La tétracycline, connue sous le nom commercial Sumycin, agit en bloquant la fixation de l’ARNt sur la sous-unité 30S ribosomale, interrompant l’élongation de la chaîne protéique bactérienne. Ce mécanisme confère une activité sur un spectre large, incluant bactéries Gram positives, Gram négatives, rickettsies et spirochètes. Sa biodisponibilité digestive varie selon la prise alimentaire et les interactions avec les ions divalents comme calcium et magnésium. Sa diffusion tissulaire est importante, notamment dans les voies respiratoires et génito-urinaires. L’élimination se fait par voie rénale et biliaire. Les effets indésirables incluent photosensibilisation, troubles digestifs et coloration dentaire en cas d’administration précoce. Les guides thérapeutiques mentionnent sumycin prix, en soulignant la nécessité de restreindre son utilisation afin de limiter les résistances acquises.

Medication advisory for patients with alzheimer’s disease

MEDICATION ADVISORY FOR PATIENTS WITH DEMENTIA
BRAND NAME
GENERIC NAME
DAILY DOSE RANGE
IMPORTANT SIDE EFFECTS
OLD ANTIPSYCHOTIC MEDICATIONS
1.
NEW ANTIPSYCHOTIC MEDICATIONS
8.
ANTIDEPRESSANTS
13.
ANTIANXIETY MEDICATIONS
29.
MOOD/BEHAVIOR STABILIZERS
35.
IMPORTANT SIDE EFFECTS
1. CNS (Sedation/dizziness) 2. Mental status changes (confusion/agitation) 3. Movement disorders (stiffness,
restlessness, tardive dyskinesia, tremors) 4. Insomnia 5. GI disturbance (nausea/vomiting/diarrhea) 6. Anticholinergic
(dry mouth, blurred vision, urinary retention) 7. Blood pressure effects(lowered/raised) 8. Cardiac Effects (heart
rate/rhythm) 9. Reduced seizure threshold 10. Special monitoring required (blood/liver/kidney) 11. Important drug
interactions 12. Psychological or physical dependence 13. Dermatological effects 14. Increased risk of falls
S=SAFE: Safe when used for specific indications in recommended doses and not interacting with other medicines.
C=CAUTION: Can be used but requires careful monitoring.
A=AVOID: Should be used by practitioner with expertise in geriatric psychopharmacology.
R=RESTRICTIVE: Has potential for serious side effects. Experts in dementia and geriatric psychopharmacology should use these
NSR =SURVEYOR REVIEW: Medication produces automatic surveyor review.
MEDICATION ADVISORY FOR PATIENTS WITH DEMENTIA
BRAND NAME
GENERIC NAME
DAILY DOSE RANGE
IMPORTANT SIDE EFFECTS
MEMORY ENHANCERS
40.
OTHER MEDICATIONS FOR ALZHEIMER’S DISEASE
46.
SEDATIVE / SLEEP MEDICATIONS
48.
NARCOTIC PAIN RELIEVERS
58.
NON-NARCOTIC PAIN RELIEVERS
64.
APPETITE ENHANCERS
69.
IMPORTANT SIDE EFFECTS
1. CNS (Sedation/dizziness) 2. Mental status changes (confusion/agitation) 3. Movement disorders (stiffness,
restlessness, tardive dyskinesia, tremors) 4. Insomnia 5. GI disturbance (nausea/vomiting/diarrhea) 6. Anticholinergic
(dry mouth, blurred vision, urinary retention) 7. Blood pressure effects(lowered/raised) 8. Cardiac Effects (heart
rate/rhythm) 9. Reduced seizure threshold 10. Special monitoring required (blood/liver/kidney) 11. Important drug
interactions 12. Psychological or physical dependence 13. Dermatological effects 14. Increased risk of falls
S=SAFE: Safe when used for specific indications in recommended doses and not interacting with other medicines.
C=CAUTION: Can be used but requires careful monitoring.
A=AVOID: Should be used by practitioner with expertise in geriatric psychopharmacology.
R=RESTRICTIVE: Has potential for serious side effects. Experts in dementia and geriatric psychopharmacology should
NSR=SURVEYOR REVIEW: Medication produces automatic surveyor review.

Source: http://www.alzbrain.org/pdf/handouts/2043.%20MEDICATION%20ADVISORY%20FOR%20PATIENTS%20WITH%20ALZHEIMER'S%20DISEASE-final%20final%20one.pdf