic acids. Br J Haematol. 1998 Feb;100(2):427-35. 18. Kamijo T, Weber JD, Zambetti G, Zindy F, Roussel MF, Sherr CJ Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2. Proc Natl Acad Sci U S A. 1998 Jul 7;95(14):8292-7. 19. Zindy F, Eischen CM, Randle DH, Kamijo T, Cleveland JL, Sherr CJ, Roussel MF Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization. Genes Dev. 1998 Aug 1;12(15):2424-33. 20. Kamijo T, Bodner S, van de Kamp E, Randle DH, Sherr CJ Tumor spectrum in ARF-deficient mice. Cancer Res. 1999 May 1;59(9):2217-22. 21. Sawai N, Koike K, Mwamtemi HH, Kinoshita T, Kurokawa Y, Sakashita K, Higuchi T, Takeuchi K, Shiohara M, Kamijo T, Ito S, Kato T, Miyazaki H, Yamashita T, Komiyama A Thrombopoietin augments stem cell factor-dependent growth of human mast cells from bone marrow multipotential hematopoietic progenitors. Blood. 1999 Jun 1;93(11):3703-12. 22. Kamijo T, van de Kamp E, Chong MJ, Zindy F, Diehl JA, Sherr CJ, McKinnon PJ Loss of the ARF tumor suppressor reverses premature replicative arrest but not radiation hypersensitivity arising from disabled atm function. Cancer Res. 1999 May 15;59(10):2464-9. 23. Kinoshita T, Koike K, Mwamtemi HH, Ito S, Ishida S, Nakazawa Y, Kurokawa Y, Sakashita K, Higuchi T, Takeuchi K, Sawai N, Shiohara M, Kamijo T, Kawa S, Yamashita T, Komiyama A Retinoic acid is a negative regulator for the differentiation of cord blood-derived human mast cell progenitors. Blood 2000 May 1;95(9):2821-8 24. Sawai N, Koike K, Mwamtemi HH, Ito S, Kurokawa Y, Sakashita K, Kinoshita T, Higuchi T, Takeuchi K, Shiohara M, Kamijo T, Higuchi Y, Miyazaki H, Kato T, Kobayashi M, Miyake M, Yasui K, Komiyama A. Thrombopoietin enhances neutrophil production by bone marrow hematopoietic progenitors with the aid of stem cell factor in congenital neutropenia. J Leukoc Biol. 2000 Jul;68(1):137-43. 25. Mwamtemi HH, Koike K, Kinoshita T, Ito S, Ishida S, Nakazawa Y, Kurokawa Y, Shinozaki K, Sakashita K, Takeuchi K, Shiohara M, Kamijo T, Yasui Y, Ishiguro A, Kawano Y, Kitano K, Miyazaki H, Kato T, Sakuma S, Komiyama A. An increase in circulating mast cell colony-forming cells in asthma. J Immunol. 2001 Apr 1;166(7):4672-7. 26. Hagimoto R, Koike K, Sakashita K, Ishida T, Nakazawa Y, Kurokawa Y, Kamijo T, Saito S, Hiraoka A, Kobayashi M, Komiyama A. A possible role for maternal HLA antibodyin a case of alloimmune neonatal neutropenia. Transfusion. 2001 May;41(5):615-20. 27. Kurokawa Y, Ishida F, Kamijo T, Kunishima S, Kenny D, Kitano K, Koike K. A missense mutation (tyr88 to cys) in the platelet membrane glycoprotein Ibbeta gene affects GPIb/IX complex expression--Bernard-Soulier syndrome in the homozygous form and giant platelets in the heterozygous form. Thromb Haemost. 2001 Nov;86(5):1249-56. 28. Sakashita K, Koike K, Kinoshita T, Shiohara M, Kamijo T, Taniguchi S, Kubota T. Dynamic DNA methylation change in the CpG island region of p15 during human myeloid development. J Clin Invest. 2001 Oct;108(8):1195-204. 29. Chisuwa H, Hashikura Y, Nakazawa Y, Kamijo T, Nakazawa K, Nakayama J, Oh-Ishi T, Ikegami T, Terada M, Kawasaki S. Fatal hemophagocytic syndrome after living-related liver transplantation: a report of two cases. Transplantation. 2001 Dec 15;72(11):1843-6. 30. Kamijo T, Koike K, Nakazawa Y, Takeuchi K, Ishii E, Komiyama A. Synergism between stem cell factor and granulocyte-macrophage colony-stimulating factor on cell proliferation by induction of cyclins. Cytokine. 2002 Nov;19(6):267-75. 31. Nakazawa Y, Kamijo T, Koike K, Noda T. ARF tumor suppressor induces mitochondria-dependent apoptosis by modulation of mitochondrial Bcl-2 family proteins. J Biol Chem. 2003 Jul 25;278(30):27888-95. Epub 2003 May 09. 32. Tanaka M, Kamijo T, Koike K, Ueno I, Nakazawa Y, Kurokawa Y, Sakashita K, Komiyama A, Fujisawa K. Specific autoantibodies to platelet glycoproteins in Epstein-Barr virus-associated immune thrombocytopenia. Int J Hematol. 2003 Aug;78(2):168-70. 33. Takeuchi K, Koike K, Kamijo T, Ishida S, Nakazawa Y, Kurokawa Y, Sakashita K, Kinoshita T, Matsuzawa S, Shiohara M, Yamashita T, Nakajima M, Komiyama A. STI571 inhibits growth and adhesion of human mast cells in culture. J Leukoc Biol. 2003 Dec;74(6):1026-34. Epub 2003 Sep 02. 34. Nakazawa Y, Sakashita K, Kinoshita M, Saida K, Shigemura T, Yanagisawa R, Shikama N, Kamijo T, Koike K. Successful unrelated cord blood transplantation using a reduced-intensity conditioning regimen in a 6-month-old infant with congenital neutropenia complicated by severe pneumonia. Int J Hematol. 2004 Oct;80(3):287-90 35. Uchida C, Miwa S, Kitagawa K, Hattori T, Isobe T, Otani S, Oda T, Sugimura H, Kamijo T, Ookawa K, Yasuda H, Kitagawa M. Enhanced Mdm2 activity inhibits pRB function via ubiquitin-dependent degradation. EMBO J. 2005 Jan 12;24(1):160-169. Epub 2004 Dec 02. 36. Iwama A, Oguro H, Negishi M, Kato Y, Morita Y, Tsukui H, Ema H, Kamijo T, Katoh-Fukui Y, Koseki H, van Lohuizen M, Nakauchi H. Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1. Immunity. 2004 Dec;21(6):843-51. 37. Zhao XY, Sakashita K, Kamijo T, Hidaka E, Sugane K, Kubota T, Koike K Granulocyte-macrophage colony-stimulating factor induces de novo methylation of the p15 CpG island in hematopoietic cells Cytokine. 2005 Aug 7;31(3):203-12. 38. Matsuzaki S, Matsuda K, Miki J, Nakazawa Y, Sakashita K, Kamijo T, Hidaka E, Koike K Development of two cytogenetically abnormal clones from multipotential hematopoietic stem cells in a patient with juvenile myelomonocytic leukemia Leuk Res. 2005 Sep;29(9):1069-72. 39. Igarashi S, Manabe A, Ohara A, Kumagai M, Saito T, Okimoto Y, Kamijo T, Isoyama K, Kajiwara M, Sotomatsu M, Sugita K, Sugita K, Maeda M, Yabe H, Kinoshita A, Kaneko T, Hayashi Y, Ikuta K, Hanada R, Tsuchida M. No advantage of dexamethasone over prednisolone for the outcome of standard- and intermediate-risk childhood acute lymphoblastic leukemia in the Tokyo Children's Cancer Study Group L95-14 protocol. J Clin Oncol. 2005 Sep 20;23(27):6489-98. 40 Matsuda K, Matsuzaki S, Miki J, Hidaka E, Yanagisawa R, Nakazawa Y, Sakashita K, Kamijo T, Asami K, Sano K, Koike K. Chromosomal change during 6-mercaptopurine (6-MP) therapy in juvenile myelomonocytic leukemia: the growth of a 6-MP-refractory clone that already exists at onset. Leukemia. 2006 Mar;20(3):485-90. 41. Oguro H, Iwama A, Morita Y, Kamijo T, van Lohuizen M, and Nakauchi H Differential impact of derepressed Ink4a and Arf on hematopoietic stem cells and their bone marrow microenvironment in Bmi 1-deficient mice. J Exp Med. 2006 Oct 2;203(10):2247-53. 42. Takada Y, Isono K, Shinga J, Turner JM, Kitamura H, Ohara O, Watanabe G, Singh PB, Kamijo T, Jenuwein T, Burgoyne PS, Koseki H. Mammalian Polycomb Scmh1 mediates exclusion of Polycomb complexes from the XY body in the pachytene spermatocytes. Development. 2007 Feb;134(3):579-90. 43. Nakamura Y, Ozaki T, Niizuma H, Ohira M, Kamijo T, Nakagawara A. Functional characterization of a new p53 mutant generated by homozygous deletion in a neuroblastoma cell line. Biochem Biophys Res Commun. 2007 Mar 23;354(4):892-8. 44. Nakazawa Y, Saito S, Hasegawa Y, Yanagisawa R, Sakashita K, Kamijo T, Miyazaki T, Sato S, Ikeda H, Ikebuchi K, Koike K. A possible role for the production of multiple HLA antibodies in fatal platelet transfusion refractoriness after peripheral blood progenitor cell transplantation from the mother in a patient with relapsed leukemia. Transfusion. 2007 Feb;47(2):326-34. 45. Takahashi M, Ozaki T, Takahashi A, Miyauchi M, Ono S, Takada N, Koda T, Todo S, Kamijo T, Nakagawara A. DFF45/ICAD restores cisplatin-induced nuclear fragmentation but not DNA cleavage in DFF45-deficient neuroblastoma cells. Oncogene. 2007 Aug 16;26(38):5669-73. Epub 2007 Mar 12. 46. Miki J, Fujimura Y, Koseki H, Kamijo T. Polycomb complexes regulate cellular senescence by repression of ARF in coordination with E2F3 Genes To Cells. 2007 Dec;12(12):1371-82. 47. Kurata K, Yanagisawa R, Ohira M, Kitagawa M, Nakagawara A, Kamijo T. Stress via p53 pathway causes apoptosis by mitochondrial Noxa upregulation in doxorubicin-treated neuroblastoma cells. Oncogene. 2008 Jan 31;27(6):741-54. 48 Okoshi R, Ozaki T, Yamamoto H, Ando K, Koida N, Ono S, Koda T, Kamijo T, Nakagawara A, Kizaki H. Activation of AMP-activated protein kinase (AMPK) induces p53-dependent apototic cell death in response to energetic stress. J Biol Chem. 2008, Feb 15;283(7):3979-87. 49. Koida N, Ozaki T, Yamamoto H, Ono S, Koda T, Ando K, Okoshi R, Kamijo T, Omura K, Nakagawara A. Inhibitory role of Plk1 in the regulation of p73-dependent apoptosis through physical interaction and phosphorylation. J Biol Chem. 2008 Mar 28;283(13):8555-63. Epub 2008 Jan 3. 50. Wang H, Ozaki T, Shamim Hossain M, Nakamura Y, Kamijo T, Xue X, Nakagawara A. A newly identified dependence receptor UNC5H4 is induced during DNA damage-mediated apoptosis and transcriptional target of tumor suppressor p53. Biochem Biophys Res Commun. 2008 Jun 13;370(4):594-8. 51. Abe M, Kamijo T, Matsuzawa S, Miki J, Nakazawa Y, Sakashita K, Okabe T, Honda T, Mitsuyama J, and Koike K High incidence of meropenem resistance among alpha-hemolytic streptococci in children with cancer Pediatric International, 2008, in press 52. Hossain MS, Ozaki T, Wang H, Nakagawa A, Takenobu H, Ohira M, Kamijo T, Nakagawara A. N-MYC promotes cell proliferation through a direct transactivation of neuronal leucine-rich repeat protein-1 (NLRR1) gene in neuroblastoma. Oncogene. 2008 Oct 16;27(46):6075-82. Epub 2008 Jun 30. 53. Ando K, Ohira M, Ozaki T, Nakagawa A, Akazawa K, Suenaga Y, Nakamura Y, Koda T, Kamijo T, Murakami Y, Nakagawara A. Expression of TSLC1, a candidate tumor suppressor gene mapped to chromosome 11q23, is downregulated in unfavorable neuroblastoma without promoter hypermethylation. Int J Cancer. 2008 Nov 1;123(9):2087-94. 54. Yanagisawa R, Nakazawa Y, Sakashita K, Tanaka M, Shikama N, Kamijo T, Shiohara M, Koike K. Low toxicity of a conditioning with 8-Gy total body irradiation, fludarabine and cyclophosphamide as preparative regimen for allogeneic hematopoietic stem cell transplantation in pediatric hematological malignancies. Pediatr Transplant. 2008 Dec 16. [Epub ahead of print]

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